7TZV
 
 | | Structure of DriD C-domain bound to 9mer ssDNA | | Descriptor: | DNA (5'-D(*TP*AP*GP*TP*CP*TP*AP*CP*T)-3'), WYL domain-containing protein | | Authors: | Schumacher, M.A, Laub, M. | | Deposit date: | 2022-02-16 | | Release date: | 2022-06-01 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD.
Genes Dev., 36, 2022
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4GCL
 | | structure of no-dna factor | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*AP*GP*TP*GP*AP*GP*TP*AP*CP*TP*CP*AP*CP*T)-3'), Nucleoid occlusion factor SlmA | | Authors: | Schumacher, M.A. | | Deposit date: | 2012-07-30 | | Release date: | 2013-06-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4GCT
 | | structure of No factor protein-DNA complex | | Descriptor: | DNA (5'-D(*TP*TP*AP*CP*GP*TP*GP*AP*GP*TP*AP*CP*TP*CP*AP*CP*GP*TP*AP*A)-3'), Nucleoid occlusion factor SlmA | | Authors: | Schumacher, M.A. | | Deposit date: | 2012-07-30 | | Release date: | 2013-06-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4GCK
 | | structure of no-dna complex | | Descriptor: | DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*TP*CP*AP*C)-3'), Nucleoid occlusion factor SlmA | | Authors: | Schumacher, M.A. | | Deposit date: | 2012-07-30 | | Release date: | 2013-06-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4GFL
 | | NO mechanism, slma | | Descriptor: | Nucleoid occlusion factor SlmA | | Authors: | Schumacher, M.A. | | Deposit date: | 2012-08-03 | | Release date: | 2013-06-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4FE4
 | | Crystal structure of apo E. coli XylR | | Descriptor: | Xylose operon regulatory protein | | Authors: | Schumacher, M.A, Ni, L. | | Deposit date: | 2012-05-29 | | Release date: | 2012-12-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | Structures of the Escherichia coli transcription activator and regulator of diauxie, XylR: an AraC DNA-binding family member with a LacI/GalR ligand-binding domain.
Nucleic Acids Res., 41, 2013
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4GFK
 | | structures of NO factors | | Descriptor: | Nucleoid occlusion factor SlmA | | Authors: | Schumacher, M.A. | | Deposit date: | 2012-08-03 | | Release date: | 2013-06-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3JS6
 | | Crystal structure of apo psk41 parM protein | | Descriptor: | Uncharacterized ParM protein | | Authors: | Schumacher, M.A, Xu, W, Firth, N. | | Deposit date: | 2009-09-09 | | Release date: | 2010-01-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure and filament dynamics of the pSK41 actin-like ParM protein: implications for plasmid DNA segregation.
J.Biol.Chem., 285, 2010
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3M8F
 | | Protein structure of type III plasmid segregation TubR mutant | | Descriptor: | Putative DNA-binding protein | | Authors: | Schumacher, M.A, Ni, L. | | Deposit date: | 2010-03-17 | | Release date: | 2010-07-07 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3M8K
 | | Protein structure of type III plasmid segregation TubZ | | Descriptor: | FtsZ/tubulin-related protein | | Authors: | Schumacher, M.A, Ni, L. | | Deposit date: | 2010-03-18 | | Release date: | 2010-07-07 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3M9A
 | | Protein structure of type III plasmid segregation TubR | | Descriptor: | Putative DNA-binding protein | | Authors: | Schumacher, M.A, Ni, L. | | Deposit date: | 2010-03-21 | | Release date: | 2010-07-07 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition.
Proc.Natl.Acad.Sci.USA, 107, 2010
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7RMW
 | | Crystal structure of B. subtilis PurR bound to ppGpp | | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, Pur operon repressor | | Authors: | Schumacher, M.A. | | Deposit date: | 2021-07-28 | | Release date: | 2021-12-22 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus.
Nucleic Acids Res., 50, 2022
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3EZ7
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3EZ9
 | | Partition Protein | | Descriptor: | MAGNESIUM ION, ParA | | Authors: | Schumacher, M.A. | | Deposit date: | 2008-10-22 | | Release date: | 2009-06-02 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA.
Embo J., 28, 2009
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3EZ2
 | | Partition protein-ADP complex | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | | Authors: | Schumacher, M.A, Dunham, T.D, Xu, W, Funnell, B. | | Deposit date: | 2008-10-22 | | Release date: | 2009-06-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA.
Embo J., 28, 2009
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3EZF
 | | Partition Protein | | Descriptor: | ParA, SULFATE ION | | Authors: | Schumacher, M.A. | | Deposit date: | 2008-10-22 | | Release date: | 2009-06-02 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA.
Embo J., 28, 2009
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3EZ6
 | | Structure of parA-ADP complex:tetragonal form | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Plasmid partition protein A | | Authors: | Schumacher, M.A. | | Deposit date: | 2008-10-22 | | Release date: | 2009-06-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA.
Embo J., 28, 2009
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4OAZ
 | | BldD CTD-c-di-GMP complex | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Putative DNA-binding protein | | Authors: | Schumacher, M.A, Tschowri, N, Buttner, M, Brennan, R.G. | | Deposit date: | 2014-01-06 | | Release date: | 2014-11-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
Cell(Cambridge,Mass.), 158, 2014
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5HT1
 | | Structure of apo C. glabrata FKBP12 | | Descriptor: | FK506-binding protein 1 | | Authors: | Schumacher, M.A. | | Deposit date: | 2016-01-26 | | Release date: | 2016-09-14 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.651 Å) | | Cite: | Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.
Mbio, 7, 2016
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5HUA
 | | Structure of C. glabrata FKBP12-FK506 complex | | Descriptor: | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, FK506-binding protein 1 | | Authors: | Schumacher, M.A. | | Deposit date: | 2016-01-27 | | Release date: | 2016-09-14 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.
Mbio, 7, 2016
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5HTG
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5I98
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3PM1
 | | Structure of QacR E90Q bound to Ethidium | | Descriptor: | ETHIDIUM, HTH-type transcriptional regulator qacR, SULFATE ION | | Authors: | Schumacher, M.A. | | Deposit date: | 2010-11-15 | | Release date: | 2011-07-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A single acidic residue can guide binding site selection but does not govern QacR cationic-drug affinity.
Plos One, 6, 2011
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5HSZ
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5U1J
 | | Structure of pNOB8 ParA bound to nonspecific DNA | | Descriptor: | DNA (5'-D(*CP*GP*TP*GP*TP*AP*AP*TP*GP*AP*CP*GP*CP*CP*GP*GP*CP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*CP*GP*CP*CP*GP*GP*CP*GP*TP*CP*AP*TP*GP*AP*CP*AP*CP*G)-3'), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Schumacher, M.A. | | Deposit date: | 2016-11-28 | | Release date: | 2017-04-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structures of partition protein ParA with nonspecific DNA and ParB effector reveal molecular insights into principles governing Walker-box DNA segregation.
Genes Dev., 31, 2017
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