1TUI
 
 | | INTACT ELONGATION FACTOR TU IN COMPLEX WITH GDP | | 分子名称: | ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Polekhina, G, Thirup, S, Kjeldgaard, M, Nissen, P, Lippmann, C, Nyborg, J. | | 登録日 | 1996-05-23 | | 公開日 | 1997-06-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Helix unwinding in the effector region of elongation factor EF-Tu-GDP.
Structure, 4, 1996
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1Z0M
 | | the glycogen-binding domain of the AMP-activated protein kinase beta1 subunit | | 分子名称: | 5'-AMP-activated protein kinase, beta-1 subunit, Cycloheptakis-(1-4)-(alpha-D-glucopyranose) | | 著者 | Polekhina, G, Gupta, A, van Denderen, B.J, Feil, S.C, Kemp, B.E, Stapleton, D, Parker, M.W. | | 登録日 | 2005-03-02 | | 公開日 | 2005-10-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Structural Basis for Glycogen Recognition by AMP-Activated Protein Kinase.
Structure, 13, 2005
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1Z0N
 | | the glycogen-binding domain of the AMP-activated protein kinase | | 分子名称: | 5'-AMP-activated protein kinase, beta-1 subunit, Cycloheptakis-(1-4)-(alpha-D-glucopyranose) | | 著者 | Polekhina, G, Gupta, A, van Denderen, B.J, Feil, S.C, Kemp, B.E, Stapleton, D, Parker, M.W. | | 登録日 | 2005-03-02 | | 公開日 | 2005-10-25 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Structural Basis for Glycogen Recognition by AMP-Activated Protein Kinase.
Structure, 13, 2005
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4GEJ
 | | N-terminal domain of VDUP-1 | | 分子名称: | CALCIUM ION, Thioredoxin-interacting protein | | 著者 | Polekhina, G, Kok, S.F, Ascher, D.B, Waltham, M. | | 登録日 | 2012-08-02 | | 公開日 | 2013-02-27 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the N-terminal domain of human thioredoxin-interacting protein.
Acta Crystallogr.,Sect.D, 69, 2013
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4GEI
 | | N-terminal domain of VDUP-1 | | 分子名称: | Thioredoxin-interacting protein | | 著者 | Polekhina, G, Kok, S.F, Ascher, D.B, Waltham, M. | | 登録日 | 2012-08-02 | | 公開日 | 2013-02-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the N-terminal domain of human thioredoxin-interacting protein.
Acta Crystallogr.,Sect.D, 69, 2013
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1S3R
 | | Crystal structure of the human-specific toxin intermedilysin | | 分子名称: | SULFATE ION, intermedilysin | | 著者 | Polekhina, G, Giddings, K.S, Tweten, R.K, Parker, M.W. | | 登録日 | 2004-01-14 | | 公開日 | 2005-01-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2HGS
 | | HUMAN GLUTATHIONE SYNTHETASE | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLUTATHIONE, MAGNESIUM ION, ... | | 著者 | Polekhina, G, Board, P, Rossjohn, J, Parker, M.W. | | 登録日 | 1999-01-04 | | 公開日 | 1999-06-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular basis of glutathione synthetase deficiency and a rare gene permutation event.
EMBO J., 18, 1999
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1FW1
 | | Glutathione transferase zeta/maleylacetoacetate isomerase | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLUTATHIONE, GLUTATHIONE TRANSFERASE ZETA, ... | | 著者 | Polekhina, G, Board, P.G, Blackburn, A.C, Parker, M.W. | | 登録日 | 2000-09-20 | | 公開日 | 2001-09-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity.
Biochemistry, 40, 2001
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1K2F
 | | siah, Seven In Absentia Homolog | | 分子名称: | BETA-MERCAPTOETHANOL, ZINC ION, siah-1A protein | | 著者 | Polekhina, G, House, C.M, Traficante, N, Mackay, J.P, Relaix, F, Sassoon, D.A, Parker, M.W, Bowtell, D.D.L. | | 登録日 | 2001-09-26 | | 公開日 | 2001-12-28 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling.
Nat.Struct.Biol., 9, 2002
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1TTT
 | | Phe-tRNA, elongation factoR EF-TU:GDPNP ternary complex | | 分子名称: | MAGNESIUM ION, OF ELONGATION FACTOR TU (EF-TU), PHENYLALANINE, ... | | 著者 | Nissen, P, Kjeldgaard, M, Thirup, S, Polekhina, G, Reshetnikova, L, Clark, B.F.C, Nyborg, J. | | 登録日 | 1995-11-16 | | 公開日 | 1996-12-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog.
Science, 270, 1995
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3FFD
 | | Structure of parathyroid hormone-related protein complexed to a neutralizing monoclonal antibody | | 分子名称: | Monoclonal antibody, heavy chain, Fab fragment, ... | | 著者 | Mckinstry, W.J, Polekhina, G, Diefenbach-Jagger, H, Ho, P.W.M, Sato, K, Onuma, E, Gillespie, M.T, Martin, T.J, Parker, M.W. | | 登録日 | 2008-12-03 | | 公開日 | 2009-04-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for antibody discrimination between two hormones that recognize the parathyroid hormone receptor
J.Biol.Chem., 284, 2009
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2PMT
 | | GLUTATHIONE TRANSFERASE FROM PROTEUS MIRABILIS | | 分子名称: | GLUTATHIONE, GLUTATHIONE TRANSFERASE | | 著者 | Rossjohn, J, Polekhina, G, Feil, S.C, Allocati, N, Masulli, M, Diilio, C, Parker, M.W. | | 登録日 | 1998-04-28 | | 公開日 | 1999-04-27 | | 最終更新日 | 2012-01-18 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A mixed disulfide bond in bacterial glutathione transferase: functional and evolutionary implications.
