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2V7C
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BU of 2v7c by Molmil
Crystal Structure of Rev-Erb beta
Descriptor: ORPHAN NUCLEAR RECEPTOR NR1D2
Authors:Woo, E.-J, Jeong, D.G, Lim, M.-Y, Kim, S.J, Ryu, S.E.
Deposit date:2007-07-29
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insight Into the Constitutive Repression Function of the Nuclear Receptor Rev-Erbbeta
J.Mol.Biol., 373, 2007
7XC0
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BU of 7xc0 by Molmil
Crystal structure of Human RPTPH
Descriptor: PHOSPHATE ION, Receptor-type tyrosine-protein phosphatase H
Authors:Kim, M, Ryu, S.E.
Deposit date:2022-03-22
Release date:2022-07-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Crystal structure of the catalytic domain of human RPTPH.
Acta Crystallogr.,Sect.F, 78, 2022
7E73
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BU of 7e73 by Molmil
Crystal structure of human ERK2 mutant (Y36H)
Descriptor: Mitogen-activated protein kinase 1, SULFATE ION
Authors:Park, Y.S, Kim, M, Ryu, S.E.
Deposit date:2021-02-25
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural mechanism of inhibitor-resistance by ERK2 mutations
Biodesign, 9, 2021
7E75
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BU of 7e75 by Molmil
Crystal structure of human ERK2 mutant (G37C)
Descriptor: Mitogen-activated protein kinase 1
Authors:Park, Y.S, Kim, M, Ryu, S.E.
Deposit date:2021-02-25
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.481 Å)
Cite:Structural mechanism of inhibitor-resistance by ERK2 mutations
Biodesign, 9, 2021
4IKC
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BU of 4ikc by Molmil
Crystal Structure of catalytic domain of PTPRQ
Descriptor: CHLORIDE ION, Phosphotidylinositol phosphatase PTPRQ, SULFATE ION
Authors:Yu, K.R, Ryu, S.E, Kim, S.J.
Deposit date:2012-12-26
Release date:2013-07-31
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates
Acta Crystallogr.,Sect.D, 69, 2013
2ESB
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BU of 2esb by Molmil
Crystal structure of human DUSP18
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, Dual specificity protein phosphatase 18
Authors:Kim, S.J, Ryu, S.E, Jeong, D.G, Cho, Y.H, Yoon, T.S, Kim, J.H.
Deposit date:2005-10-25
Release date:2006-06-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human DSP18, a member of the dual-specificity protein tyrosine phosphatase family.
Acta Crystallogr.,Sect.D, 62, 2006
2G6Z
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BU of 2g6z by Molmil
Crystal structure of human DUSP5
Descriptor: Dual specificity protein phosphatase 5, SULFATE ION
Authors:Kim, S.J, Ryu, S.E.
Deposit date:2006-02-26
Release date:2007-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase
Proteins, 66, 2007
2GWO
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BU of 2gwo by Molmil
crystal structure of TMDP
Descriptor: Dual specificity protein phosphatase 13
Authors:Kim, S.J, Ryu, S.E, Kim, J.H.
Deposit date:2006-05-05
Release date:2007-03-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human TMDP, a testis-specific dual specificity protein phosphatase: implications for substrate specificity
Proteins, 66, 2007
1YZ4
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BU of 1yz4 by Molmil
Crystal structure of DUSP15
Descriptor: SULFATE ION, dual specificity phosphatase-like 15 isoform a, octyl beta-D-glucopyranoside
Authors:Kim, S.J, Ryu, S.E, Jeong, D.G, Yoon, T.S, Kim, J.H, Cho, Y.H, Jeong, S.K, Lee, J.W, Son, J.H.
Deposit date:2005-02-28
Release date:2005-11-01
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the catalytic domain of human VHY, a dual-specificity protein phosphatase
Proteins, 61, 2005
1ZZW
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BU of 1zzw by Molmil
Crystal Structure of catalytic domain of Human MAP Kinase Phosphatase 5
Descriptor: 1,2-ETHANEDIOL, Dual specificity protein phosphatase 10, SULFATE ION
Authors:Jeong, D.G, Yoon, T.S, Kim, J.H, Shim, M.Y, Jeong, S.K, Son, J.H, Ryu, S.E, Kim, S.J.
Deposit date:2005-06-14
Release date:2006-07-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the Catalytic Domain of Human MAP Kinase Phosphatase 5: Structural Insight into Constitutively Active Phosphatase.
J.Mol.Biol., 360, 2006
1IY7
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BU of 1iy7 by Molmil
Crystal Structure of CPA and sulfamide-based inhibitor complex
Descriptor: Carboxypeptidase A, PHENYLALANINE-N-SULFONAMIDE, ZINC ION
Authors:Kim, S.J, Woo, J.R, Park, J.D, Kim, D.H, Ryu, S.E.
Deposit date:2002-07-24
Release date:2003-01-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sulfamide-Based Inhibitors for Carboxypeptidase A. Novel Type Transition State Analogue Inhibitors for Zinc Proteases
J.Med.Chem., 45, 2002
3HB1
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BU of 3hb1 by Molmil
Crystal structure of ed-eya2 complexed with Alf3
Descriptor: ALUMINUM FLUORIDE, Eyes absent homolog 2 (Drosophila), MAGNESIUM ION
Authors:Jung, S.K, Jeong, D.G, Ryu, S.E, Kim, S.J.
