4KZE
 
 | | Crystal structure of an RNA aptamer in complex with Fab | | 分子名称: | BL3-6 Fab antibody, heavy chain, light chain, ... | | 著者 | Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | | 登録日 | 2013-05-29 | | 公開日 | 2014-06-18 | | 最終更新日 | 2014-07-30 | | 実験手法 | X-RAY DIFFRACTION (2.404 Å) | | 主引用文献 | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
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6MWN
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2KFZ
 | | KLENOW FRAGMENT WITH BRIDGING-SULFUR SUBSTRATE AND ZINC ONLY | | 分子名称: | 5'-D(*GP*CP*TP*TP*AP*(US1)P*G)-3', KLENOW FRAGMENT OF DNA POLYMERASE I, MAGNESIUM ION, ... | | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | | 登録日 | 1998-07-02 | | 公開日 | 1998-11-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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2KFN
 | | KLENOW FRAGMENT WITH BRIDGING-SULFUR SUBSTRATE AND MANGANESE | | 分子名称: | 5'-D(*GP*CP*TP*TP*AP*(US1)P*G)-3', KLENOW FRAGMENT OF DNA POLYMERASE I, MAGNESIUM ION, ... | | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | | 登録日 | 1998-07-01 | | 公開日 | 1998-11-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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2KZZ
 | | KLENOW FRAGMENT WITH NORMAL SUBSTRATE AND ZINC ONLY | | 分子名称: | DNA (5'-D(*GP*CP*TP*T*AP*CP*G)-3'), PROTEIN (DNA POLYMERASE I), ZINC ION | | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | | 登録日 | 1998-07-07 | | 公開日 | 1999-12-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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2KZM
 | | KLENOW FRAGMENT WITH NORMAL SUBSTRATE AND ZINC AND MANGANESE | | 分子名称: | DNA (5'-D(*GP*CP*TP*TP*A*CP*GP*C)-3'), MANGANESE (II) ION, PROTEIN (DNA POLYMERASE I), ... | | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | | 登録日 | 1998-07-03 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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5C7W
 | | 5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine. | | 分子名称: | 5'-monophosphate Z:P guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE | | 著者 | Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A. | | 登録日 | 2015-06-25 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.
Angew.Chem.Int.Ed.Engl., 54, 2015
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5C7U
 | | 5'-monophosphate wt Guanine Riboswitch bound to hypoxanthine. | | 分子名称: | 5'-monophosphate wt guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE | | 著者 | Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A. | | 登録日 | 2015-06-24 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.
Angew.Chem.Int.Ed.Engl., 54, 2015
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5E08
 | | Specific Recognition of a Single-stranded RNA Sequence by an Engineered Synthetic Antibody Fragment | | 分子名称: | Fab Heavy Chain, Fab Light Chain, RNA | | 著者 | Huang, H, Qin, D, Li, N, Shao, Y, Staley, J.P, Kossiakoff, A.A, Koide, S, Piccirilli, J.A. | | 登録日 | 2015-09-28 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
J.Mol.Biol., 428, 2016
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4Q9Q
 | | Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab | | 分子名称: | (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | | 著者 | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | | 登録日 | 2014-05-01 | | 公開日 | 2014-06-18 | | 最終更新日 | 2017-07-26 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
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4Q9R
 | | Crystal structure of an RNA aptamer bound to trifluoroethyl-ligand analog in complex with Fab | | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | | 著者 | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | | 登録日 | 2014-05-01 | | 公開日 | 2014-06-18 | | 最終更新日 | 2017-07-26 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
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6R47
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7MLX
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3HHN
 | | Crystal structure of class I ligase ribozyme self-ligation product, in complex with U1A RBD | | 分子名称: | Class I ligase ribozyme, self-ligation product, MAGNESIUM ION, ... | | 著者 | Shechner, D.M, Grant, R.A, Bagby, S.C, Bartel, D.P. | | 登録日 | 2009-05-15 | | 公開日 | 2009-11-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.987 Å) | | 主引用文献 | Crystal structure of the catalytic core of an RNA-polymerase ribozyme.
Science, 326, 2009
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3QHT
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6MIH
 | | Crystal structure of host-guest complex with PC hachimoji DNA | | 分子名称: | DNA (5'-D(*CP*TP*TP*AP*(1WA)P*CP*(DB)P*T)-3'), DNA (5'-D(P*AP*(DS)P*GP*(1W5)P*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase | | 著者 | Georgiadis, M.M. | | 登録日 | 2018-09-19 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
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6MIG
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6MIK
 | | Crystal structure of host-guest complex with PP hachimoji DNA | | 分子名称: | DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase | | 著者 | Georgiadis, M.M. | | 登録日 | 2018-09-19 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
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7R6N
 | | Exon-free state of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic trimeric construct | | 分子名称: | Group I intron, MAGNESIUM ION | | 著者 | Thelot, F, Liu, D, Liao, M, Yin, P. | | 登録日 | 2021-06-22 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly.
Nat.Methods, 19, 2022
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7R6M
 | | Post-2S intermediate of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic dimeric construct | | 分子名称: | Group I intron, Ligated exon mimic of the Group I intron, MAGNESIUM ION | | 著者 | Thelot, F, Liu, D, Liao, M, Yin, P. | | 登録日 | 2021-06-22 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly.
Nat.Methods, 19, 2022
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7R6L
 | | 5 prime exon-free pre-2S intermediate of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic dimeric construct | | 分子名称: | Group I intron, 3 prime fragment plus 3 prime exon, 5 prime fragment, ... | | 著者 | Thelot, F, Liu, D, Liao, M, Yin, P. | | 登録日 | 2021-06-22 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly.
Nat.Methods, 19, 2022
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4ONO
 | | CD1c in complex with PM (phosphomycoketide) | | 分子名称: | (4R,8S,16S,20R)-4,8,12,16,20-pentamethylheptacosyl dihydrogen phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin/T-cell surface glycoprotein CD1c/T-cell surface glycoprotein CD1b chimeric protein, ... | | 著者 | Roy, S, Adams, E.J. | | 登録日 | 2014-01-28 | | 公開日 | 2014-10-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.705 Å) | | 主引用文献 | Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by alpha beta T cells.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4ONH
 | | Crystal Structure of DN6 TCR | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | | 著者 | Roy, S, Adams, E.J. | | 登録日 | 2014-01-28 | | 公開日 | 2014-10-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.008 Å) | | 主引用文献 | Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by alpha beta T cells.
Proc.Natl.Acad.Sci.USA, 111, 2014
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