8GXQ
| PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y. | 登録日 | 2022-09-21 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (5.04 Å) | 主引用文献 | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
|
|
8IUE
| RNA polymerase III pre-initiation complex melting complex 1 | 分子名称: | DNA (74-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | 著者 | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | 登録日 | 2023-03-24 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure of the SNAPc-bound RNA polymerase III preinitiation complex. Cell Res., 33, 2023
|
|
8IUH
| RNA polymerase III pre-initiation complex open complex 1 | 分子名称: | DNA (81-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | 著者 | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | 登録日 | 2023-03-24 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the SNAPc-bound RNA polymerase III preinitiation complex. Cell Res., 33, 2023
|
|
6ISU
| Crystal structure of Lys27-linked di-ubiquitin in complex with its selective interacting protein UCHL3 | 分子名称: | Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L3 | 著者 | Ding, S, Pan, M, Zheng, Q, Ren, Y, Hong, D. | 登録日 | 2018-11-19 | 公開日 | 2019-02-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.866 Å) | 主引用文献 | Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains. Angew. Chem. Int. Ed. Engl., 58, 2019
|
|
8ITY
| human RNA polymerase III pre-initiation complex closed DNA 1 | 分子名称: | DNA (82-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | 著者 | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | 登録日 | 2023-03-23 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the SNAPc-bound RNA polymerase III preinitiation complex. Cell Res., 33, 2023
|
|
8GXS
| PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X. | 登録日 | 2022-09-21 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
|
|
7YCX
| The structure of INTAC-PEC complex | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. | 登録日 | 2022-07-02 | 公開日 | 2023-03-15 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Structural basis of INTAC-regulated transcription. Protein Cell, 14, 2023
|
|
7V6G
| Structure of Candida albicans Fructose-1,6-bisphosphate aldolase mutation C157S with CN39 | 分子名称: | 1,2-ETHANEDIOL, Fructose-bisphosphate aldolase, ZINC ION, ... | 著者 | Cao, H, Huang, Y, Chen, H, Wan, C, Ren, Y, Wan, J. | 登録日 | 2021-08-20 | 公開日 | 2022-02-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.343 Å) | 主引用文献 | Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis. J.Med.Chem., 65, 2022
|
|
7V6F
| Structure of Candida albicans Fructose-1,6-bisphosphate aldolase complexed with G3P | 分子名称: | Fructose-bisphosphate aldolase, GLYCERALDEHYDE-3-PHOSPHATE, ZINC ION | 著者 | Hongxuan, C, Huang, Y, Han, C, Chen, W, Ren, Y, Wan, J. | 登録日 | 2021-08-20 | 公開日 | 2022-02-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis. J.Med.Chem., 65, 2022
|
|
7XI6
| Crystal structure of C56 from pSSVi | 分子名称: | C56 | 著者 | Zhang, Z.F, Ren, Y, Chen, Y.Y, Zhang, X.W, Dong, Y.H, Gong, Y, Cao, P, Huang, L. | 登録日 | 2022-04-12 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Characterization of the AbrB-like protein C56 conserved in a novel family of integrated genetic elements in Sulfolobales To Be Published
|
|
8IQ4
| Cryo-EM structure of Carboprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | 登録日 | 2023-03-15 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity. Nat Commun, 14, 2023
|
|
8IQ6
| Cryo-EM structure of Latanoprost-bound prostaglandin-F2-alpha receptor-miniGq-Nb35 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Lv, X, Gao, K, Nie, J, Zhang, X, Zhang, S, Ren, Y, Li, Q, Huang, J, Liu, L, Zhang, X, Sun, X, Zhang, W, Liu, X. | 登録日 | 2023-03-15 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of human prostaglandin F 2 alpha receptor reveal the mechanism of ligand and G protein selectivity. Nat Commun, 14, 2023
|
|
7XZG
| High resolution crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Candida albicans complexed with NAD+ | 分子名称: | 1,2-ETHANEDIOL, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Cao, H, Meng, J, Ren, Y, Wan, J. | 登録日 | 2022-06-02 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.879 Å) | 主引用文献 | High resolution crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Candida albicans complexed with NAD+ To Be Published
|
|
7DN3
| Structure of Human RNA Polymerase III elongation complex | 分子名称: | DNA (5'-D(P*TP*CP*GP*TP*CP*TP*GP*AP*TP*CP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*CP*GP*AP*GP*AP*TP*CP*AP*GP*AP*CP*GP*AP*GP*AP*TP*CP*GP*GP*G)-3'), DNA-directed RNA polymerase III subunit RPC1, ... | 著者 | Li, L, Yu, Z, Zhao, D, Ren, Y, Hou, H, Xu, Y. | 登録日 | 2020-12-08 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of human RNA polymerase III elongation complex. Cell Res., 31, 2021
|
|
7DU2
| RNA polymerase III EC complex in post-translocation state | 分子名称: | DNA (5'-D(P*GP*TP*CP*TP*GP*AP*TP*CP*TP*CP*GP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*CP*GP*AP*GP*AP*TP*CP*AP*GP*AP*CP*GP*AP*GP*AP*T)-3'), DNA-directed RNA polymerase III subunit RPC1, ... | 著者 | Li, L, Yu, Z, Zhao, D, Ren, Y, Hou, H, Xu, Y. | 登録日 | 2021-01-07 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Structure of human RNA polymerase III elongation complex. Cell Res., 31, 2021
|
|
5GL8
| |
8WKH
| Crystal structure of group 13 allergen from Blomia tropicalis | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Fatty acid-binding protein | 著者 | Zhu, K.L, Gong, Y, Cui, Y.B. | 登録日 | 2023-09-27 | 公開日 | 2023-11-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Immunobiological properties and structure analysis of group 13 allergen from Blomia tropicalis and its IgE-mediated cross-reactivity. Int.J.Biol.Macromol., 254, 2023
|
|
8JMT
| Structure of the adhesion GPCR ADGRL3 in the apo state | 分子名称: | Adhesion G protein-coupled receptor L3,Soluble cytochrome b562 | 著者 | Tao, Y, Guo, Q, He, B, Zhong, Y. | 登録日 | 2023-06-05 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
|
|
8J7E
| |
8JJO
| Cryo-EM structure of the beta2AR-mBRIL/1b3 Fab/Glue complex with an antagonist | 分子名称: | (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, Beta-2 adrenergic receptor,Beta-2 adrenergic receptor,Soluble cytochrome b562 | 著者 | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | 登録日 | 2023-05-31 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
|
|
8JJL
| cryo-EM structure of the beta2-AR-mBRIL/1b3 Fab/Glue complex with a full agonist | 分子名称: | Beta-2 adrenergic receptor,Soluble cytochrome b562, Olodaterol | 著者 | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | 登録日 | 2023-05-30 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
|
|
8JJ8
| Cryo-EM structure of the beta2AR-mBRIL/1b3 Fab/Glue complex with a partial agonist | 分子名称: | Beta-2 adrenergic receptor,Soluble cytochrome b562, ~{N}-[5-[(1~{R})-2-[[(2~{R})-1-(4-methoxyphenyl)propan-2-yl]amino]-1-oxidanyl-ethyl]-2-oxidanyl-phenyl]methanamide | 著者 | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | 登録日 | 2023-05-29 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
|
|
8JBA
| |
8K0C
| |
8K0D
| |