1COL
| REFINED STRUCTURE OF THE PORE-FORMING DOMAIN OF COLICIN A AT 2.4 ANGSTROMS RESOLUTION | 分子名称: | COLICIN A | 著者 | Parker, M.W, Postma, J.P.M, Pattus, F, Tucker, A.D, Tsernoglou, D. | 登録日 | 1991-07-06 | 公開日 | 1992-07-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Refined structure of the pore-forming domain of colicin A at 2.4 A resolution. J.Mol.Biol., 224, 1992
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4QDQ
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4QDR
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4QDS
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1PRE
| PROAEROLYSIN | 分子名称: | PROAEROLYSIN | 著者 | Parker, M.W, Buckley, J.T, Postma, J.P.M, Tucker, A.D, Tsernoglou, D. | 登録日 | 1995-09-15 | 公開日 | 1996-10-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states. Nature, 367, 1994
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1Z52
| Proaerolysin Mutant W373L | 分子名称: | Aerolysin | 著者 | Parker, M.W, Feil, S.C, Tang, J.W. | 登録日 | 2005-03-16 | 公開日 | 2006-03-07 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Crystal Structure of Proaerolysin at 2.3 A Resolution and Structural Analyses of Single-site Mutants as a Basis for Understanding Membrane Insertion of the Toxin To be Published
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5DIM
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5DHL
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4NKQ
| Structure of a Cytokine Receptor Complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit beta, Granulocyte-macrophage colony-stimulating factor, ... | 著者 | Parker, M.W, Broughton, S.E. | 登録日 | 2013-11-13 | 公開日 | 2015-09-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.301 Å) | 主引用文献 | Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling. Structure, 24, 2016
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4ZGH
| Structure of Sugar Binding Protein Pneumolysin | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GOLD (I) CYANIDE ION, ... | 著者 | Parker, M.W, Feil, S.C, Morton, C. | 登録日 | 2015-04-23 | 公開日 | 2016-03-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation. Sci Rep, 5, 2015
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6XD4
| CDC-like protein | 分子名称: | ACETATE ION, Hemolysin, SODIUM ION | 著者 | Morton, C.J, Parker, M.W, Lawrence, S.L, Johnstone, B.A, Tweten, R.K. | 登録日 | 2020-06-09 | 公開日 | 2021-04-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins. Mbio, 11, 2020
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19GS
| Glutathione s-transferase p1-1 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,3'-(4,5,6,7-TETRABROMO-3-OXO-1(3H)-ISOBENZOFURANYLIDENE)BIS [6-HYDROXYBENZENESULFONIC ACID]ANION, GLUTATHIONE, ... | 著者 | Oakley, A.J, Lo Bello, M, Parker, M.W. | 登録日 | 1997-12-14 | 公開日 | 1998-12-30 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site). J.Mol.Biol., 291, 1999
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1A87
| COLICIN N | 分子名称: | COLICIN N | 著者 | Vetter, I.R, Parker, M.W, Tucker, A.D, Lakey, J.H, Pattus, F, Tsernoglou, D. | 登録日 | 1998-04-03 | 公開日 | 1999-04-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structure of a colicin N fragment suggests a model for toxicity. Structure, 6, 1998
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8E3W
| BRD4-D1 in complex with BET inhibitor | 分子名称: | (4P)-4-[2-(cyclopropylmethoxy)-5-(methanesulfonyl)phenyl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | 著者 | Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W. | 登録日 | 2022-08-17 | 公開日 | 2023-03-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography. Chem.Commun.(Camb.), 59, 2023
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8E17
| BRD4-D1 in complex with BET inhibitor | 分子名称: | (4P,6M)-6-[1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl]-4-[5-(methanesulfonyl)-2-methoxyphenyl]-2-methylisoquinolin-1(2H)-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | 著者 | Gorman, M.A, Fitzgerald, C.G.D, White, J.M, Parker, M.W. | 登録日 | 2022-08-09 | 公開日 | 2023-03-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography. Chem.Commun.(Camb.), 59, 2023
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8G32
| Pro-form of a CDCL short from E. anophelis | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... | 著者 | Johnstone, B.A, Christie, M.P, Morton, C.J, Parker, M.W. | 登録日 | 2023-02-06 | 公開日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Pro-form of a CDCL short from E. anophelis To Be Published
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8G33
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1ZGN
| Crystal Structure of the Glutathione Transferase Pi in Complex with Dinitrosyl-diglutathionyl Iron Complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FE (III) ION, GLUTATHIONE, ... | 著者 | Parker, L.J, Adams, J.J, Parker, M.W. | 登録日 | 2005-04-21 | 公開日 | 2005-11-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo J.Biol.Chem., 280, 2005
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12GS
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13GS
| GLUTATHIONE S-TRANSFERASE COMPLEXED WITH SULFASALAZINE | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID, GLUTATHIONE, ... | 著者 | Oakley, A.J, Lo Bello, M, Parker, M.W. | 登録日 | 1997-11-20 | 公開日 | 1999-01-13 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Ligandin (Non-Substrate) Binding Site of Human Pi Class Glutathione Transferase is Located in the Electrophile Binding Site (H-Site). J.Mol.Biol., 291, 1999
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14GS
| GLUTATHIONE S-TRANSFERASE P1-1 APO FORM 1 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE | 著者 | Oakley, A.J, Lo Bello, M, Ricci, G, Federici, G, Parker, M.W. | 登録日 | 1997-11-29 | 公開日 | 1999-01-13 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Evidence for an induced-fit mechanism operating in pi class glutathione transferases. Biochemistry, 37, 1998
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17GS
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18GS
| GLUTATHIONE S-TRANSFERASE P1-1 COMPLEXED WITH 1-(S-GLUTATHIONYL)-2,4-DINITROBENZENE | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE | 著者 | Oakley, A.J, Lo Bello, M, Ricci, G, Federici, G, Parker, M.W. | 登録日 | 1997-12-07 | 公開日 | 1999-01-13 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site). J.Mol.Biol., 291, 1999
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11GS
| Glutathione s-transferase complexed with ethacrynic acid-glutathione conjugate (form ii) | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ETHACRYNIC ACID, GLUTATHIONE, ... | 著者 | Oakley, A.J, Lo Bello, M, Mazzetti, A.P, Federici, G, Parker, M.W. | 登録日 | 1997-11-03 | 公開日 | 1999-01-13 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The glutathione conjugate of ethacrynic acid can bind to human pi class glutathione transferase P1-1 in two different modes. FEBS Lett., 419, 1997
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16GS
| GLUTATHIONE S-TRANSFERASE P1-1 APO FORM 3 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE, SULFATE ION | 著者 | Oakley, A.J, Lo Bello, M, Ricci, G, Federici, G, Parker, M.W. | 登録日 | 1997-11-30 | 公開日 | 1999-01-13 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Evidence for an induced-fit mechanism operating in pi class glutathione transferases. Biochemistry, 37, 1998
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