5V7V
 
 | | Cryo-EM structure of ERAD-associated E3 ubiquitin-protein ligase component HRD3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ERAD-associated E3 ubiquitin-protein ligase component HRD3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Mi, W, Schoebel, S, Stein, A, Rapoport, T.A, Liao, M. | | Deposit date: | 2017-03-20 | | Release date: | 2017-08-16 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
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5V6P
 | | CryoEM structure of the ERAD-associated E3 ubiquitin-protein ligase HRD1 | | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1 | | Authors: | Schoebel, S, Mi, W, Stein, A, Rapoport, T.A, Liao, M. | | Deposit date: | 2017-03-17 | | Release date: | 2017-08-16 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
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7R9D
 | | Crystal structure of Nb_0 in complex with Fab_8D3 | | Descriptor: | Fab 8D3 heavy chain, Fab 8D3 light chain, Nanobody N0 | | Authors: | Wu, X.D, Rapoport, T.A. | | Deposit date: | 2021-06-29 | | Release date: | 2021-10-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Cryo-EM structure determination of small proteins by nanobody-binding scaffolds (Legobodies).
Proc.Natl.Acad.Sci.USA, 118, 2021
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7RXD
 | | CryoEM structure of RBD domain of COVID-19 in complex with Legobody | | Descriptor: | Fab_8D3_2 heavy chain, Fab_8D3_2 light chain, Maltodextrin-binding protein,Immunoglobulin G-binding protein A,Immunoglobulin G-binding protein G, ... | | Authors: | Wu, X.D, Rapoport, T.A. | | Deposit date: | 2021-08-22 | | Release date: | 2021-10-06 | | Last modified: | 2021-10-20 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure determination of small proteins by nanobody-binding scaffolds (Legobodies).
Proc.Natl.Acad.Sci.USA, 118, 2021
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7RXC
 | | CryoEM structure of KDELR with Legobody | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ER lumen protein-retaining receptor 2, Fab_8D3_2 heavy chain, ... | | Authors: | Wu, X.D, Rapoport, T.A. | | Deposit date: | 2021-08-22 | | Release date: | 2021-10-06 | | Last modified: | 2021-10-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structure determination of small proteins by nanobody-binding scaffolds (Legobodies).
Proc.Natl.Acad.Sci.USA, 118, 2021
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3J45
 | | Structure of a non-translocating SecY protein channel with the 70S ribosome | | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L23, 50S ribosomal protein L24, ... | | Authors: | Menetret, J.F, Park, E, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A, Akey, C.W. | | Deposit date: | 2013-06-18 | | Release date: | 2013-10-23 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Structure of the SecY channel during initiation of protein translocation.
Nature, 506, 2013
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3J46
 | | Structure of the SecY protein translocation channel in action | | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L23P, ... | | Authors: | Akey, C.W, Park, E, Menetret, J.F, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A. | | Deposit date: | 2013-06-18 | | Release date: | 2013-10-23 | | Last modified: | 2019-07-03 | | Method: | ELECTRON MICROSCOPY (10.1 Å) | | Cite: | Structure of the SecY channel during initiation of protein translocation.
Nature, 506, 2013
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3KP9
 | | Structure of a bacterial homolog of vitamin K epoxide reductase | | Descriptor: | MERCURY (II) ION, UBIQUINONE-10, VKORC1/thioredoxin domain protein | | Authors: | Li, W, Schulman, S, Dutton, R.J, Boyd, D, Beckwith, J, Rapoport, T.A. | | Deposit date: | 2009-11-16 | | Release date: | 2010-02-09 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structure of a bacterial homologue of vitamin K epoxide reductase.
Nature, 463, 2010
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3KP8
 | | The thioredoxin-like domain of a VKOR homolog from Synechococcus sp. | | Descriptor: | VKORC1/thioredoxin domain protein | | Authors: | Li, W, Schulman, S, Dutton, R.J, Boyd, D, Beckwith, J, Rapoport, T.A. | | Deposit date: | 2009-11-15 | | Release date: | 2010-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Structure of a bacterial homologue of vitamin K epoxide reductase.
