8D9F
| gRAMP-TPR-CHAT (Craspase) | Descriptor: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D9H
| gRAMP-TPR-CHAT match PFS target RNA(Craspase) | Descriptor: | CHAT domain protein, PHOSPHATE ION, RAMP superfamily protein, ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D97
| Apo gRAMP | Descriptor: | RAMP superfamily protein, RNA (42-MER), ZINC ION | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D9I
| gRAMP non-matching PFS-with Mg | Descriptor: | RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*A)-3'), ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D9E
| gRAMP-match PFS target | Descriptor: | RAMP superfamily protein, RNA (36-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*GP*UP*A)-3'), ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D9G
| gRAMP-TPR-CHAT Non match PFS target RNA(Craspase) | Descriptor: | CHAT domain protein, RAMP superfamily protein, RNA (36-MER), ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-09 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
8D8N
| gRAMP non-match PFS target RNA | Descriptor: | RAMP superfamily protein, RNA (35-MER), RNA (5'-R(P*UP*CP*CP*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*AP*CP*A)-3'), ... | Authors: | Hu, C, Nam, K.H, Schuler, G, Ke, A. | Deposit date: | 2022-06-08 | Release date: | 2022-08-31 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Craspase is a CRISPR RNA-guided, RNA-activated protease. Science, 377, 2022
|
|
4Y1M
| |
4Y1I
| Lactococcus lactis yybP-ykoY Mn riboswitch bound to Mn2+ | Descriptor: | BARIUM ION, GUANOSINE-5'-TRIPHOSPHATE, Lactococcus lactis yybP-ykoY riboswitch, ... | Authors: | Price, I.R, Ke, A. | Deposit date: | 2015-02-07 | Release date: | 2015-04-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Mn(2+)-Sensing Mechanisms of yybP-ykoY Orphan Riboswitches. Mol.Cell, 57, 2015
|
|
4Y1J
| |
3R4F
| Prohead RNA | Descriptor: | MAGNESIUM ION, pRNA | Authors: | Ding, F, Lu, C, Zhano, W, Rajashankar, K.R, Anderson, D.L, Jardine, P.J, Grimes, S, Ke, A. | Deposit date: | 2011-03-17 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure and assembly of the essential RNA ring component of a viral DNA packaging motor. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
8CSZ
| IscB and wRNA bound to Target DNA | Descriptor: | DNA non-target strand, DNA target strand, IscB, ... | Authors: | Schuler, G.A, Hu, C, Ke, A. | Deposit date: | 2022-05-13 | Release date: | 2022-06-15 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9. Science, 376, 2022
|
|
8CTL
| IscB and wRNA bound to Target DNA (locked state) | Descriptor: | DNA non-target strand, DNA target strand, IscB, ... | Authors: | Schuler, G.A, Hu, C, Ke, A. | Deposit date: | 2022-05-16 | Release date: | 2022-06-15 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9. Science, 376, 2022
|
|
8G9U
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | CRISPR-associated protein, Csd1 family, Csd2 family, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-22 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
|
|
8G9T
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | AcrIC9, Cas11, Cas5, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-22 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
|
|
8G9S
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | AcrIC8, Cas11, Cas5, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-22 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
|
|
8GAF
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | Cas11, Cas5, Cas7, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-22 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
|
|
8GAM
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | Cas11, Cas5, Cas7, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-23 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
|
|
8GAN
| Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | Cas11, Cas5, Cas7, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-23 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
|
|
2XXA
| The Crystal Structure of the Signal Recognition Particle (SRP) in Complex with its Receptor(SR) | Descriptor: | 4.5S RNA, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Ataide, S.F, Schmitz, N, Shen, K, Ke, A, Shan, S, Doudna, J.A, Ban, N. | Deposit date: | 2010-11-09 | Release date: | 2011-03-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.94 Å) | Cite: | The Crystal Structure of the Signal Recognition Particle in Complex with its Receptor. Science, 331, 2011
|
|
7UTN
| IscB and wRNA bound to Target DNA | Descriptor: | DNA non-target strand, DNA target strand, IscB, ... | Authors: | Schuler, G.A, Hu, C, Ke, A. | Deposit date: | 2022-04-27 | Release date: | 2022-06-15 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Structural basis for RNA-guided DNA cleavage by IscB-omega RNA and mechanistic comparison with Cas9. Science, 376, 2022
|
|
5H9E
| Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target (32-nt spacer) at 3.20 angstrom resolution. | Descriptor: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | Authors: | Hayes, R.P, Xiao, Y, Ding, F, van Erp, P.B.G, Rajashankar, K, Bailey, S, Wiedenheft, B, Ke, A. | Deposit date: | 2015-12-28 | Release date: | 2016-02-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli. Nature, 530, 2016
|
|
5H9F
| Crystal structure of E. coli Cascade bound to a PAM-containing dsDNA target at 2.45 angstrom resolution. | Descriptor: | CRISPR system Cascade subunit CasA, CRISPR system Cascade subunit CasB, CRISPR system Cascade subunit CasC, ... | Authors: | Hayes, R.P, Xiao, Y, Ding, F, van Erp, P.B.G, Rajashankar, K, Bailey, S, Wiedenheft, B, Ke, A. | Deposit date: | 2015-12-28 | Release date: | 2016-02-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli. Nature, 530, 2016
|
|
6N2V
| |
3L7Z
| Crystal structure of the S. solfataricus archaeal exosome | Descriptor: | Probable exosome complex RNA-binding protein 1, Probable exosome complex exonuclease 1, Probable exosome complex exonuclease 2, ... | Authors: | Lu, C, Ding, F, Ke, A. | Deposit date: | 2009-12-29 | Release date: | 2010-06-23 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Crystal structure of the S. solfataricus archaeal exosome reveals conformational flexibility in the RNA-binding ring. Plos One, 5, 2010
|
|