1MRQ
 
 | | Crystal structure of human 20alpha-HSD in ternary complex with NADP and 20alpha-hydroxy-progesterone | | 分子名称: | Aldo-keto reductase family 1 member C1, BETA-MERCAPTOETHANOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Couture, J.F, Legrand, P, Cantin, L, Luu-The, V, Labrie, F, Breton, R. | | 登録日 | 2002-09-18 | | 公開日 | 2003-09-30 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids.
J.Mol.Biol., 331, 2003
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2YOE
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with GABA and flurazepam | | 分子名称: | CYS-LOOP LIGAND-GATED ION CHANNEL, Flurazepam, GAMMA-AMINO-BUTANOIC ACID | | 著者 | Spurny, R, Brams, M, Nury, H, Legrand, P, Ulens, C. | | 登録日 | 2012-10-23 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Pentameric Ligand-Gated Ion Channel Elic is Activated by Gaba and Modulated by Benzodiazepines.
Proc.Natl.Acad.Sci.USA, 109, 2012
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6R5M
 | | Crystal structure of toxin MT9 from mamba venom | | 分子名称: | ACETYL GROUP, Dendroaspis polylepis MT9, GLYCEROL, ... | | 著者 | Stura, E.A, Tepshi, L, Ciolek, J, Triquigneaux, M, Zoukimian, C, De Waard, M, Beroud, R, Servent, D, Gilles, N, Legrand, P, Ciccone, L. | | 登録日 | 2019-03-25 | | 公開日 | 2020-02-12 | | 最終更新日 | 2022-05-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries
Biomed Pharmacother, 150, 2022
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1Q13
 | | Crystal structure of rabbit 20alpha hyroxysteroid dehydrogenase in ternary complex with NADP and testosterone | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin-E2 9-reductase, SULFATE ION, ... | | 著者 | Couture, J.-F, Cantin, L, Legrand, P, Luu-The, V, Labrie, F, Breton, R. | | 登録日 | 2003-07-18 | | 公開日 | 2004-11-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Loop relaxation, a mechanism that explains the reduced specificity of rabbit 20alpha-hydroxysteroid dehydrogenase, a member of the aldo-keto reductase superfamily.
J. Mol. Biol., 339, 2004
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1Q5M
 | | Binary complex of rabbit 20alpha-hydroxysteroid dehydrogenase with NADPH | | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin-E2 9-reductase, SULFATE ION | | 著者 | Couture, J.F, Legrand, P, Cantin, L, Labrie, F, Luu-The, V, Breton, R. | | 登録日 | 2003-08-08 | | 公開日 | 2004-05-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Loop Relaxation, A Mechanism that Explains the Reduced Specificity of Rabbit 20alpha-Hydroxysteroid Dehydrogenase, A Member of the Aldo-Keto Reductase Superfamily.
J.Mol.Biol., 339, 2004
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5OLL
 | | Crystal structure of gurmarin, a sweet taste suppressing polypeptide | | 分子名称: | Gurmarin, NICKEL (II) ION | | 著者 | Sigoillot, M, Neiers, F, Legrand, P, Roblin, P, Briand, L. | | 登録日 | 2017-07-28 | | 公開日 | 2018-08-08 | | 最終更新日 | 2019-02-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The Crystal Structure of Gurmarin, a Sweet Taste-Suppressing Protein: Identification of the Amino Acid Residues Essential for Inhibition.
Chem. Senses, 43, 2018
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6ERG
 | | Complex of XLF and heterodimer Ku bound to DNA | | 分子名称: | DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ... | | 著者 | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | | 登録日 | 2017-10-18 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
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6ERH
 | | Complex of XLF and heterodimer Ku bound to DNA | | 分子名称: | DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ... | | 著者 | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | | 登録日 | 2017-10-18 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
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5AMS
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6ERF
 | | Complex of APLF factor and Ku heterodimer bound to DNA | | 分子名称: | Aprataxin and PNK-like factor, DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ... | | 著者 | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | | 登録日 | 2017-10-18 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat.Struct.Mol.Biol., 25, 2018
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6SHX
 | | DNA mismatch repair proteins MLH1 and MLH3 | | 分子名称: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | | 著者 | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | | 登録日 | 2019-08-08 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6SNS
 | | DNA mismatch repair proteins MLH1 and MLH3 | | 分子名称: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | | 著者 | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | | 登録日 | 2019-08-27 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6SNV
 | | DNA mismatch repair proteins MLH1 and MLH3 | | 分子名称: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | | 著者 | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | | 登録日 | 2019-08-27 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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2V7F
 | | Structure of P. abyssi RPS19 protein | | 分子名称: | CHLORIDE ION, RPS19E SSU RIBOSOMAL PROTEIN S19E | | 著者 | Gregory, L.A, Aguissa-Toure, A.H, Pinaud, N, Legrand, P, Gleizes, P.E, Fribourg, S. | | 登録日 | 2007-07-30 | | 公開日 | 2007-09-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Molecular Basis of Diamond Blackfan Anemia: Structure and Function Analysis of Rps19.
