1TQ6
| Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, interferon-inducible GTPase | Authors: | Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E. | Deposit date: | 2004-06-16 | Release date: | 2004-09-21 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases Mol.Cell, 15, 2004
|
|
1TQD
| Crystal structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, interferon-inducible GTPase | Authors: | Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E. | Deposit date: | 2004-06-17 | Release date: | 2004-09-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases Mol.Cell, 15, 2004
|
|
1TPZ
| Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E. | Deposit date: | 2004-06-16 | Release date: | 2004-09-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases Mol.Cell, 15, 2004
|
|
1TQ4
| Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, interferon-inducible GTPase | Authors: | Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E. | Deposit date: | 2004-06-16 | Release date: | 2004-09-21 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases Mol.Cell, 15, 2004
|
|
6HNF
| Structure in solution of human fibronectin type III-domain 14 | Descriptor: | Fibronectin | Authors: | Zhong, X, Arnolds, O, Krenczyk, O, Gajewski, J, Puetz, S, Herrmann, C, Stoll, R. | Deposit date: | 2018-09-14 | Release date: | 2018-10-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Structure in Solution of Fibronectin Type III Domain 14 Reveals Its Synergistic Heparin Binding Site. Biochemistry, 57, 2018
|
|
1RFH
| Solution structure of the C1 domain of Nore1, a novel Ras effector | Descriptor: | Ras association (RalGDS/AF-6) domain family 5, ZINC ION | Authors: | Guiberman, E, Wohlgemuth, S, Herrmann, C, Harjes, S, Mueller, K.H, Bayer, P. | Deposit date: | 2003-11-09 | Release date: | 2005-06-14 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | The solution structure of C1 domain of Nore1 To be Published
|
|
2RGF
| RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES | Descriptor: | RALGEF-RBD | Authors: | Geyer, M, Herrmann, C, Wittinghofer, A, Kalbitzer, H.R. | Deposit date: | 1997-02-13 | Release date: | 1998-03-04 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling. Nat.Struct.Biol., 4, 1997
|
|
2FNF
| C1 domain of Nore1 | Descriptor: | ZINC ION, putative Ras Effector Nore1 | Authors: | Harjes, E, Harjes, S, Wohlgemuth, S, Krieger, E, Herrmann, C, Muller, K.H, Bayer, P. | Deposit date: | 2006-01-11 | Release date: | 2006-02-07 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1. Structure, 14, 2006
|
|
4USJ
| N-acetylglutamate kinase from Arabidopsis thaliana in complex with PII from Chlamydomonas reinhardtii | Descriptor: | ACETYLGLUTAMATE KINASE, CHLOROPLASTIC, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Chellamuthu, V.R, Forchhammer, K, Hartmann, M.D. | Deposit date: | 2014-07-08 | Release date: | 2014-12-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | A Widespread Glutamine-Sensing Mechanism in the Plant Kingdom. Cell(Cambridge,Mass.), 159, 2014
|
|
4USI
| Nitrogen regulatory protein PII from Chlamydomonas reinhardtii in complex with MgATP and 2-oxoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Chellamuthu, V.R, Forchhammer, K, Hartmann, M.D. | Deposit date: | 2014-07-08 | Release date: | 2014-12-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | A Widespread Glutamine-Sensing Mechanism in the Plant Kingdom. Cell(Cambridge,Mass.), 159, 2014
|
|
1GUA
| HUMAN RAP1A, RESIDUES 1-167, DOUBLE MUTANT (E30D,K31E) COMPLEXED WITH GPPNHP AND THE RAS-BINDING-DOMAIN OF HUMAN C-RAF1, RESIDUES 51-131 | Descriptor: | C-RAF1, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Nassar, N, Wittinghofer, A. | Deposit date: | 1996-06-18 | Release date: | 1997-01-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Ras/Rap effector specificity determined by charge reversal. Nat.Struct.Biol., 3, 1996
|
|
4TQ2
| Structure of S-type Phycobiliprotein Lyase CPES from Guillardia theta | Descriptor: | HEXANE-1,6-DIOL, Putative phycoerythrin lyase | Authors: | Gasper, R, Overkamp, K.E, Frankenberg-Dinkel, N, Hofmann, E. | Deposit date: | 2014-06-10 | Release date: | 2014-08-13 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Insights into the Biosynthesis and Assembly of Cryptophycean Phycobiliproteins. J.Biol.Chem., 289, 2014
|
|
4USH
| |
4AK9
| |
6I4A
