Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2C1E
DownloadVisualize
BU of 2c1e by Molmil
Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors.
分子名称: AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-14-(4-ETHOXY-4-OXOBUTANOYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN -16-OIC ACID, ...
著者Grutter, M.G.
登録日2005-09-14
公開日2006-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10.
J.Med.Chem., 49, 2006
3BWU
DownloadVisualize
BU of 3bwu by Molmil
Crystal structure of the ternary complex of FimD (N-Terminal Domain, FimDN) with FimC and the N-terminally truncated pilus subunit FimF (FimFt)
分子名称: 1,2-ETHANEDIOL, Chaperone protein fimC, DI(HYDROXYETHYL)ETHER, ...
著者Eidam, O, Grutter, M.G, Capitani, G.
登録日2008-01-10
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of the ternary FimC-FimF(t)-FimD(N) complex indicates conserved pilus chaperone-subunit complex recognition by the usher FimD
Febs Lett., 582, 2008
3THM
DownloadVisualize
BU of 3thm by Molmil
Crystal structure of Fas receptor extracellular domain in complex with Fab EP6b_B01
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fab EP6b_B01, ...
著者Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G.
登録日2011-08-19
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
3TJE
DownloadVisualize
BU of 3tje by Molmil
Crystal structure of Fas receptor extracellular domain in complex with Fab E09
分子名称: 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ...
著者Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G.
登録日2011-08-24
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
3PIU
DownloadVisualize
BU of 3piu by Molmil
High-resolution structure of native Malus domestica ACC synthase
分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 1-aminocyclopropane-1-carboxylate synthase
著者Scharer, M.A, Grutter, M.G, Capitani, G.
登録日2010-11-08
公開日2010-12-15
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural basis for reduced activity of 1-aminocyclopropane-1-carboxylate synthase affected by a mutation linked to andromonoecy.
Febs Lett., 585, 2011
3SQB
DownloadVisualize
BU of 3sqb by Molmil
Structure of the major type 1 pilus subunit FimA bound to the FimC chaperone
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Chaperone protein fimC, ...
著者Scharer, M.A, Eidam, O, Grutter, M.G, Glockshuber, R, Capitani, G.
登録日2011-07-05
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Quality control of disulfide bond formation in pilus subunits by the chaperone FimC.
Nat.Chem.Biol., 8, 2012
2XZT
DownloadVisualize
BU of 2xzt by Molmil
Caspase-3 in Complex with DARPin-3.4_I78S
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, CASPASE-3, DARPIN-3.4_I78S
著者Barandun, J, Schroeder, T, Mittl, P, Grutter, M.G.
登録日2010-11-29
公開日2011-12-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Caspase-3 in Complex with Darpin-3.4_I78S
To be Published
2XYP
DownloadVisualize
BU of 2xyp by Molmil
Caspase-3:CAS26049945
分子名称: CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17, PHENYLMETHYL N-[(2S)-4-CHLORO-3-OXO-1-PHENYL-BUTAN-2-YL]CARBAMATE
著者Ganesan, R, Jelakovic, S, Grutter, M.G, Mittl, P.R.
登録日2010-11-18
公開日2011-08-17
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.
Acta Crystallogr.,Sect.F, 67, 2011
2XYG
DownloadVisualize
BU of 2xyg by Molmil
Caspase-3:CAS329306
分子名称: CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17, N-[(2S)-4-chloro-3-oxo-1-phenyl-butan-2-yl]-4-methyl-benzenesulfonamide
著者Ganesan, R, Jelakovic, S, Grutter, M.G, Mittl, P.R.
登録日2010-11-17
公開日2011-08-17
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.
Acta Crystallogr.,Sect.F, 67, 2011
2XZD
DownloadVisualize
BU of 2xzd by Molmil
Caspase-3 in Complex with an Inhibitory DARPin-3.4
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CASPASE-3, ...
著者Barandun, J, Schroeder, T, Mittl, P, Grutter, M.G.
登録日2010-11-24
公開日2011-12-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Specific Inhibition of Caspase-3 by a Competitive Darpin: Molecular Mimicry between Native and Designed Inhibitors.
Structure, 21, 2013
2Y0B
DownloadVisualize
BU of 2y0b by Molmil
Caspase-3 in Complex with an Inhibitory DARPin-3.4_S76R
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CASPASE-3, ...
著者Barandun, J, Schroeder, T, Mittl, P, Grutter, M.G.
登録日2010-12-01
公開日2011-12-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Specific Inhibition of Caspase-3 by a Competitive Darpin: Molecular Mimicry between Native and Designed Inhibitors.
Structure, 21, 2013
2XYH
DownloadVisualize
BU of 2xyh by Molmil
Caspase-3:CAS60254719
分子名称: 5-CHLORO-4-OXOPENTANOIC ACID, CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17
著者Ganesan, R, Jelakovic, S, Grutter, M.G, Mittl, P.R.
登録日2010-11-17
公開日2011-08-17
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.
Acta Crystallogr.,Sect.F, 67, 2011
2Y1L
