2MD9
| Solution Structure of an Active Site Mutant Pepitdyl Carrier Protein | Descriptor: | Tyrocidine synthase 3 | Authors: | Tufar, P, Rahighi, S, Kraas, F.I, Kirchner, D.K, Loehr, F, Henrich, E, Koepke, J, Dikic, I, Guentert, P, Marahiel, M.A, Doetsch, V. | Deposit date: | 2013-09-06 | Release date: | 2014-04-23 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification. Chem.Biol., 21, 2014
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2O2O
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2KHW
| Solution Structure of the human Polymerase iota UBM2-Ubiquitin Complex | Descriptor: | Immunoglobulin G-binding protein G, DNA polymerase iota, Ubiquitin | Authors: | Bomar, M.G, D'Souza, S, Bienko, M, Dikic, I, Walker, G. | Deposit date: | 2009-04-13 | Release date: | 2010-02-23 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution Structure of the human Polymerase iota UBM2-Ubiquitin Complex To be Published
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3X0W
| Crystal structure of PLEKHM1 LIR-fused human LC3B_2-119 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Suzuki, H, McEwan, D.G, Popovic, D, Gubas, A, Terawaki, S, Stadel, D, Coxon, F, Stegmann, D.M, Bhogaraju, S, Maddi, K, Kirchhoff, A, Gatti, E, Helfrich, M.H, Behrends, C, Pierre, P, Dikic, I, Wakatsuki, S. | Deposit date: | 2014-10-22 | Release date: | 2015-01-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins. Mol.Cell, 57, 2015
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3AXC
| Crystal structure of linear diubiquitin | Descriptor: | GLYCEROL, Ubiquitin | Authors: | Rohaim, A, Kawasaki, M, Kato, R, Dikic, I, Wakatsuki, S. | Deposit date: | 2011-04-01 | Release date: | 2012-01-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structure of a compact conformation of linear diubiquitin Acta Crystallogr.,Sect.D, 68, 2012
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2ZVN
| NEMO CoZi domain incomplex with diubiquitin in P212121 space group | Descriptor: | NF-kappa-B essential modulator, UBC protein | Authors: | Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I. | Deposit date: | 2008-11-12 | Release date: | 2009-03-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation Cell(Cambridge,Mass.), 136, 2009
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2ZVO
| NEMO CoZi domain in complex with diubiquitin in C2 space group | Descriptor: | NF-kappa-B essential modulator, UBC protein | Authors: | Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I. | Deposit date: | 2008-11-12 | Release date: | 2009-03-24 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation Cell(Cambridge,Mass.), 136, 2009
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8OV6
| Ternary structure of intramolecular bivalent glue degrader IBG1 bound to BRD4 and DCAF16:DDB1deltaBPB | Descriptor: | Bromodomain-containing protein 4, DDB1- and CUL4-associated factor 16, DDB1deltaBPB, ... | Authors: | Cowan, A.D, Sundaramoorthy, R, Nakasone, M.A, Ciulli, A. | Deposit date: | 2023-04-25 | Release date: | 2023-05-17 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Targeted protein degradation via intramolecular bivalent glues. Nature, 627, 2024
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4WAA
| Crystal structure of Nix LIR-fused human LC3B_2-119 | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | Authors: | Suzuki, H, Ravichandran, A.C, Dobson, R.C.J, Novak, I, Wakatsuki, S. | Deposit date: | 2014-08-29 | Release date: | 2015-09-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins. Sci Rep, 7, 2017
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6ZQH
| Yeast Uba1 in complex with ubiquitin | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, TETRAETHYLENE GLYCOL, ... | Authors: | Misra, M, Schindelin, H. | Deposit date: | 2020-07-09 | Release date: | 2020-11-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.032 Å) | Cite: | Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection. Chemistry, 27, 2021
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5HKH