Nucleic Acids Res., 35, 2007
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4A98
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromoflurazepam | | 分子名称: | 7-BROMO-1-[2-(DIETHYLAMINO)ETHYL]-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE, CYS-LOOP LIGAND-GATED ION CHANNEL | | 著者 | Spurny, R, Brams, M, Nury, H, Legrand, P, Ulens, C. | | 登録日 | 2011-11-24 | | 公開日 | 2012-10-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.61 Å) | | 主引用文献 | Pentameric Ligand-Gated Ion Channel Elic is Activated by Gaba and Modulated by Benzodiazepines.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5EPV
 | | Histidine kinase domain from the LOV-HK blue-light receptor from Brucella abortus | | 分子名称: | Blue-light-activated histidine kinase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | | 著者 | Rinaldi, J, Guimaraes, B.G, Legrand, P, Thompson, A, Paris, G, Goldbaum, F.A, Klinke, S. | | 登録日 | 2015-11-12 | | 公開日 | 2016-02-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structural Insights into the HWE Histidine Kinase Family: The Brucella Blue Light-Activated Histidine Kinase Domain.
J.Mol.Biol., 428, 2016
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2XV4
 | | Structure of Human RPC62 (partial) | | 分子名称: | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3, PHOSPHATE ION | | 著者 | Lefevre, S, Legrand, P, Fribourg, S. | | 登録日 | 2010-10-22 | | 公開日 | 2011-03-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure-Function Analysis of Hrpc62 Provides Insights Into RNA Polymerase III Transcription
Nat.Struct.Mol.Biol., 18, 2011
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2XUB
 | | Human RPC62 subunit structure | | 分子名称: | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 | | 著者 | Lefevre, S, Legrand, P, Fribourg, S. | | 登録日 | 2010-10-18 | | 公開日 | 2011-03-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-Function Analysis of Hrpc62 Provides Insights Into RNA Polymerase III Transcription
Nat.Struct.Mol.Biol., 18, 2011
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4E4W
 | | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer | | 分子名称: | 1,2-ETHANEDIOL, DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, ... | | 著者 | Gueneau, E, Legrand, P, Charbonnier, J.B. | | 登録日 | 2012-03-13 | | 公開日 | 2013-02-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the MutLalpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
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4FMN
 | | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of NTG2 | | 分子名称: | 1,2-ETHANEDIOL, DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, ... | | 著者 | Gueneau, E, Legrand, P, Charbonnier, J.B. | | 登録日 | 2012-06-18 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
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4FMO
 | | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of exo1 | | 分子名称: | DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, DNA repair peptide, ... | | 著者 | Gueneau, E, Legrand, P, Charbonnier, J.B. | | 登録日 | 2012-06-18 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | | 主引用文献 | Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
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3CAO
 | | OXIDISED STRUCTURE OF THE ACIDIC CYTOCHROME C3 FROM DESULFOVIBRIO AFRICANUS | | 分子名称: | ARSENIC, CYTOCHROME C3, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Norager, S, Legrand, P, Pieulle, L, Hatchikian, C, Roth, M. | | 登録日 | 1998-11-17 | | 公開日 | 2000-07-23 | | 最終更新日 | 2018-04-11 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of the oxidised and reduced acidic cytochrome c3from Desulfovibrio africanus.
J.Mol.Biol., 290, 1999
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3CAR
 | | REDUCED STRUCTURE OF THE ACIDIC CYTOCHROME C3 FROM DESULFOVIBRIO AFRICANUS | | 分子名称: | ARSENIC, CYTOCHROME C3, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Norager, S, Legrand, P, Pieulle, L, Hatchikian, C, Roth, M. | | 登録日 | 1998-11-17 | | 公開日 | 2000-07-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the oxidised and reduced acidic cytochrome c3from Desulfovibrio africanus.
J.Mol.Biol., 290, 1999
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1OAO
 | | NiZn[Fe4S4] and NiNi[Fe4S4] clusters in closed and open alpha subunits of acetyl-CoA synthase/carbon monoxide dehydrogenase | | 分子名称: | ACETATE ION, BICARBONATE ION, CARBON MONOXIDE DEHYDROGENASE/ACETYL-COA SYNTHASE SUBUNIT ALPHA, ... | | 著者 | Darnault, C, Volbeda, A, Kim, E.J, Legrand, P, Vernede, X, Lindahl, P.A, Fontecilla-Camps, J.C. | | 登録日 | 2003-01-20 | | 公開日 | 2003-04-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Ni-Zn-[Fe4-S4] and Ni-Ni-[Fe4-S4] Clusters in Closed and Open Alpha Subunits of Acetyl-Coa Synthase/Carbon Monoxide Dehydrogenase
Nat.Struct.Biol., 10, 2003
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7NXQ
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