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5AHK
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BU of 5ahk by Molmil
Crystal structure of acetohydroxy acid synthase Pf5 from Pseudomonas protegens
Descriptor: ACETOLACTATE SYNTHASE II, LARGE SUBUNIT, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Dobritzsch, D, Loschonsky, S, Mueller, M, Schneider, G.
Deposit date:2015-02-06
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The Crystal Structure of the Acetohydroxy Acid Synthase Pf5 from Pseudomonas Protegens
To be Published
1NGS
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BU of 1ngs by Molmil
COMPLEX OF TRANSKETOLASE WITH THIAMIN DIPHOSPHATE, CA2+ AND ACCEPTOR SUBSTRATE ERYTHROSE-4-PHOSPHATE
Descriptor: CALCIUM ION, ERYTHOSE-4-PHOSPHATE, THIAMINE DIPHOSPHATE, ...
Authors:Nilsson, U, Lindqvist, Y, Schneider, G.
Deposit date:1996-09-25
Release date:1997-02-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Examination of substrate binding in thiamin diphosphate-dependent transketolase by protein crystallography and site-directed mutagenesis.
J.Biol.Chem., 272, 1997
1DAG
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BU of 1dag by Molmil
DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID AND 5'-ADENOSYL-METHYLENE-TRIPHOSPHATE
Descriptor: 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, DETHIOBIOTIN SYNTHETASE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Huang, W, Jia, J, Schneider, G, Lindqvist, Y.
Deposit date:1995-05-08
Release date:1996-06-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Biochemistry, 34, 1995
1DAE
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BU of 1dae by Molmil
DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 3-(1-AMINOETHYL) NONANEDIOIC ACID
Descriptor: 3-(1-AMINOETHYL)NONANEDIOIC ACID, DETHIOBIOTIN SYNTHETASE
Authors:Huang, W, Jia, J, Schneider, G, Lindqvist, Y.
Deposit date:1995-05-08
Release date:1996-06-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Biochemistry, 34, 1995
1DAH
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BU of 1dah by Molmil
DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7,8-DIAMINO-NONANOIC ACID, 5'-ADENOSYL-METHYLENE-TRIPHOSPHATE, AND MANGANESE
Descriptor: 7,8-DIAMINO-NONANOIC ACID, DETHIOBIOTIN SYNTHETASE, MANGANESE (II) ION, ...
Authors:Huang, W, Jia, J, Schneider, G, Lindqvist, Y.
Deposit date:1995-05-08
Release date:1996-06-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Biochemistry, 34, 1995
1DAI
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BU of 1dai by Molmil
DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID
Descriptor: 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, DETHIOBIOTIN SYNTHETASE
Authors:Huang, W, Jia, J, Schneider, G, Lindqvist, Y.
Deposit date:1995-05-08
Release date:1996-06-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Biochemistry, 34, 1995
1DAF
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BU of 1daf by Molmil
DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, ADP, AND CALCIUM
Descriptor: 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Huang, W, Jia, J, Schneider, G, Lindqvist, Y.
Deposit date:1995-05-08
Release date:1996-06-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Biochemistry, 34, 1995
1DAD
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BU of 1dad by Molmil
DETHIOBIOTIN SYNTHETASE COMPLEXED WITH ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DETHIOBIOTIN SYNTHETASE
Authors:Huang, W, Jia, J, Schneider, G, Lindqvist, Y.
Deposit date:1995-05-08
Release date:1996-06-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate.
Biochemistry, 34, 1995
5I7R
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BU of 5i7r by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 2 [3-(3-([1,1'-biphenyl]-3-yl)ureido)benzoic acid]
Descriptor: 3-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}benzoic acid, ACETATE ION, O-phosphoserine sulfhydrylase, ...
Authors:Schnell, R, Maric, S, Schneider, G.
Deposit date:2016-02-18
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I7H
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BU of 5i7h by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 6 [3-(3-(4-Bromophenyl)ureido)benzoic acid]
Descriptor: 3-{[(4-bromophenyl)carbamoyl]amino}benzoic acid, CHLORIDE ION, O-phosphoserine sulfhydrylase, ...
Authors:Schnell, R, Maric, S, Schneider, G.
Deposit date:2016-02-17
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I7O
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BU of 5i7o by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 7 [3-(3-(4-Chlorophenyl)ureido)benzoic acid]
Descriptor: 3-{[(4-chlorophenyl)carbamoyl]amino}benzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Schnell, R, Maric, S, Schneider, G.
Deposit date:2016-02-18
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I6D
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BU of 5i6d by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 5 [3-(3-(p-Tolyl)ureido) benzoic acid]
Descriptor: 3-{[(4-methylphenyl)carbamoyl]amino}benzoic acid, GLYCEROL, O-phosphoserine sulfhydrylase, ...
Authors:Schnell, R, Maric, S, Schneider, G.
Deposit date:2016-02-16
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I7A
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BU of 5i7a by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 1 [3-(3-(3,4-Dichlorophenyl)ureido)benzoic acid]
Descriptor: 3-{[(3,4-dichlorophenyl)carbamoyl]amino}benzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Schnell, R, Maric, S, Schneider, G.
Deposit date:2016-02-17
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5IW8
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BU of 5iw8 by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 4 [5-(3-([1,1'-Biphenyl]-3-yl)ureido)-2-hydroxybenzoic acid]
Descriptor: 5-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}-2-hydroxybenzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Brunner, K, Schnell, R, Schneider, G.
