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Structure of yeast oxysterol binding protein Osh4 in complex with ergosterol
分子名称:	ERGOSTEROL, KES1 protein, LEAD (II) ION
著者	Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H.
登録日	2005-04-26
公開日	2005-09-06
最終更新日	2023-08-23
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005

1ZHY

Structure of yeast oxysterol binding protein Osh4 in complex with cholesterol
分子名称:	CHOLESTEROL, KES1 protein, LEAD (II) ION
著者	Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H.
登録日	2005-04-26
公開日	2005-09-06
最終更新日	2023-08-23
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005

1ZHT

Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
分子名称:	7-HYDROXYCHOLESTEROL, KES1 protein
著者	Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H.
登録日	2005-04-26
公開日	2005-09-06
最終更新日	2023-08-23
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005

1Z2O

Inositol 1,3,4-trisphosphate 5/6-Kinase in complex with mg2+/ADP/Ins(1,3,4,6)P4
分子名称:	(1S,3R,4R,6S)-1,3,4,6-TETRAPKISPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者	Miller, G.J, Wilson, M.P, Majerus, P.W, Hurley, J.H.
登録日	2005-03-08
公開日	2005-04-19
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.24 Å)
主引用文献	Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase. Mol.Cell, 18, 2005

1ZB1

Structure basis for endosomal targeting by the Bro1 domain
分子名称:	BRO1 protein
著者	Kim, J, Sitaraman, S, Hierro, A, Beach, B.M, Odorizzi, G, Hurley, J.H.
登録日	2005-04-07
公開日	2005-06-14
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Structural basis for endosomal targeting by the Bro1 domain. Dev.Cell, 8, 2005

1JUQ

GGA3 VHS domain complexed with C-terminal peptide from cation-dependent Mannose 6-phosphate receptor
分子名称:	ADP-RIBOSYLATION FACTOR BINDING PROTEIN GGA3, Cation-dependent mannose-6-phosphate receptor
著者	Misra, S, Puertollano, R, Bonifacino, J.S, Hurley, J.H.
登録日	2001-08-26
公開日	2002-02-27
最終更新日	2016-10-12
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature, 415, 2002

1JPL

GGA3 VHS domain complexed with C-terminal peptide from cation-independent mannose 6-phosphate receptor
分子名称:	ADP-RIBOSYLATION FACTOR BINDING PROTEIN GGA3, Cation-Independent Mannose 6-phosphate receptor
著者	Misra, S, Puertollano, R, Bonifacino, J.S, Hurley, J.H.
登録日	2001-08-02
公開日	2002-02-27
最終更新日	2011-07-13
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature, 415, 2002

1LF8

Complex of GGA3-VHS Domain and CI-MPR C-terminal Phosphopeptide
分子名称:	ADP-ribosylation factor binding protein GGA3, Cation-independent mannose-6-phosphate receptor
著者	Kato, Y, Misra, S, Puertollano, R, Hurley, J.H, Bonifacino, J.S.
登録日	2002-04-10
公開日	2002-06-26
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Phosphoregulation of sorting signal-VHS domain interactions by a direct electrostatic mechanism. Nat.Struct.Biol., 9, 2002

1MN3

Cue domain of yeast Vps9p
分子名称:	Vacuolar protein sorting-associated protein VPS9
著者	Prag, G, Misra, S, Jones, E, Ghirlando, R, Davies, B.A, Horazdovsky, B.F, Hurley, J.H.
登録日	2002-09-04
公開日	2003-06-10
最終更新日	2021-10-27
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Mechanism of Ubiquitin Recognition by the CUE Domain of Vps9p Cell(Cambridge,Mass.), 113, 2003

1MLV

Structure and Catalytic Mechanism of a SET Domain Protein Methyltransferase
分子名称:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ribulose-1,5 biphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者	Trievel, R.C, Beach, B.M, Dirk, L.M.A, Houtz, R.L, Hurley, J.H.
登録日	2002-08-30
公開日	2002-10-30
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Structure and catalytic mechanism of a SET domain protein methyltransferase. Cell(Cambridge,Mass.), 111, 2002

1NWM

GAT domain of human GGA1
分子名称:	ADP-ribosylation factor binding protein GGA1
著者	Suer, S, Misra, S, Saidi, L.F, Hurley, J.H.
登録日	2003-02-06
公開日	2003-03-25
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Structure of the GAT domain of human GGA1: a syntaxin amino-terminal domain fold in an endosomal trafficking adaptor. Proc.Natl.Acad.Sci.USA, 100, 2003

1P0Y

Crystal structure of the SET domain of LSMT bound to MeLysine and AdoHcy
分子名称:	N-METHYL-LYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast, ...
著者	Trievel, R.C, Flynn, E.M, Houtz, R.L, Hurley, J.H.
登録日	2003-04-11
公開日	2003-07-01
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT Nat.Struct.Biol., 10, 2003