Deposit date:2009-05-03
Release date:2009-12-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor
Faseb J., 24, 2010
3HB0
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BU of 3hb0 by Molmil
Structure of edeya2 complexed with bef3
Descriptor: BERYLLIUM TRIFLUORIDE ION, Eyes absent homolog 2 (Drosophila), MAGNESIUM ION
Authors:Jung, S.K, Jeong, D.G, Ryu, S.E, Kim, S.J.
Deposit date:2009-05-03
Release date:2009-12-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor
Faseb J., 24, 2010
3LJ8
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BU of 3lj8 by Molmil
Crystal Structure of MKP-4
Descriptor: Tyrosine-protein phosphatase
Authors:Jeong, D.G, Yoon, T.S, Jung, S.-K, Park, H.S, Ryu, S.E, Kim, S.J.
Deposit date:2010-01-26
Release date:2010-12-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Exploring binding sites other than the catalytic core in the crystal structure of the catalytic domain of MKP-4
Acta Crystallogr.,Sect.D, 67, 2011
5Y15
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BU of 5y15 by Molmil
Crystal structure of human DUSP28
Descriptor: Dual specificity phosphatase 28, PHOSPHATE ION
Authors:Ku, B, Hong, W, Kim, S.J, Ryu, S.E.
Deposit date:2017-07-19
Release date:2017-11-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28
PLoS ONE, 12, 2017
5Y16
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BU of 5y16 by Molmil
Crystal structure of human DUSP28(Y102H)
Descriptor: CHLORIDE ION, Dual specificity phosphatase 28, PHOSPHATE ION
Authors:Ku, B, Kim, M, Kim, S.J, Ryu, S.E.
Deposit date:2017-07-19
Release date:2017-11-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28
PLoS ONE, 12, 2017
2NT2
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BU of 2nt2 by Molmil
Crystal Structure of Slingshot phosphatase 2
Descriptor: Protein phosphatase Slingshot homolog 2, SULFATE ION
Authors:Jung, S.K, Jeong, D.G, Yoon, T.S, Kim, J.H, Ryu, S.E, Kim, S.J.
Deposit date:2006-11-06
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human slingshot phosphatase 2.
Proteins, 68, 2007
5XJV
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BU of 5xjv by Molmil
Two intermediate states of conformation switch in dual specificity phosphatase 13a
Descriptor: Dual specificity protein phosphatase 13 isoform A, PHOSPHATE ION
Authors:Wei, C.H, Min, H.G, Chun, H.J, Ryu, S.E.
Deposit date:2017-05-04
Release date:2018-04-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Two intermediate states of the conformational switch in dual specificity phosphatase 13a
Pharmacol. Res., 128, 2018
1ATU
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BU of 1atu by Molmil
UNCLEAVED ALPHA-1-ANTITRYPSIN
Descriptor: ALPHA-1-ANTITRYPSIN
Authors:Ryu, S.-E, Choi, H.-J.
Deposit date:1997-05-11
Release date:1997-08-20
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A.
Structure, 4, 1996
1PRX
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BU of 1prx by Molmil
HORF6 A NOVEL HUMAN PEROXIDASE ENZYME
Descriptor: HORF6
Authors:Choi, H.-J, Kang, S.W, Yang, C.-H, Rhee, S.G, Ryu, S.-E.
Deposit date:1998-04-03
Release date:1998-06-17
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a novel human peroxidase enzyme at 2.0 A resolution.
Nat.Struct.Biol., 5, 1998
1I7F
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BU of 1i7f by Molmil
CRYSTAL STRUCTURE OF THE HSP33 DOMAIN WITH CONSTITUTIVE CHAPERONE ACTIVITY
Descriptor: GLYCEROL, HEAT SHOCK PROTEIN 33, SULFATE ION
Authors:Kim, S.-J, Jeong, D.-G, Chi, S.-W, Lee, J.-S, Ryu, S.-E.
Deposit date:2001-03-09
Release date:2001-05-09
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of proteolytic fragments of the redox-sensitive Hsp33 with constitutive chaperone activity
Nat.Struct.Biol., 8, 2001
1IZ3
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BU of 1iz3 by Molmil
Dimeric structure of FIH (Factor inhibiting HIF)
Descriptor: FIH, SULFATE ION
Authors:Lee, C, Kim, S.-J, Jeong, D.-G, Lee, S.M, Ryu, S.-E.
Deposit date:2002-09-19
Release date:2003-06-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau.
J.Biol.Chem., 278, 2003
1KU0
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BU of 1ku0 by Molmil
Structure of the Bacillus stearothermophilus L1 lipase
Descriptor: CALCIUM ION, L1 lipase, ZINC ION
Authors:Jeong, S.-T, Kim, H.-K, Kim, S.-J, Chi, S.-W, Pan, J.-G, Oh, T.-K, Ryu, S.-E.
Deposit date:2002-01-18
Release date:2002-08-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel zinc-binding center and a temperature switch in the Bacillus stearothermophilus L1 lipase.
J.Biol.Chem., 277, 2002
5X8M
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BU of 5x8m by Molmil
PD-L1 in complex with durvalumab
Descriptor: Programmed cell death 1 ligand 1, durvalumab heavy chain, durvalumab light chain
Authors:Heo, Y.S, Lee, H.T.
Deposit date:2017-03-03
Release date:2017-08-16
Method:X-RAY DIFFRACTION (2.661 Å)
Cite:Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab
Sci Rep, 7, 2017
5X8L
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BU of 5x8l by Molmil
PD-L1 in complex with atezolizumab
Descriptor: Programmed cell death 1 ligand 1, atezolizumab heavy chain, atezolizumab light chain
Authors:Heo, Y.S, Lee, H.T.
Deposit date:2017-03-03
Release date:2017-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab
Sci Rep, 7, 2017

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