3FJ8
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3FJA
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3FJD
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3FJJ
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3FJC
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5UMV
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3FGM
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3FJF
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3FJE
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3FJH
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2G3R
| Crystal Structure of 53BP1 tandem tudor domains at 1.2 A resolution | Descriptor: | SULFATE ION, Tumor suppressor p53-binding protein 1 | Authors: | Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G. | Deposit date: | 2006-02-20 | Release date: | 2007-01-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair. Cell(Cambridge,Mass.), 127, 2006
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2PNL
| Crystal structure of VP4 protease from infectious pancreatic necrosis virus (IPNV) in space group P1 | Descriptor: | GUANIDINE, Protease VP4 | Authors: | Paetzel, M, Lee, J, Feldman, A.R, Delmas, B. | Deposit date: | 2007-04-24 | Release date: | 2007-06-05 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction. J.Biol.Chem., 282, 2007
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2PNM
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3S2P
| Crystal structure of CDK2 with a 2-aminopyrimidine compound | Descriptor: | (3S,4S)-1-{3-[2-amino-6-(propan-2-yl)pyrimidin-4-yl]-4-hydroxyphenyl}pyrrolidine-3,4-diol, Cyclin-dependent kinase 2 | Authors: | Kim, K.-H, Lee, J, Jeong, S. | Deposit date: | 2011-05-17 | Release date: | 2011-07-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors Bioorg.Med.Chem.Lett., 21, 2011
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7WBK
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7WBM
| Crystal structure of Legionella pneumophila effector protein Lpg0081 | Descriptor: | Lpg0081, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | Authors: | Lee, J, Kim, H, Oh, B.H. | Deposit date: | 2021-12-17 | Release date: | 2022-06-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Reversible modification of mitochondrial ADP/ATP translocases by paired Legionella effector proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
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2F8P
| Crystal structure of obelin following Ca2+ triggered bioluminescence suggests neutral coelenteramide as the primary excited state | Descriptor: | CALCIUM ION, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, Obelin | Authors: | Liu, Z.J, Stepanyuk, G.A, Vysotski, E.S, Lee, J, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2005-12-03 | Release date: | 2006-02-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structure of obelin after Ca2+-triggered bioluminescence suggests neutral coelenteramide as the primary excited state. Proc.Natl.Acad.Sci.Usa, 103, 2006
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3KPX
| Crystal Structure Analysis of photoprotein clytin | Descriptor: | Apophotoprotein clytin-3, C2-HYDROPEROXY-COELENTERAZINE, CALCIUM ION | Authors: | Titushin, M.S, Li, Y, Stepanyuk, G.A, Wang, B.-C, Lee, J, Vysotski, E.S, Liu, Z.-J. | Deposit date: | 2009-11-17 | Release date: | 2010-10-06 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.899 Å) | Cite: | NMR derived topology of a GFP-photoprotein energy transfer complex J.Biol.Chem., 285, 2010
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2FB8
| Structure of the B-Raf kinase domain bound to SB-590885 | Descriptor: | (1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIME, B-Raf proto-oncogene serine/threonine-protein kinase | Authors: | Lougheed, J.C, Lee, J, Chau, D.C, Stout, T.J. | Deposit date: | 2005-12-08 | Release date: | 2006-12-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885. Cancer Res., 66, 2006
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3TUD
| Crystal structure of SYK kinase domain with N-(4-methyl-3-(8-methyl-7-oxo-2-(phenylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)phenyl)-3-(trifluoromethyl)benzamide | Descriptor: | N-{4-methyl-3-[8-methyl-7-oxo-2-(phenylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]phenyl}-3-(trifluoromethyl)benzamide, Tyrosine-protein kinase SYK | Authors: | Lovering, F, McDonald, J, Whitlock, G, Glossop, P, Phillips, C, Sabnis, Y, Ryan, M, Fitz, L, Lee, J, Chang, J.S, Han, S, Kurumbail, R, Thorarenson, A. | Deposit date: | 2011-09-16 | Release date: | 2012-08-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Identification of Type-II Inhibitors Using Kinase Structures. Chem.Biol.Drug Des., 80, 2012
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2RVC
| Solution structure of Zalpha domain of goldfish ZBP-containing protein kinase | Descriptor: | Interferon-inducible and double-stranded-dependent eIF-2kinase | Authors: | Lee, A, Park, C, Park, J, Kwon, M, Choi, Y, Kim, K, Choi, B, Lee, J. | Deposit date: | 2015-07-08 | Release date: | 2016-02-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the Z-DNA binding domain of PKR-like protein kinase from Carassius auratus and quantitative analyses of the intermediate complex during B-Z transition. Nucleic Acids Res., 44, 2016
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1SL7
| Crystal structure of calcium-loaded apo-obelin from Obelia longissima | Descriptor: | CALCIUM ION, Obelin | Authors: | Deng, L, Markova, S.V, Vysotski, E.S, Liu, Z.J, Lee, J, Rose, J, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-03-05 | Release date: | 2004-12-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin. Protein Sci., 14, 2005
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1S36
| Crystal structure of a Ca2+-discharged photoprotein: Implications for the mechanisms of the calcium trigger and the bioluminescence | Descriptor: | CHLORIDE ION, GLYCEROL, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, ... | Authors: | Deng, L, Markova, S.V, Vysotski, E.S, Liu, Z.-J, Lee, J, Rose, J, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-01-12 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structure of a Ca2+-discharged photoprotein: implications for mechanisms of the calcium trigger and bioluminescence J.Biol.Chem., 279, 2004
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1SL9
| Obelin from Obelia longissima | Descriptor: | C2-HYDROPEROXY-COELENTERAZINE, Obelin | Authors: | Deng, L, Markova, S, Vysotski, E, Liu, Z.-J, Lee, J, Rose, J, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-03-05 | Release date: | 2005-07-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | Obelin from Obelia longissima To be Published
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1SL8
| Calcium-loaded apo-aequorin from Aequorea victoria | Descriptor: | Aequorin 1, CALCIUM ION | Authors: | Deng, L, Markova, S.V, Vysotski, E.S, Liu, Z.J, Lee, J, Rose, J, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-03-05 | Release date: | 2004-12-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | All three Ca2+-binding loops of photoproteins bind calcium ions: The crystal structures of calcium-loaded apo-aequorin and apo-obelin. Protein Sci., 14, 2005
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