Structure, 6, 1998
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2AN6
 | | Protein-peptide complex | | 分子名称: | Ubiquitin ligase SIAH1A, ZINC ION, peptide from Phyllopod | | 著者 | House, C.M, Hancock, N.C, Moller, A, Cromer, B.A, Fedorov, V, Bowtell, D.D.L, Parker, M.W, Polekhina, G. | | 登録日 | 2005-08-11 | | 公開日 | 2006-05-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Elucidation of the substrate binding site of Siah ubiquitin ligase
Structure, 14, 2006
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1PX6
 | | A folding mutant of human class pi glutathione transferase, created by mutating aspartate 153 of the wild-type protein to asparagine | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase P | | 著者 | Kong, G.K.-W, Polekhina, G, McKinstry, W.J, Parker, M.W, Dragani, B, Aceto, A, Paludi, D, Principe, D.R, Mannervik, B, Stenberg, G. | | 登録日 | 2003-07-02 | | 公開日 | 2003-07-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The multi-functional role of a highly conserved aspartic acid residue in glutathione transferase P1-1
To be Published
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1PX7
 | | A folding mutant of human class pi glutathione transferase, created by mutating aspartate 153 of the wild-type protein to glutamate | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLUTATHIONE, ... | | 著者 | Kong, G.K.-W, Polekhina, G, McKinstry, W.J, Parker, M.W, Dragani, B, Aceto, A, Paludi, D, Principe, D.R, Mannervik, B, Stenberg, G. | | 登録日 | 2003-07-02 | | 公開日 | 2003-07-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | The multi-functional role of a highly conserved aspartic acid residue in glutathione transferase P1-1
To be Published
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1LBK
 | | Crystal structure of a recombinant glutathione transferase, created by replacing the last seven residues of each subunit of the human class pi isoenzyme with the additional C-terminal helix of human class alpha isoenzyme | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase class pi chimaera (CODA), ... | | 著者 | Kong, G.K.W, Micaloni, C, Mazzetti, A.P, Nuccetelli, M, Antonini, G, Stella, L, McKinstry, W.J, Polekhina, G, Rossjohn, J, Federici, G, Ricci, G, Parker, M.W, Lo Bello, M. | | 登録日 | 2002-04-04 | | 公開日 | 2002-04-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences.
J.Mol.Biol., 325, 2003
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1MD4
 | | A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to valine | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase | | 著者 | Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W. | | 登録日 | 2002-08-06 | | 公開日 | 2002-08-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1
J.Biol.Chem., 278, 2003
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1MD3
 | | A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to alanine | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase | | 著者 | Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W. | | 登録日 | 2002-08-06 | | 公開日 | 2002-08-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1
J.Biol.Chem., 278, 2003
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1PMT
 | | GLUTATHIONE TRANSFERASE FROM PROTEUS MIRABILIS | | 分子名称: | GLUTATHIONE, GLUTATHIONE TRANSFERASE | | 著者 | Rossjohn, J, Polekhina, G, Feil, S.C, Allocati, N, Masulli, M, Diilio, C, Parker, M.W. | | 登録日 | 1998-03-23 | | 公開日 | 1999-04-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A mixed disulfide bond in bacterial glutathione transferase: functional and evolutionary implications.
Structure, 6, 1998
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1M3J
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1M3I
 | | Perfringolysin O, new crystal form | | 分子名称: | perfringolysin O | | 著者 | Rossjohn, J, Parker, M, Polekhina, G, Feil, S, Tweten, R. | | 登録日 | 2002-06-28 | | 公開日 | 2004-02-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Snapshots in the Molecular Mechanism of PFO Revealed
To be Published
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2FHE
 | | FASCIOLA HEPATICA GLUTATHIONE S-TRANSFERASE ISOFORM 1 IN COMPLEX WITH GLUTATHIONE | | 分子名称: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE | | 著者 | Polekhina, G, Rossjohn, J, Feil, S.C, Parker, M.W. | | 登録日 | 1998-10-21 | | 公開日 | 1998-10-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase.
J.Mol.Biol., 273, 1997
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1EFC
 | | INTACT ELONGATION FACTOR FROM E.COLI | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (ELONGATION FACTOR) | | 著者 | Song, H, Parsons, M.R, Rowsell, S, Leonard, G, Phillips, S.E.V. | | 登録日 | 1998-11-24 | | 公開日 | 1999-03-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of intact elongation factor EF-Tu from Escherichia coli in GDP conformation at 2.05 A resolution.
J.Mol.Biol., 285, 1999
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1B23
 | | E. coli cysteinyl-tRNA and T. aquaticus elongation factor EF-TU:GTP ternary complex | | 分子名称: | CYSTEINE, CYSTEINYL TRNA, ELONGATION FACTOR TU, ... | | 著者 | Nissen, P, Kjeldgaard, M, Thirup, S, Nyborg, J. | | 登録日 | 1998-12-04 | | 公開日 | 1998-12-07 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA.
Structure Fold.Des., 7, 1999
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1LU3
 | | Separate Fitting of the Anticodon Loop Region of tRNA (nucleotide 26-42) in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome | | 分子名称: | PHENYLALANINE TRANSFER RNA | | 著者 | Valle, M, Sengupta, J, Swami, N.K, Grassucci, R.A, Burkhardt, N, Nierhaus, K.H, Agrawal, R.K, Frank, J. | | 登録日 | 2002-05-21 | | 公開日 | 2002-06-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (16.799999 Å) | | 主引用文献 | Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
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