8HNM
 
 | | CXCR3-DNGi complex activated by VUF11222 | | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Jiao, H.Z, Hu, H.L. | | Deposit date: | 2022-12-08 | | Release date: | 2023-11-29 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structural insights into the activation and inhibition of CXC chemokine receptor 3.
Nat.Struct.Mol.Biol., 31, 2024
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8HNN
 | | Structure of CXCR3 complexed with antagonist SCH546738 | | Descriptor: | 3-azanyl-6-chloranyl-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethyl-piperazin-1-yl]pyrazine-2-carboxamide, CHOLESTEROL, Nb6, ... | | Authors: | Jiao, H.Z, Hu, H.L. | | Deposit date: | 2022-12-08 | | Release date: | 2023-11-29 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural insights into the activation and inhibition of CXC chemokine receptor 3.
Nat.Struct.Mol.Biol., 31, 2024
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8HNK
 | | CXCR3-DNGi complex activated by CXCL11 | | Descriptor: | C-X-C motif chemokine 11, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Jiao, H.Z, Hu, H.L. | | Deposit date: | 2022-12-08 | | Release date: | 2023-11-29 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structural insights into the activation and inhibition of CXC chemokine receptor 3.
Nat.Struct.Mol.Biol., 31, 2024
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8HNL
 | | CXCR3-DNGi complex activated by PS372424 | | Descriptor: | (3S)-N-[(2S)-5-carbamimidamido-1-(cyclohexylmethylamino)-1-oxidanylidene-pentan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1H-isoquinoline-3-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Jiao, H.Z, Hu, H.L. | | Deposit date: | 2022-12-08 | | Release date: | 2023-11-29 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Structural insights into the activation and inhibition of CXC chemokine receptor 3.
Nat.Struct.Mol.Biol., 31, 2024
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3PLY
 | | Structure of Oxidized P96G Mutant of Amicyanin | | Descriptor: | Amicyanin, COPPER (II) ION, PHOSPHATE ION, ... | | Authors: | Sukumar, N, Davidson, V.L. | | Deposit date: | 2010-11-15 | | Release date: | 2011-02-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Proline 96 of the copper ligand loop of amicyanin regulates electron transfer from methylamine dehydrogenase by positioning other residues at the protein-protein interface.
Biochemistry, 50, 2011
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3RLM
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8K9F
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8K9E
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3RMZ
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3RN0
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3SJL
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3SLE
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3SVW
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4OJK
 | | Structure of the cGMP Dependent Protein Kinase II and Rab11b Complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-11B, cGMP-dependent protein kinase 2 | | Authors: | Reger, A.S, Yang, M.P, Guo, E, Kim, C. | | Deposit date: | 2014-01-21 | | Release date: | 2014-08-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.657 Å) | | Cite: | Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions.
J.Biol.Chem., 289, 2014
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2KX4
 | | Solution structure of Bacteriophage Lambda gpFII | | Descriptor: | Tail attachment protein | | Authors: | Maxwell, K.L, Cardarelli, L, Neudecker, P, Davidson, A.R, Ontario Centre for Structural Proteomics (OCSP) | | Deposit date: | 2010-04-26 | | Release date: | 2010-07-28 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Phages have adapted the same protein fold to fulfill multiple functions in virion assembly.
Proc.Natl.Acad.Sci.USA, 107, 2010
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6B2Q
 | | Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis | | Descriptor: | 3-methyl-1-(2-methylpropyl)butyl 4-O-beta-L-gulopyranosyl-beta-D-glucopyranoside, 5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknA | | Authors: | Zuccola, H.J. | | Deposit date: | 2017-09-20 | | Release date: | 2018-02-14 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.
ACS Med Chem Lett, 8, 2017
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6B2P
 | | Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis | | Descriptor: | 5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknB | | Authors: | Zuccola, H.J. | | Deposit date: | 2017-09-20 | | Release date: | 2018-02-14 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.
ACS Med Chem Lett, 8, 2017
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7FJJ
 | | human Pol III pre-termination complex | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Hou, H, Xu, Y. | | Deposit date: | 2021-08-04 | | Release date: | 2021-10-27 | | Last modified: | 2021-11-10 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.
Nat Commun, 12, 2021
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7FJI
 | | human Pol III elongation complex | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Hou, H, Xu, Y. | | Deposit date: | 2021-08-04 | | Release date: | 2021-10-27 | | Last modified: | 2021-11-10 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.
Nat Commun, 12, 2021
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7FEB
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7FED
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7FEC
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7JIF
 | | HRAS A59T GppNHp | | Descriptor: | GLYCEROL, GTPase HRas, MAGNESIUM ION, ... | | Authors: | Johnson, C.W, Haigis, K.M. | | Deposit date: | 2020-07-23 | | Release date: | 2022-03-02 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.757 Å) | | Cite: | Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
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7JII
 | | HRAS A59E GDP | | Descriptor: | CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Johnson, C.W, Haigis, K.M. | | Deposit date: | 2020-07-23 | | Release date: | 2022-03-02 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.532 Å) | | Cite: | Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
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7JIG
 | | HRAS A59T GppNHp crystal 2 | | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | | Authors: | Johnson, C.W, Haigis, K.M. | | Deposit date: | 2020-07-23 | | Release date: | 2022-03-02 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.322 Å) | | Cite: | Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
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