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6B4V
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BU of 6b4v by Molmil
Antibiotic blasticidin S and E. coli release factor 1 bound to the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Svidritskiy, E, Korostelev, A.A.
Deposit date:2017-09-27
Release date:2018-02-07
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Mechanism of Inhibition of Translation Termination by Blasticidin S.
J. Mol. Biol., 430, 2018
6AWC
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BU of 6awc by Molmil
Structure of 30S ribosomal subunit and RNA polymerase complex in rotated state
Descriptor: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ...
Authors:Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
Deposit date:2017-09-05
Release date:2017-10-18
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6BU8
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BU of 6bu8 by Molmil
70S ribosome with S1 domains 1 and 2 (Class 1)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
Authors:Loveland, A.B, Korostelev, A.A.
Deposit date:2017-12-08
Release date:2018-01-31
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural dynamics of protein S1 on the 70S ribosome visualized by ensemble cryo-EM.
Methods, 137, 2018
6BOH
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BU of 6boh by Molmil
Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Svidritskiy, E, Korostelev, A.A.
Deposit date:2017-11-20
Release date:2018-05-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Conformational Control of Translation Termination on the 70S Ribosome.
Structure, 26, 2018
6BOK
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BU of 6bok by Molmil
E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Svidritskiy, E, Korostelev, A.A.
Deposit date:2017-11-20
Release date:2018-05-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Conformational Control of Translation Termination on the 70S Ribosome.
Structure, 26, 2018
3J6Y
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BU of 3j6y by Molmil
S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I)
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
Authors:Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A.
Deposit date:2014-04-16
Release date:2014-06-11
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J6X
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BU of 3j6x by Molmil
S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II)
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
Authors:Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A.
Deposit date:2014-04-16
Release date:2014-06-11
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J78
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BU of 3j78 by Molmil
Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class I - non-rotated ribosome with 2 tRNAs)
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
Authors:Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A.
Deposit date:2014-05-29
Release date:2014-08-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
3J77
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BU of 3j77 by Molmil
Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class II - rotated ribosome with 1 tRNA)
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
Authors:Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A.
Deposit date:2014-05-29
Release date:2014-08-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
7ST2
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BU of 7st2 by Molmil
Post translocation, non-rotated 70S ribosome with EF-G dissociated (Structure VII)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2021-11-11
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7SSW
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BU of 7ssw by Molmil
Late translocation intermediate with EF-G dissociated (Structure VI)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2021-11-11
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7SSL
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BU of 7ssl by Molmil
Pre translocation intermediate with EF-G bound to GDP and Pi (Structure III)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2021-11-11
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7ST7
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BU of 7st7 by Molmil
Pre translocation intermediate stalled with viomycin and bound with EF-G in a GDP and Pi state (Structure III-vio)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2021-11-12
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7SSO
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BU of 7sso by Molmil
Pre translocation 70S ribosome with A/A and P/E tRNA (Structure II-A)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2021-11-11
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7SS9
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BU of 7ss9 by Molmil
Late translocation intermediate with EF-G partially dissociated (Structure V)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Loveland, A.B, Gamper, H.B, Hou, Y, Korostelev, A.A.
Deposit date:2021-11-10
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7SSN
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BU of 7ssn by Molmil
Pre translocation 70S ribosome with A/P* and P/E tRNA (Structure II-B)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2021-11-11
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7SSD
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BU of 7ssd by Molmil
Mid translocation intermediate with EF-G bound with GDP (Structure IV)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2021-11-10
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7ST6
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BU of 7st6 by Molmil
Pre translocation, non-rotated 70S ribosome (Structure I)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Korostelev, A.A.
Deposit date:2021-11-12
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7TOR
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BU of 7tor by Molmil
Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Nat Commun, 13, 2022
7TOP
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BU of 7top by Molmil
Yeast 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein PR20
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Nat Commun, 13, 2022
7TOO
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BU of 7too by Molmil
Yeast 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Nat Commun, 13, 2022
7TOQ
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BU of 7toq by Molmil
Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein poly-PR
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Nat Commun, 13, 2022
7TOS
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BU of 7tos by Molmil
E. coli 70S ribosomes bound with the ALS/FTD-associated dipeptide repeat protein PR20
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Nat Commun, 13, 2022
3FBV
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BU of 3fbv by Molmil
Crystal structure of the oligomer formed by the kinase-ribonuclease domain of Ire1
Descriptor: N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, Serine/threonine-protein kinase/endoribonuclease IRE1
Authors:Korennykh, A.V, Egea, P.F, Korostelev, A.A, Finer-Moore, J, Zhang, C, Shokat, K.M, Stroud, R.M, Walter, P.
Deposit date:2008-11-19
Release date:2008-12-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The unfolded protein response signals through high-order assembly of Ire1.
Nature, 457, 2009
5J4D
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BU of 5j4d by Molmil
E. coli release factor 1 bound to the 70S ribosome in response to a pseudouridylated stop codon
Descriptor: 16S ribosomal RNA, 25S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Svidritskiy, E, Korostelev, A.A.
Deposit date:2016-03-31
Release date:2016-05-18
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Translation Termination on a Pseudouridylated Stop Codon.
J.Mol.Biol., 428, 2016

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