4QKN
 
 | | Crystal structure of FTO bound to a selective inhibitor | | 分子名称: | 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, GLYCEROL, ... | | 著者 | Yang, C.-G, Huang, Y, Gan, J. | | 登録日 | 2014-06-07 | | 公開日 | 2014-12-03 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5.
Nucleic Acids Res., 43, 2015
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5ZMD
 | | Crystal structure of FTO in complex with m6dA modified ssDNA | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase FTO, DNA (5'-D(P*TP*CP*TP*(6MA)P*TP*AP*TP*CP*G)-3'), MANGANESE (II) ION, ... | | 著者 | Zhang, X, Wei, L.H, Luo, J, Xiao, Y, Liu, J, Zhang, W, Zhang, L, Jia, G.F. | | 登録日 | 2018-04-02 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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