1P4U

CRYSTAL STRUCTURE OF GGA3 GAE DOMAIN IN COMPLEX WITH RABAPTIN-5 PEPTIDE
分子名称:	ADP-ribosylation factor binding protein GGA3, Rabaptin-5
著者	Miller, G.J, Mattera, R, Bonifacino, J.S, Hurley, J.H.
登録日	2003-04-24
公開日	2003-07-29
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	RECOGNITION OF ACCESSORY PROTEIN MOTIFS BY THE GAMMA-ADAPTIN EAR DOMAIN OF GGA3 Nat.Struct.Biol., 10, 2003

7JTL

Structure of SARS-CoV-2 ORF8 accessory protein
分子名称:	ORF8 protein, SODIUM ION
著者	Flower, T.G, Buffalo, C.Z, Hooy, R.M, Allaire, M, Ren, X, Hurley, J.H.
登録日	2020-08-18
公開日	2020-08-26
最終更新日	2021-02-10
実験手法	X-RAY DIFFRACTION (2.04 Å)
主引用文献	Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein. Proc.Natl.Acad.Sci.USA, 118, 2021

5PTP

STRUCTURE OF HYDROLASE (SERINE PROTEINASE)
分子名称:	BETA TRYPSIN, CALCIUM ION
著者	Stroud, R.M, Finer-Moore, J.
登録日	1997-03-31
公開日	1997-07-07
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (1.34 Å)
主引用文献	Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction. Proteins, 12, 1992

5L1Z

TAR complex with HIV-1 Tat-AFF4-P-TEFb
分子名称:	AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ...
著者	Schulze-Gahmen, U, Hurley, J.
登録日	2016-07-29
公開日	2016-10-26
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (5.9 Å)
主引用文献	Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex. Elife, 5, 2016

7R4H

phospho-STING binding to adaptor protein complex-1
分子名称:	ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者	Xu, P, Ablasser, A.
登録日	2022-02-08
公開日	2022-09-14
最終更新日	2022-11-09
実験手法	ELECTRON MICROSCOPY (2.34 Å)
主引用文献	Clathrin-associated AP-1 controls termination of STING signalling. Nature, 610, 2022

7UX2

cryo-EM structure of the Raptor-TFEB-Rag-Ragulator complex
分子名称:	GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者	Cui, Z, Hurley, J.
登録日	2022-05-04
公開日	2022-11-30
最終更新日	2023-03-01
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023

7UXC

cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex with symmetry expansion
分子名称:	GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者	Cui, Z, Hurley, J.
登録日	2022-05-05
公開日	2022-11-30
最終更新日	2023-03-01
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023

7UXH

cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex
分子名称:	GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
著者	Cui, Z, Hurley, J.
登録日	2022-05-05
公開日	2022-11-30
最終更新日	2023-03-01
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023

4N7H

Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3
分子名称:	Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE
著者	Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J.
登録日	2013-10-15
公開日	2014-01-08
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.698 Å)
主引用文献	Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3). J.Biol.Chem., 289, 2014

4N7F

Crystal structure of 3rd WW domain of human Nedd4-1
分子名称:	E3 ubiquitin-protein ligase NEDD4
著者	Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J.
登録日	2013-10-15
公開日	2014-01-08
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.102 Å)
主引用文献	Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3). J.Biol.Chem., 289, 2014

1BL5

ISOCITRATE DEHYDROGENASE FROM E. COLI SINGLE TURNOVER LAUE STRUCTURE OF RATE-LIMITED PRODUCT COMPLEX, 10 MSEC TIME RESOLUTION
分子名称:	2-OXOGLUTARIC ACID, ISOCITRATE DEHYDROGENASE, MAGNESIUM ION, ...
著者	Stoddard, B.L, Cohen, B, Brubaker, M, Mesecar, A, Koshland Junior, D.E.
登録日	1998-07-23
公開日	1999-05-04
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Millisecond Laue structures of an enzyme-product complex using photocaged substrate analogs. Nat.Struct.Biol., 5, 1998

4R7X

Crystal structure of N-lobe of human ARRDC3(1-180)
分子名称:	Arrestin domain-containing protein 3, PHOSPHATE ION
著者	Qi, S, Hurley, J.
登録日	2014-08-28
公開日	2014-10-01
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.61 Å)
主引用文献	Insights into beta 2-adrenergic receptor binding from structures of the N-terminal lobe of ARRDC3. Protein Sci., 23, 2014

1IDE

ISOCITRATE DEHYDROGENASE Y160F MUTANT STEADY-STATE INTERMEDIATE COMPLEX (LAUE DETERMINATION)
分子名称:	ISOCITRATE DEHYDROGENASE, ISOCITRIC ACID, MAGNESIUM ION, ...
著者	Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L.
登録日	1995-01-18
公開日	1996-03-08
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase. Science, 268, 1995

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