Deposit date:2016-03-22
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5IWC
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BU of 5iwc by Molmil
Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 3 [4-(3-([1,1'-Biphenyl]-3-yl)ureido)-2-hydroxybenzoic acid]
Descriptor: 4-{[([1,1'-biphenyl]-3-yl)carbamoyl]amino}-2-hydroxybenzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Schnell, R, Maric, S, Lindqvist, Y, Schneider, G.
Deposit date:2016-03-22
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
1QPB
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BU of 1qpb by Molmil
PYRUVATE DECARBOYXLASE FROM YEAST (FORM B) COMPLEXED WITH PYRUVAMIDE
Descriptor: MAGNESIUM ION, PYRUVAMIDE, PYRUVATE DECARBOXYLASE (FORM B), ...
Authors:Lu, G, Dobritzsch, D, Schneider, G.
Deposit date:1999-11-26
Release date:2000-02-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structural Basis of Substrate Activation in Yeast Pyruvate Decarboxylase a Crystallographic and Kinetic Study
Eur.J.Biochem., 267, 2000
3CQ5
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BU of 3cq5 by Molmil
Histidinol-phosphate aminotransferase from Corynebacterium glutamicum in complex with PMP
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Histidinol-phosphate aminotransferase, SULFATE ION, ...
Authors:Sandalova, T, Marienhagen, J, Schneider, G.
Deposit date:2008-04-02
Release date:2008-07-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum
Acta Crystallogr.,Sect.D, 64, 2008
3CQ4
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BU of 3cq4 by Molmil
Histidinol-phosphate aminotransferase from Corynebacterium glutamicum
Descriptor: ACETATE ION, Histidinol-phosphate aminotransferase
Authors:Sandalova, T, Marienhagen, J, Schneider, G.
Deposit date:2008-04-02
Release date:2008-07-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum
Acta Crystallogr.,Sect.D, 64, 2008
3CQ6
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BU of 3cq6 by Molmil
Histidinol-phosphate aminotransferase from Corynebacterium glutamicum holo-form (PLP covalently bound )
Descriptor: Histidinol-phosphate aminotransferase, PHOSPHATE ION
Authors:Sandalova, T, Marienhagen, J, Schneider, G.
Deposit date:2008-04-02
Release date:2008-07-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum
Acta Crystallogr.,Sect.D, 64, 2008
3DKI
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BU of 3dki by Molmil
2.1 A X-ray structure of CysM (Rv1336) from Mycobacterium tuberculosis an O-phosphoserine dependent cysteine synthase
Descriptor: Cysteine synthase B, SODIUM ION
Authors:Agren, D, Schnell, R, Schneider, G.
Deposit date:2008-06-25
Release date:2008-09-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cysteine Synthase (CysM) of Mycobacterium tuberculosis Is an O-Phosphoserine Sulfhydrylase: EVIDENCE FOR AN ALTERNATIVE CYSTEINE BIOSYNTHESIS PATHWAY IN MYCOBACTERIA
J.Biol.Chem., 283, 2008
3PBC
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BU of 3pbc by Molmil
Peptidase module of the peptidoglycan hydrolase RipA (Rv1477) from Mycobacterium tuberculosis at 1.38 resolution
Descriptor: INVASION PROTEIN
Authors:Schnell, R, Both, D, Schneider, G.
Deposit date:2010-10-20
Release date:2011-08-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Peptidoglycan Remodeling in Mycobacterium tuberculosis: Comparison of Structures and Catalytic Activities of RipA and RipB.
J.Mol.Biol., 413, 2011
3PBI
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BU of 3pbi by Molmil
Structure of the peptidoglycan hydrolase RipB (Rv1478) from Mycobacterium tuberculosis at 1.6 resolution
Descriptor: INVASION PROTEIN
Authors:Schnell, R, Both, D, Schneider, G.
Deposit date:2010-10-20
Release date:2011-08-31
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Peptidoglycan Remodeling in Mycobacterium tuberculosis: Comparison of Structures and Catalytic Activities of RipA and RipB.
J.Mol.Biol., 413, 2011
3FGP
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BU of 3fgp by Molmil
2.05 a Crystal Structure of CysM from Mycobacterium Tuberculosis - Open and Closed Conformations
Descriptor: Cysteine synthase B
Authors:Agren, D, Schnell, R, Schneider, G.
Deposit date:2008-12-08
Release date:2008-12-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The C-terminal of CysM from Mycobacterium tuberculosis protects the aminoacrylate intermediate and is involved in sulfur donor selectivity
Febs Lett., 583, 2009
3QZE
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BU of 3qze by Molmil
Crystal Structure of DapA (PA1010) at 1.6 A resolution
Descriptor: CHLORIDE ION, Dihydrodipicolinate synthase
Authors:Schnell, R, Sandalova, T, Schneider, G.
Deposit date:2011-03-05
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Tetrahydrodipicolinate N-succinyltransferase and dihydrodipicolinate synthase from Pseudomonas aeruginosa: structure analysis and gene deletion.
Plos One, 7, 2012
2VHW
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BU of 2vhw by Molmil
Crystal structure of holo L-alanine dehydrogenase from Mycobacterium tuberculosis in the open and closed conformation
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ALANINE DEHYDROGENASE, MAGNESIUM ION
Authors:Agren, D, Schneider, G.
Deposit date:2007-11-26
Release date:2008-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-Dimensional Structures of Apo- and Holo-L-Alanine Dehydrogenase from Mycobacterium Tuberculosis Reveal Conformational Changes Upon Coenzyme Binding.
J.Mol.Biol., 377, 2008

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