7UI1
| Pfs230 D1D2 domain in complex with 230AL-37 | Descriptor: | 230AL-37, Gametocyte surface protein P230, SULFATE ION | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-28 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7UC8
| Pfs230 D1 domain in complex with 230AS-73 | Descriptor: | 230AS-73, Gametocyte surface protein P230, SODIUM ION | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-16 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7UBS
| Pfs230 D1 domain in complex with 230AS-26 | Descriptor: | 230AS-26, Gametocyte surface protein P230 | Authors: | Tang, W.K, Tolia, N.H. | Deposit date: | 2022-03-15 | Release date: | 2023-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine. Immunity, 56, 2023
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7UNB
| Crystal structure of malaria transmission-blocking antigen Pfs48/45-6C variant in complex with human antibodies RUPA-117 and RUPA-47 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gametocyte surface protein P45/48, RUPA-117 Fab heavy chain, ... | Authors: | Hailemariam, S, McLeod, B, Julien, J.-P. | Deposit date: | 2022-04-10 | Release date: | 2022-08-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses. Immunity, 55, 2022
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6AZZ
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1190 | Descriptor: | 1190 antibody, heavy chain, light chain, ... | Authors: | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | Deposit date: | 2017-09-13 | Release date: | 2017-11-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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6B0E
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260 | Descriptor: | 1260 antibody, heavy chain, light chain, ... | Authors: | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | Deposit date: | 2017-09-14 | Release date: | 2017-11-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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6B0G
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245 | Descriptor: | 1245 Antibody, Heavy Chain, Light Chain, ... | Authors: | McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P. | Deposit date: | 2017-09-14 | Release date: | 2017-11-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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6B0A
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1269 | Descriptor: | 1269 antibody, heavy chain, light chain, ... | Authors: | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | Deposit date: | 2017-09-14 | Release date: | 2017-11-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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6B08
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1276 | Descriptor: | 1276 antibody, heavy chain, light chain, ... | Authors: | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | Deposit date: | 2017-09-14 | Release date: | 2017-11-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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6B0H
| Crystal structure of Pfs25 in complex with the transmission blocking antibody 1262 | Descriptor: | 1,2-ETHANEDIOL, 1262 antibody, heavy chain, ... | Authors: | McLeod, B, Scally, S.W, Bosch, A, King, C.R, Julien, J.P. | Deposit date: | 2017-09-14 | Release date: | 2017-11-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nat Commun, 8, 2017
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3SSI
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7ZXF
| Pfs48/45 bound to monoclonal antibodies 10D8 and 85RF45.1 | Descriptor: | 10D8 heavy chain, 10D8 light chain, 85RF45.1 heavy chain, ... | Authors: | Ko, K.T, Lennartz, F.L, Higgins, M.K. | Deposit date: | 2022-05-20 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.72 Å) | Cite: | Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies. Nat Commun, 13, 2022
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7ZWF
| Pfs48/45 bound to scFv fragment of monoclonal antibody 32F3 | Descriptor: | 32F3scFv, Gametocyte surface protein P45/48, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Ko, K.T, Lennartz, F.L, Higgins, M.K. | Deposit date: | 2022-05-19 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.132 Å) | Cite: | Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies. Nat Commun, 13, 2022
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7ZXG
| Pfs48/45 bound to Fab fragment of monoclonal antibody 10D8 | Descriptor: | 10D8 heavy chain, 10D8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ko, K.T, Lennartz, F.L, Higgins, M.K. | Deposit date: | 2022-05-20 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies. Nat Commun, 13, 2022
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7ZWM
| Pfs48/45 central and C-terminal domains bound to Fab fragments of monoclonal antibody 10D8 and 32F3 | Descriptor: | 10D8 heavy chain, 10D8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ko, K.T, Lennartz, F.L, Higgins, M.K. | Deposit date: | 2022-05-19 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.69 Å) | Cite: | Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies. Nat Commun, 13, 2022
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7ZWI
| Pfs48/45 C-terminal domain bound to fab fragment of monoclonal antibody 32F3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 32F3 heavy chain, 32F3 light chain, ... | Authors: | Ko, K.T, Lennartz, F.L, Higgins, M.K. | Deposit date: | 2022-05-19 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies. Nat Commun, 13, 2022
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3SIC
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1Q21
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6Q21
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2Q21
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