7DZY
 
 | | Spike protein from SARS-CoV2 with Fab fragment of enhancing antibody 2490 | | 分子名称: | Fab Heavy chain of enhancing antibody 2490, Fab light chain of enhancing antibody 2490, Spike glycoprotein | | 著者 | Liu, Y, Soh, W.T, Li, S, Kishikawa, J, Hirose, M, Kato, T, Standley, D, Okada, M, Arase, H. | | 登録日 | 2021-01-26 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies.
Cell, 184, 2021
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7DZX
 | | Spike protein from SARS-CoV2 with Fab fragment of enhancing antibody 8D2 | | 分子名称: | Fab Heavy chain of enhancing antibody, Fab light chain of enhancing antibody, Spike glycoprotein | | 著者 | Liu, Y, Soh, W.T, Li, S, Kishikawa, J, Hirose, M, Kato, T, Standley, D, Okada, M, Arase, H. | | 登録日 | 2021-01-26 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies.
Cell, 184, 2021
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7DZW
 | | Apo spike protein from SARS-CoV2 | | 分子名称: | Spike glycoprotein | | 著者 | Liu, Y, Soh, W.T, Li, S, Kishikawa, J, Hirose, M, Kato, T, Standley, D, Okada, M, Arase, H. | | 登録日 | 2021-01-26 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies.
Cell, 184, 2021
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6LXV
 | | Cryo-EM structure of phosphoketolase from Bifidobacterium longum | | 分子名称: | CALCIUM ION, Phosphoketolase, THIAMINE DIPHOSPHATE | | 著者 | Nakata, K, Miyazaki, N, Yamaguchi, H, Hirose, M, Miyano, H, Mizukoshi, T, Kashiwagi, T, Iwasaki, K. | | 登録日 | 2020-02-12 | | 公開日 | 2021-02-17 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | | 主引用文献 | High-resolution structure of phosphoketolase from Bifidobacterium longum determined by cryo-EM single-particle analysis.
J.Struct.Biol., 214, 2022
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3WR7
 | | Crystal Structure of Spermidine Acetyltransferase from Escherichia coli | | 分子名称: | COENZYME A, SPERMIDINE, Spermidine N1-acetyltransferase | | 著者 | Sugiyama, S, Ishikawa, S, Tomitori, S, Niiyama, M, Hirose, M, Miyazaki, Y, Higashi, K, Adachi, H, Takano, K, Murakami, S, Inoue, T, Mori, Y, Kashiwagi, K, Igarashi, K, Matsumura, H. | | 登録日 | 2014-02-20 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular mechanism underlying promiscuous polyamine recognition by spermidine acetyltransferase
Int.J.Biochem.Cell Biol., 76, 2016
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5AVG
 | | The 0.95 angstrom structure of thaumatin crystallized in high-strength agarose hydrogel | | 分子名称: | Thaumatin-1 | | 著者 | Sugiyama, S, Shimizu, N, Maruyama, M, Sazaki, G, Hirose, M, Adachi, H, Takano, K, Murakami, S, Inoue, T, Mori, Y, Matsumura, H. | | 登録日 | 2015-06-16 | | 公開日 | 2015-07-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Growth of protein crystals in hydrogels prevents osmotic shock
J.Am.Chem.Soc., 134, 2012
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3WVM
 | | The 0.88 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with stearic acid | | 分子名称: | Fatty acid-binding protein, heart, HEXAETHYLENE GLYCOL, ... | | 著者 | Sugiyama, S, Matsuoka, S, Mizohata, E, Matsuoka, D, Ishida, H, Hirose, M, Kakinouchi, K, Hara, T, Matsumura, H, Murakami, S, Inoue, T, Murata, M. | | 登録日 | 2014-05-25 | | 公開日 | 2015-01-28 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (0.88 Å) | | 主引用文献 | Water-mediated recognition of simple alkyl chains by heart-type fatty-acid-binding protein.
