6DLR
 
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6DMD
 | | ppGpp Riboswitch bound to ppGpp, manganese chloride structure | | 分子名称: | GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, MANGANESE (II) ION, ... | | 著者 | Peselis, A, Serganov, A. | | 登録日 | 2018-06-05 | | 公開日 | 2018-11-14 | | 最終更新日 | 2022-04-27 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands.
Nat. Chem. Biol., 14, 2018
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6DNR
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6DLQ
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6DLT
 | | PRPP Riboswitch bound to PRPP, native structure | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, PRPP Riboswitch, ... | | 著者 | Peselis, A, Serganov, A. | | 登録日 | 2018-06-02 | | 公開日 | 2018-11-14 | | 最終更新日 | 2022-04-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands.
Nat. Chem. Biol., 14, 2018
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6DLS
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6DMC
 | | ppGpp Riboswitch bound to ppGpp, native structure | | 分子名称: | GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... | | 著者 | Peselis, A, Serganov, A. | | 登録日 | 2018-06-04 | | 公開日 | 2018-11-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands.
Nat. Chem. Biol., 14, 2018
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6DME
 | | ppGpp Riboswitch bound to ppGpp, thallium acetate structure | | 分子名称: | GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, THALLIUM (I) ION, ... | | 著者 | Peselis, A, Serganov, A. | | 登録日 | 2018-06-05 | | 公開日 | 2018-11-14 | | 最終更新日 | 2022-04-27 | | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | | 主引用文献 | ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands.
Nat. Chem. Biol., 14, 2018
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4GXY
 | | RNA structure | | 分子名称: | Adenosylcobalamin, Adenosylcobalamin riboswitch, IRIDIUM HEXAMMINE ION, ... | | 著者 | Serganov, A, Peselis, A. | | 登録日 | 2012-09-04 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural insights into ligand binding and gene expression control by an adenosylcobalamin riboswitch.
Nat.Struct.Mol.Biol., 19, 2012
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5DDQ
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5DDR
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5DDP
 | | L-glutamine riboswitch bound with L-glutamine | | 分子名称: | GLUTAMINE, MAGNESIUM ION, RNA (61-MER), ... | | 著者 | Ren, A, Patel, D.J. | | 登録日 | 2015-08-25 | | 公開日 | 2015-12-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | | 主引用文献 | Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
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5DDO
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7MD9
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7MD1
 | | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-02 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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7MCQ
 | | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, AOAA-bound enzyme in dimeric form | | 分子名称: | 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-02 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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7MCB
 | | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase Holoenzyme | | 分子名称: | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-01 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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7MCP
 | | Crystal structure of Staphylococcus aureus Cystathionine gamma-lyase, Holoenzyme dimer | | 分子名称: | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-02 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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7MD6
 | | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103N mutant co-crystallized with NL1 | | 分子名称: | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, CITRATE ANION, N-[(6-bromo-1H-indol-1-yl)acetyl]glycine, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-03 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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7MDB
 | | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme Y103A mutant co-crystallized with NL2 | | 分子名称: | 5-[(6-bromo-1H-indol-1-yl)methyl]-2-methylfuran-3-carboxylic acid, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, CACODYLATE ION, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-03 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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7MCN
 | | Crystal structure of Staphylococcus aureus Cystathionine gamma-lyase, Holoenzyme with High HEPES | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-02 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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7MCT
 | | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, Holoenzyme with bound NL1 | | 分子名称: | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, N-[(6-bromo-1H-indol-1-yl)acetyl]glycine, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-02 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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7MD0
 | | Crystal structure of Staphylococcus aureus cystathionine gamma lyase holoenzyme in the presence of NL1F3 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-02 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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7MCL
 | | Crystal structure of Staphylococcus aureus Cystathionine gamma-lyase, PLP bound | | 分子名称: | Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-02 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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7MCY
 | | Crystal structure of Staphylococcus aureus Cystathionine gamma lyase, Holoenzyme with bound NL3 | | 分子名称: | 3-{[6-(7-chloro-1-benzothiophen-2-yl)-1H-indol-1-yl]methyl}-1H-pyrazole-5-carboxylic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase, ... | | 著者 | Nuthanakanti, A, Serganov, A, Kaushik, A. | | 登録日 | 2021-04-02 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Inhibitors of bacterial H 2 S biogenesis targeting antibiotic resistance and tolerance.
Science, 372, 2021
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