| Crystal structure of Ufm1 in complex with UBA5 | Descriptor: | ASP-ASN-GLU-TRP-GLY-ILE-GLU-LEU-VAL, Ubiquitin-fold modifier 1 | Authors: | Huber, J, Doetsch, V, Rogov, V.V, Akutsu, M. | Deposit date: | 2016-01-14 | Release date: | 2016-03-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation. J.Biol.Chem., 291, 2016
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6H8C
| Structure of the human GABARAPL2 protein in complex with the UBA5 LIR motif | Descriptor: | Gamma-aminobutyric acid receptor-associated protein-like 2, Ubiquitin-like modifier-activating enzyme 5 | Authors: | Huber, J, Loehr, F, Gruber, J, Akutsu, M, Guentert, P, Doetsch, V, Rogov, V.V. | Deposit date: | 2018-08-02 | Release date: | 2019-05-01 | Last modified: | 2020-01-29 | Method: | SOLUTION NMR | Cite: | An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5. Autophagy, 16, 2020
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6HB9
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2BZ8
| N-terminal Sh3 domain of CIN85 bound to Cbl-b peptide | Descriptor: | SH3-DOMAIN KINASE BINDING PROTEIN 1, SIGNAL TRANSDUCTION PROTEIN CBL-B SH3-BINDING PROTEIN CBL-B, RING FINGER PROTEIN 56, ... | Authors: | Cardenes, N, Moncalian, G, Bravo, J. | Deposit date: | 2005-08-12 | Release date: | 2005-10-05 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cbl Promotes Clustering of Endocytic Adaptor Proteins Nat.Struct.Mol.Biol., 12, 2005
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4Z4K
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5DPT
| Crystal structure of PLEKHM1 LIR-fused human GABARAPL1_2-117 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Pleckstrin homology domain-containing family M member 1, Gamma-aminobutyric acid receptor-associated protein-like 1,Gamma-aminobutyric acid receptor-associated protein-like 1 | Authors: | Ravichandran, A.C, Suzuki, H, Dobson, R.C.J. | Deposit date: | 2015-09-14 | Release date: | 2016-09-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and functional analysis of the GABARAP interaction motif (GIM). EMBO Rep., 18, 2017
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5DPW
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5DPR
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4Z4M
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5DPS
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6RYA
| Structure of Dup1 mutant H67A:Ubiquitin complex | Descriptor: | Polyubiquitin-C, Septation initiation protein | Authors: | Donghyuk, S, Ivan, D. | Deposit date: | 2019-06-10 | Release date: | 2019-11-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB. Mol.Cell, 77, 2020
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6RYB
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6S5T
| Legionella pneumophila SidJ-Human calmodulin complex | Descriptor: | Calmodulin-2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SidJ | Authors: | Bhogaraju, S, Galej, W.P, Pfleiderer, M.M, Adams, M. | Deposit date: | 2019-07-02 | Release date: | 2019-07-24 | Last modified: | 2019-08-28 | Method: | ELECTRON MICROSCOPY (4.15 Å) | Cite: | Inhibition of bacterial ubiquitin ligases by SidJ-calmodulin catalysed glutamylation. Nature, 572, 2019
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4LJO
| Structure of an active ligase (HOIP)/ubiquitin transfer complex | Descriptor: | E3 ubiquitin-protein ligase RNF31, IMIDAZOLE, Polyubiquitin-C, ... | Authors: | Rana, R.R, Stieglitz, B, Koliopoulos, M.G, Morris-Davies, A.C, Christodoulou, E, Howell, S, Brown, N.R, Rittinger, K. | Deposit date: | 2013-07-05 | Release date: | 2013-10-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.564 Å) | Cite: | Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP. Nature, 503, 2013
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4LJQ
| Crystal structure of the catalytic core of E3 ligase HOIP | Descriptor: | E3 ubiquitin-protein ligase RNF31, ZINC ION | Authors: | Stieglitz, B, Rana, R.R, Koliopoulos, M.G, Morris-Davies, A.C, Christodoulou, E, Howell, S, Brown, N.R, Rittinger, K. | Deposit date: | 2013-07-05 | Release date: | 2013-10-16 | Last modified: | 2013-12-18 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP. Nature, 503, 2013
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