Angew.Chem.Int.Ed.Engl., 54, 2015
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2ZQ3
 | | The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.6 angstroms resolution | | 分子名称: | Lysozyme C, SODIUM ION | | 著者 | Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Hirose, M. | | 登録日 | 2008-08-03 | | 公開日 | 2008-09-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution
To be Published
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2ZQ4
 | | The crystal structure of the orthorhombic form of hen egg white lysozyme at 2.0 angstroms resolution | | 分子名称: | Lysozyme C | | 著者 | Aibara, S, Suzuki, A, Kidera, A, Shibata, K, Yamane, T, Hirose, M. | | 登録日 | 2008-08-03 | | 公開日 | 2008-09-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of the orthorhombic form of hen egg white lysozyme at 1.5 angstroms resolution
To be Published
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4FC0
 | | Crystal Structure of Human Kinase Domain of B-raf with a DFG-out Inhibitor | | 分子名称: | 2-chloro-3-[(2-cyanopropan-2-yl)oxy]-N-{5-[{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}(methyl)amino]-2-fluorophenyl}benzamide, Serine/threonine-protein kinase B-raf | | 著者 | Yano, J.K, Aertgeerts, K. | | 登録日 | 2012-05-23 | | 公開日 | 2014-01-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives.
Bioorg.Med.Chem., 20, 2012
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1EHA
 | | CRYSTAL STRUCTURE OF GLYCOSYLTREHALOSE TREHALOHYDROLASE FROM SULFOLOBUS SOLFATARICUS | | 分子名称: | GLYCOSYLTREHALOSE TREHALOHYDROLASE | | 著者 | Feese, M.D, Kato, Y, Tamada, T, Kato, M, Komeda, T, Kobayashi, K, Kuroki, R. | | 登録日 | 2000-02-19 | | 公開日 | 2001-02-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of glycosyltrehalose trehalohydrolase from the hyperthermophilic archaeum Sulfolobus solfataricus.
J.Mol.Biol., 301, 2000
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1EH9
 | | CRYSTAL STRUCTURE OF SULFOLOBUS SOLFATARICUS GLYCOSYLTREHALOSE TREHALOHYDROLASE | | 分子名称: | GLYCOSYLTREHALOSE TREHALOHYDROLASE | | 著者 | Feese, M.D, Kato, Y, Tamada, T, Kato, M, Komeda, T, Kobayashi, K, Kuroki, R. | | 登録日 | 2000-02-19 | | 公開日 | 2001-02-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of glycosyltrehalose trehalohydrolase from the hyperthermophilic archaeum Sulfolobus solfataricus.
J.Mol.Biol., 301, 2000
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4DBN
 | | Crystal Structure of the Kinase domain of Human B-raf with a [1,3]thiazolo[5,4-b]pyridine derivative | | 分子名称: | 2-chloro-3-(1-cyanocyclopropyl)-N-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)-2-fluorophenyl]benzamide, Serine/threonine-protein kinase B-raf | | 著者 | Yano, J.K, Aertgeerts, K. | | 登録日 | 2012-01-16 | | 公開日 | 2012-04-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds.
J.Med.Chem., 55, 2012
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7W71
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8X3H
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7CQD
 | | The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA14 tag inserted between the residues 235 and 236 | | 分子名称: | Heavy chain of antigen binding fragment, Fab of NZ-1, Light chain of antigen binding fragment, ... | | 著者 | Tamura-Sakaguchi, R, Aruga, R, Nogi, T. | | 登録日 | 2020-08-10 | | 公開日 | 2021-05-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope-tag insertion.
Acta Crystallogr D Struct Biol, 77, 2021
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7CQC
 | | The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA14 tag inserted between the residues 181 and 184 | | 分子名称: | Heavy chain of antigen binding fragment, Fab of NZ-1, Light chain of antigen binding fragment, ... | | 著者 | Aruga, R, Tamura-Sakaguchi, R, Nogi, T. | | 登録日 | 2020-08-10 | | 公開日 | 2021-05-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope-tag insertion.
Acta Crystallogr D Struct Biol, 77, 2021
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4KSP
 | | Crystal Structure of Human B-raf bound to a DFG-out Inhibitor TAK-632 | | 分子名称: | N-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide, Serine/threonine-protein kinase B-raf | | 著者 | Yano, J.K, Masanori, O. | | 登録日 | 2013-05-17 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | | 主引用文献 | Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives.
J.Med.Chem., 56, 2013
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4KSQ
 | | Crystal Structure of Human B-raf bound to a DFG-out Inhibitor 5B | | 分子名称: | N-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide, Serine/threonine-protein kinase B-raf | | 著者 | Yano, J.K, Masanori, O. | | 登録日 | 2013-05-17 | | 公開日 | 2013-07-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives.
J.Med.Chem., 56, 2013
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1ARB
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1ARC
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2YZ1
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1NNT
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7W6Z
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7W6X
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