Nature, 463, 2010
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3DL8
 | | Structure of the complex of aquifex aeolicus SecYEG and bacillus subtilis SecA | | Descriptor: | Preprotein translocase subunit secY, Protein translocase subunit secA, Protein-export membrane protein secG, ... | | Authors: | Nam, Y, Zimmer, J, Rapoport, T.A. | | Deposit date: | 2008-06-26 | | Release date: | 2008-12-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (7.5 Å) | | Cite: | Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature, 455, 2008
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3DIN
 | | Crystal structure of the protein-translocation complex formed by the SecY channel and the SecA ATPase | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | Authors: | Zimmer, J, Nam, Y, Rapoport, T.A. | | Deposit date: | 2008-06-20 | | Release date: | 2008-10-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature, 455, 2008
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6VK3
 | | CryoEM structure of Hrd3/Yos9 complex | | Descriptor: | Hrd3, Protein OS-9 homolog | | Authors: | Wu, X, Rapoport, T.A. | | Deposit date: | 2020-01-18 | | Release date: | 2020-04-29 | | Last modified: | 2020-05-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
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6VJZ
 | | CryoEM structure of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology | | Descriptor: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | | Authors: | Wu, X, Rapoport, T.A. | | Deposit date: | 2020-01-18 | | Release date: | 2020-04-29 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
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6VK1
 | | CryoEM structure of Hrd1/Hrd3 part from Hrd1-Usa1/Der1/Hrd3 complex | | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 | | Authors: | Wu, X, Rapoport, T.A. | | Deposit date: | 2020-01-18 | | Release date: | 2020-04-29 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
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6VK0
 | | CryoEM structure of Hrd1-Usa1/Der1/Hrd3 of the flipped topology | | Descriptor: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | | Authors: | Wu, X, Rapoport, T.A. | | Deposit date: | 2020-01-18 | | Release date: | 2020-04-29 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
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6VJY
 | | Cryo-EM structure of Hrd1/Hrd3 monomer | | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 | | Authors: | Wu, X, Rapoport, T.A. | | Deposit date: | 2020-01-18 | | Release date: | 2020-04-29 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.
Science, 368, 2020
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1RH5
 | | The structure of a protein conducting channel | | Descriptor: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | | Authors: | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | | Deposit date: | 2003-11-13 | | Release date: | 2004-01-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | X-ray structure of a protein-conducting channel
Nature, 427, 2004
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1RHZ
 | | The structure of a protein conducting channel | | Descriptor: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | | Authors: | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | | Deposit date: | 2003-11-15 | | Release date: | 2004-01-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | X-ray structure of a protein-conducting channel.
Nature, 427, 2004
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1TF2
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1TF5
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1T1L
 | | Crystal structure of the long-chain fatty acid transporter FadL | | Descriptor: | LAURYL DIMETHYLAMINE-N-OXIDE, Long-chain fatty acid transport protein | | Authors: | van den Berg, B, Black, P.N, Clemons Jr, W.M, Rapoport, T.A. | | Deposit date: | 2004-04-16 | | Release date: | 2004-06-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of the long-chain fatty acid transporter FadL.
Science, 304, 2004
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1T16
 | | Crystal structure of the bacterial fatty acid transporter FadL from Escherichia coli | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, COPPER (II) ION, LAURYL DIMETHYLAMINE-N-OXIDE, ... | | Authors: | van den Berg, B, Black, P.N, Clemons Jr, W.M, Rapoport, T.A. | | Deposit date: | 2004-04-15 | | Release date: | 2004-06-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of the long-chain fatty acid transporter FadL.
Science, 304, 2004
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7T9X
 | | Saccharomyces cerevisiae Pex12 RING domain | | Descriptor: | Peroxisome assembly protein 12, ZINC ION | | Authors: | Feng, P, Rapoport, T. | | Deposit date: | 2021-12-20 | | Release date: | 2022-06-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel.
Nature, 607, 2022
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7T92
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3QNU
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