11GS

Glutathione s-transferase complexed with ethacrynic acid-glutathione conjugate (form ii)

Summary for 11GS

DescriptorGLUTATHIONE S-TRANSFERASE, GLUTATHIONE, ETHACRYNIC ACID, ... (5 entities in total)
Functional Keywordstransferase, ethacrynic acid
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight48366.94
Authors
Oakley, A.J.,Lo Bello, M.,Mazzetti, A.P.,Federici, G.,Parker, M.W. (deposition date: 1997-11-03, release date: 1999-01-13, Last modification date: 2011-07-13)
Primary citation
Oakley, A.J.,Lo Bello, M.,Mazzetti, A.P.,Federici, G.,Parker, M.W.
The glutathione conjugate of ethacrynic acid can bind to human pi class glutathione transferase P1-1 in two different modes.
FEBS Lett., 419:32-36, 1997
PubMed: 9426214 (PDB entries with the same primary citation)
DOI: 10.1016/S0014-5793(97)01424-5
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26190.5%5.7%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report