| Structure of P. aeruginosa LpxC with compound 18d: (2R)-N-Hydroxy-4-(6-((1-(hydroxymethyl)cyclopropyl)buta-1,3-diyn-1-yl)-3-oxo-1H-pyrrolo[1,2-c]imidazol-2(3H)-yl)-2-methyl-2-(methylsulfonyl)butanamide | Descriptor: | (2~{R})-4-[6-[4-[1-(hydroxymethyl)cyclopropyl]buta-1,3-diynyl]-3-oxidanylidene-1~{H}-pyrrolo[1,2-c]imidazol-2-yl]-2-methyl-2-methylsulfonyl-~{N}-oxidanyl-butanamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION | Authors: | Surivet, J.-P, Panchaud, P, Specklin, J.-L, Diethelm, S, Blumstein, A.-C, Gauvin, J.-C, Jacob, L, Masse, F, Mathieu, G, Mirre, A, Schmitt, C, Enderlin-Paput, M, Lange, R, Bur, D, Tidten-Luksch, N, Gnerre, C, Seeland, S, Hermann, C, Locher, H.H, Seiler, P, Mac Sweeney, A, Hubschwerlen, C, Ritz, D, Rueedi, G. | Deposit date: | 2018-11-09 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria. J.Med.Chem., 63, 2020
|
|
6I46
| Structure of P. aeruginosa LpxC with compound 8: (2RS)-4-(5-(2-Fluoro-4-methoxyphenyl)-2-oxooxazol-3(2H)-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide | Descriptor: | (2~{R})-4-[5-(2-fluoranyl-4-methoxy-phenyl)-2-oxidanylidene-1,3-oxazol-3-yl]-2-methyl-2-methylsulfonyl-~{N}-oxidanyl-butanamide, GLYCEROL, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... | Authors: | Surivet, J.-P, Panchaud, P, Specklin, J.-L, Diethelm, S, Blumstein, A.-C, Gauvin, J.-C, Jacob, L, Masse, F, Mathieu, G, Mirre, A, Schmitt, C, Enderlin-Paput, M, Lange, R, Bur, D, Tidten-Luksch, N, Gnerre, C, Seeland, S, Hermann, C, Locher, H.H, Seiler, P, Mac Sweeney, A, Hubschwerlen, C, Ritz, D, Rueedi, G. | Deposit date: | 2018-11-09 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria. J.Med.Chem., 63, 2020
|
|
6I48
| Structure of P. aeruginosa LpxC with compound 12: (2R)-4-(6-(2-Fluoro-4-methoxyphenyl)-3-oxo-1H-pyrrolo[1,2-c]imidazol-2(3H)-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide | Descriptor: | (2~{R})-4-[6-(2-fluoranyl-4-methoxy-phenyl)-3-oxidanylidene-1~{H}-pyrrolo[1,2-c]imidazol-2-yl]-2-methyl-2-methylsulfonyl-~{N}-oxidanyl-butanamide, 1,2-ETHANEDIOL, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... | Authors: | Surivet, J.-P, Panchaud, P, Specklin, J.-L, Diethelm, S, Blumstein, A.-C, Gauvin, J.-C, Jacob, L, Masse, F, Mathieu, G, Mirre, A, Schmitt, C, Enderlin-Paput, M, Lange, R, Bur, D, Tidten-Luksch, N, Gnerre, C, Seeland, S, Hermann, C, Locher, H.H, Seiler, P, Mac Sweeney, A, Hubschwerlen, C, Ritz, D, Rueedi, G. | Deposit date: | 2018-11-09 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.196 Å) | Cite: | Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria. J.Med.Chem., 63, 2020
|
|
6I47
| Structure of P. aeruginosa LpxC with compound 10: (2RS)-4-(5-(2-Fluoro-4-methoxyphenyl)-1-oxoisoindolin-2-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide | Descriptor: | (2~{R})-4-[6-(2-fluoranyl-4-methoxy-phenyl)-3-oxidanylidene-1~{H}-isoindol-2-yl]-2-methyl-2-methylsulfonyl-~{N}-oxidanyl-butanamide, (2~{S})-4-[6-(2-fluoranyl-4-methoxy-phenyl)-3-oxidanylidene-1~{H}-isoindol-2-yl]-2-methyl-2-methylsulfonyl-~{N}-oxidanyl-butanamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... | Authors: | Surivet, J.-P, Panchaud, P, Specklin, J.-L, Diethelm, S, Blumstein, A.-C, Gauvin, J.-C, Jacob, L, Masse, F, Mathieu, G, Mirre, A, Schmitt, C, Enderlin-Paput, M, Lange, R, Bur, D, Tidten-Luksch, N, Gnerre, C, Seeland, S, Hermann, C, Locher, H.H, Seiler, P, Mac Sweeney, A, Hubschwerlen, C, Ritz, D, Rueedi, G. | Deposit date: | 2018-11-09 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria. J.Med.Chem., 63, 2020
|
|
6I49
| Structure of P. aeruginosa LpxC with compound 17a: (2R)-N-Hydroxy-2-methyl-2-(methylsulfonyl)-4(6((4(morpholinomethyl)phenyl)ethynyl)-3-oxo-1H-pyrrolo[1,2-c]imidazol-2(3H)yl)butanamide | Descriptor: | (2~{R})-2-methyl-2-methylsulfonyl-4-[6-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]-3-oxidanylidene-1~{H}-pyrrolo[1,2-c]imidazol-2-yl]-~{N}-oxidanyl-butanamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ZINC ION | Authors: | Surivet, J.-P, Panchaud, P, Specklin, J.-L, Diethelm, S, Blumstein, A.-C, Gauvin, J.-C, Jacob, L, Masse, F, Mathieu, G, Mirre, A, Schmitt, C, Enderlin-Paput, M, Lange, R, Bur, D, Tidten-Luksch, N, Gnerre, C, Seeland, S, Hermann, C, Locher, H.H, Seiler, P, Mac Sweeney, A, Hubschwerlen, C, Ritz, D, Rueedi, G. | Deposit date: | 2018-11-09 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria. J.Med.Chem., 63, 2020
|
|
3G3T
| Crystal structure of a eukaryotic polyphosphate polymerase in complex with orthophosphate | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, Vacuolar transporter chaperone 4 | Authors: | Lenherr, E.D, Hothorn, M, Scheffzek, K. | Deposit date: | 2009-02-02 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase. Science, 324, 2009
|
|
3G3R
| |
3G3Q
| |
3G3O
| |
3G3U
| |
1RAX
| |