1YO5
 
 | | Analysis of the 2.0A crystal structure of the protein-DNA complex of human PDEF Ets domain bound to the prostate specific antigen regulatory site | | Descriptor: | Enhancer site of Prostate Specific Antigen Promoter Region, SAM pointed domain containing ets transcription factor | | Authors: | Wang, Y, Feng, L, Said, M, Balderman, S, Fayazi, Z, Liu, Y, Ghosh, D, Gulick, A.M. | | Deposit date: | 2005-01-26 | | Release date: | 2005-05-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Analysis of the 2.0 A Crystal Structure of the Protein-DNA Complex of the Human PDEF Ets Domain Bound to the Prostate Specific Antigen Regulatory Site
Biochemistry, 44, 2005
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3ZJU
 | | Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3016 in the editing conformation | | Descriptor: | LEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, TRNALEU5 UAA ISOACCEPTOR | | Authors: | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | | Deposit date: | 2013-01-18 | | Release date: | 2013-04-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
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3ZJT
 | | Ternary complex of E.coli leucyl-tRNA synthetase, tRNA(Leu)574 and the benzoxaborole AN3017 in the editing conformation | | Descriptor: | LEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, TRNALEU5 UAA ISOACCEPTOR | | Authors: | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | | Deposit date: | 2013-01-18 | | Release date: | 2013-04-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
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3ZJV
 | | Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3213 in the editing conformation | | Descriptor: | LEUCINE--TRNA LIGASE, TRNALEU5 UAA ISOACCEPTOR | | Authors: | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | | Deposit date: | 2013-01-18 | | Release date: | 2013-04-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
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6R48
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6R46
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8FHT
 | | Cryo-EM structure of human NCC | | Descriptor: | CHLORIDE ION, SODIUM ION, Solute carrier family 12 member 3 | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-15 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHR
 | | Cryo-EM structure of human NCC (class 3-3) | | Descriptor: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHP
 | | Cryo-EM structure of human NCC (class 3-1) | | Descriptor: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHQ
 | | Cryo-EM structure of human NCC (class 3-2) | | Descriptor: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHO
 | | Cryo-EM structure of human NCC (class 1) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Polythiazide, SODIUM ION, ... | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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8FHN
 | | Cryo-EM structure of human NCC (class 2) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Polythiazide, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
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3BOB
 | | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 | | Descriptor: | CADMIUM ION, Cadmium-specific carbonic anhydrase | | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | | Deposit date: | 2007-12-17 | | Release date: | 2008-01-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
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3BOC
 | | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- zinc bound domain 2 (CDCA1-R2) | | Descriptor: | Cadmium-specific carbonic anhydrase, ZINC ION | | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | | Deposit date: | 2007-12-17 | | Release date: | 2008-01-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
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3BOE
 | | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 with acetate (CDCA1-R2) | | Descriptor: | ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase | | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | | Deposit date: | 2007-12-17 | | Release date: | 2008-01-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
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3BOJ
 | | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 without bound metal (CDCA1-R1) | | Descriptor: | ACETATE ION, Cadmium-specific carbonic anhydrase | | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | | Deposit date: | 2007-12-17 | | Release date: | 2008-01-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
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3BOH
 | | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 1 with acetate (CDCA1-R1) | | Descriptor: | ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase | | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | | Deposit date: | 2007-12-17 | | Release date: | 2008-01-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
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2NRF
 | | Crystal Structure of GlpG, a Rhomboid family intramembrane protease | | Descriptor: | Protein GlpG | | Authors: | Wu, Z, Yan, N, Feng, L, Yan, H, Gu, L, Shi, Y. | | Deposit date: | 2006-11-02 | | Release date: | 2006-11-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.
Nat.Struct.Mol.Biol., 13, 2006
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6C5W
 | | Crystal structure of the mitochondrial calcium uniporter | | Descriptor: | CALCIUM ION, calcium uniporter, nanobody | | Authors: | Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. | | Deposit date: | 2018-01-17 | | Release date: | 2018-07-11 | | Last modified: | 2019-04-24 | | Method: | X-RAY DIFFRACTION (3.10010242 Å) | | Cite: | X-ray and cryo-EM structures of the mitochondrial calcium uniporter.
Nature, 559, 2018
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6L62
 | | Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2 Cap protein conformational epitope | | Descriptor: | Capsid protein, Heavy chain of Fab fragment, Light chain of Fab fragment | | Authors: | Sun, Z, Huang, L, Xia, D, Wei, Y, Sun, E, Zhu, H, Bian, H, Wu, H, Feng, L, Wang, J, Liu, C. | | Deposit date: | 2019-10-25 | | Release date: | 2020-02-12 | | Last modified: | 2020-04-29 | | Method: | ELECTRON MICROSCOPY (7.2 Å) | | Cite: | Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope.
J.Virol., 94, 2020
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6LM3
 | | Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2 Cap protein conformational epitope | | Descriptor: | Capsid protein | | Authors: | Sun, Z, Huang, L, Xia, D, Wei, Y, Sun, E, Zhu, H, Bian, H, Wu, H, Feng, L, Wang, J, Liu, C. | | Deposit date: | 2019-12-24 | | Release date: | 2020-02-12 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (6.7 Å) | | Cite: | Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope.
J.Virol., 94, 2020
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3WE5
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8SBB
 | | Cryo-EM structure of FtAlkB | | Descriptor: | Alkane 1-monooxygenase, DODECANE, FE (III) ION, ... | | Authors: | Zhang, J, Feng, L. | | Deposit date: | 2023-04-03 | | Release date: | 2023-04-26 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Structure and mechanism of the alkane-oxidizing enzyme AlkB.
Nat Commun, 14, 2023
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5UHS
 | | Structure of a SemiSWEET D57A mutant | | Descriptor: | MONOVACCENIN, Sugar transporter SemiSWEET, beta-D-glucopyranose | | Authors: | Fastman, N.M, Feng, L. | | Deposit date: | 2017-01-11 | | Release date: | 2017-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Mechanism of Substrate Translocation in an Alternating Access Transporter.
Cell, 169, 2017
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5UHQ
 | | Structure of a SemiSWEET Q20A mutant | | Descriptor: | Sugar transporter SemiSWEET | | Authors: | Fastman, N.M, Feng, L. | | Deposit date: | 2017-01-11 | | Release date: | 2017-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | Mechanism of Substrate Translocation in an Alternating Access Transporter.
Cell, 169, 2017
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