DownloadVisualize
BU of 2y1l by Molmil
Caspase-8 in Complex with DARPin-8.4
分子名称: 1,2-ETHANEDIOL, AC-IETD-CHO, CASPASE-8, ...
著者Barandun, J, Schroeder, T, Mittl, P.R.E, Grutter, M.G.
登録日2010-12-08
公開日2011-12-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Caspase-8 in Complex with Darpin-8.4
To be Published
3BFW
DownloadVisualize
BU of 3bfw by Molmil
Crystal structure of truncated FimG (FimGt) in complex with the donor strand peptide of FimF (DSF)
分子名称: Protein fimF, Protein fimG, YTTRIUM (III) ION
著者Eidam, O, Capitani, G, Grutter, M.G.
登録日2007-11-23
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Infinite Kinetic Stability against Dissociation of Supramolecular Protein Complexes through Donor Strand Complementation
Structure, 16, 2008
3BFQ
DownloadVisualize
BU of 3bfq by Molmil
Crystal structure of truncated FimG (FimGt) in complex with the donor strand peptide of FimF (DSF)
分子名称: COBALT (II) ION, Protein fimF, Protein fimG
著者Eidam, O, Capitani, G, Grutter, M.G.
登録日2007-11-23
公開日2008-03-04
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Infinite Kinetic Stability against Dissociation of Supramolecular Protein Complexes through Donor Strand Complementation
Structure, 16, 2008
3C7M
DownloadVisualize
BU of 3c7m by Molmil
Crystal structure of reduced DsbL
分子名称: CADMIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Stirnimann, C.U, Grimshaw, J.P.A, Glockshuber, R, Grutter, M.G, Capitani, G.
登録日2008-02-07
公開日2008-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli.
J.Mol.Biol., 380, 2008
1YNU
DownloadVisualize
BU of 1ynu by Molmil
Crystal structure of apple ACC synthase in complex with L-vinylglycine
分子名称: 1-aminocyclopropane-1-carboxylate synthase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[O-PHOSPHONOPYRIDOXYL]-AMINO- BUTYRIC ACID, ...
著者Capitani, G, Tschopp, M, Eliot, A.C, Kirsch, J.F, Grutter, M.G.
登録日2005-01-25
公開日2005-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of ACC synthase inactivated by the mechanism-based inhibitor L-vinylglycine.
Febs Lett., 579, 2005
1F9E
DownloadVisualize
BU of 1f9e by Molmil
CASPASE-8 SPECIFICITY PROBED AT SUBSITE S4: CRYSTAL STRUCTURE OF THE CASPASE-8-Z-DEVD-CHO
分子名称: (PHQ)DEVD, CASPASE-8 ALPHA CHAIN, CASPASE-8 BETA CHAIN
著者Blanchard, H, Donepudi, M, Tschopp, M, Kodandapani, L, Wu, J.C, Grutter, M.G.
登録日2000-07-10
公開日2001-07-10
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complex.
J.Mol.Biol., 302, 2000
2V12
DownloadVisualize
BU of 2v12 by Molmil
Crystal Structure of Renin with Inhibitor 8
分子名称: N-[(2S,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-7-METHYL-2-(1-METHYLETHYL)-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE, RENIN
著者Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
登録日2007-05-21
公開日2007-07-03
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V11
DownloadVisualize
BU of 2v11 by Molmil
Crystal Structure of Renin with Inhibitor 6
分子名称: (2S,4S,5R,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL 1-BENZYL-1H-INDOLE-3-CARBOXYLATE, RENIN
著者Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
登録日2007-05-21
公開日2007-07-03
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V0Z
DownloadVisualize
BU of 2v0z by Molmil
Crystal Structure of Renin with Inhibitor 10 (Aliskiren)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALISKIREN, RENIN
著者Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
登録日2007-05-21
公開日2007-07-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V16
DownloadVisualize
BU of 2v16 by Molmil
Crystal Structure of Renin with Inhibitor 3
分子名称: METHYL (3R)-1-[(5S,6S,8R)-5-AMINO-9-BUTYLAMINO-6-HYDROXY-3,3,8-TRIMETHYL-9-OXO-NONANOYL]-3,4-DIHYDRO-2H-QUINOLINE-3-CARBOXYLATE, RENIN
著者Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
登録日2007-05-22
公開日2008-07-08
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V13
DownloadVisualize
BU of 2v13 by Molmil
Crystal Structure of Renin with Inhibitor 7
分子名称: N-[(2R,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE, RENIN
著者Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
登録日2007-05-21
公開日2008-07-08
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V10
DownloadVisualize
BU of 2v10 by Molmil
Crystal Structure of Renin with Inhibitor 9
分子名称: (2R,4S,5S,7S)-5-AMINO-N-BUTYL-4-HYDROXY-7-[4-METHOXY-3-(3-METHOXYPROPOXY)BENZYL]-2,8-DIMETHYLNONANAMIDE, RENIN
著者Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
登録日2007-05-21
公開日2007-07-03
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
3MAD
DownloadVisualize
BU of 3mad by Molmil
Crystal structure of StSPL (symmetric form)
分子名称: PHOSPHATE ION, Sphingosine-1-phosphate lyase
著者Bourquin, F, Grutter, M.G, Capitani, G.
登録日2010-03-23
公開日2010-08-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism.
Structure, 18, 2010

219140

件を2024-05-01に公開中

PDB statisticsPDBj update infoContact PDBjnumon