4ZRL
 
 | | Structure of the non canonical Poly(A) polymerase complex GLD-2 - GLD-3 | | Descriptor: | CHLORIDE ION, Defective in germ line development protein 3, Poly(A) RNA polymerase gld-2 | | Authors: | Nakel, K, Bonneau, F, Eckmann, C.R, Conti, E. | | Deposit date: | 2015-05-12 | | Release date: | 2015-07-08 | | Last modified: | 2017-09-06 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Structural basis for the activation of the C. elegans noncanonical cytoplasmic poly(A)-polymerase GLD-2 by GLD-3.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5OOQ
 | | Structure of the Mtr4 Nop53 Complex | | Descriptor: | ATP-dependent RNA helicase DOB1, Ribosome biogenesis protein NOP53, SULFATE ION | | Authors: | Falk, S, Basquin, J, Conti, E. | | Deposit date: | 2017-08-08 | | Release date: | 2017-09-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53.
RNA, 23, 2017
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4BA2
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4BA1
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2HWX
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2HWW
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2HWY
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2J0U
 | | The crystal structure of eIF4AIII-Barentsz complex at 3.0 A resolution | | Descriptor: | ATP-DEPENDENT RNA HELICASE DDX48, PROTEIN CASC3 | | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | | Deposit date: | 2006-08-04 | | Release date: | 2006-09-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna
Cell(Cambridge,Mass.), 126, 2006
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2J0S
 | | The crystal structure of the Exon Junction Complex at 2.2 A resolution | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP *UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ... | | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | | Deposit date: | 2006-08-04 | | Release date: | 2006-09-06 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna
Cell(Cambridge,Mass.), 126, 2006
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2J0Q
 | | The crystal structure of the Exon Junction Complex at 3.2 A resolution | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ... | | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | | Deposit date: | 2006-08-04 | | Release date: | 2006-08-30 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on Mrna.
Cell(Cambridge,Mass.), 126, 2006
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7PW4
 | | Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor | | Descriptor: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Langer, L.M, Conti, E. | | Deposit date: | 2021-10-06 | | Release date: | 2021-12-01 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
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7PW8
 | | Human SMG1-8-9 kinase complex bound to AMPPNP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Langer, L.M, Conti, E. | | Deposit date: | 2021-10-06 | | Release date: | 2021-12-01 | | Method: | ELECTRON MICROSCOPY (2.82 Å) | | Cite: | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
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7PW6
 | | Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor - SMG1 body | | Descriptor: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, INOSITOL HEXAKISPHOSPHATE, Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1 | | Authors: | Langer, L.M, Conti, E. | | Deposit date: | 2021-10-06 | | Release date: | 2021-12-01 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
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7PW9
 | | Human SMG1-9 kinase complex bound to AMPPNP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Langer, L.M, Conti, E. | | Deposit date: | 2021-10-06 | | Release date: | 2021-12-01 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
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7PW7
 | | Human SMG1-9 kinase complex bound to a SMG1 inhibitor | | Descriptor: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Langer, L.M, Conti, E. | | Deposit date: | 2021-10-06 | | Release date: | 2021-12-01 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Elife, 10, 2021
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7PW5
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2JEA
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2JEB
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2JE6
 | | Structure of a 9-subunit archaeal exosome | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, EXOSOME COMPLEX EXONUCLEASE 1, ... | | Authors: | Lorentzen, E, Conti, E. | | Deposit date: | 2007-01-15 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | RNA Channelling by the Archaeal Exosome.
Embo Rep., 8, 2007
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2JA9
 | | Structure of the N-terminal deletion of yeast exosome component Rrp40 | | Descriptor: | EXOSOME COMPLEX EXONUCLEASE RRP40 | | Authors: | Oddone, A, Lorentzen, E, Basquin, J, Gasch, A, Rybin, V, Conti, E, Sattler, M. | | Deposit date: | 2006-11-24 | | Release date: | 2006-12-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and Biochemical Characterization of the Yeast Exosome Component Rrp40
Embo Rep., 8, 2007
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5AJD
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5AIE
 | | Not4 ring domain in complex with Ubc4 | | Descriptor: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 4, UBIQUITIN-CONJUGATING ENZYME E2 4, ZINC ION | | Authors: | Bhaskar, V, Basquin, J, Conti, E. | | Deposit date: | 2015-02-12 | | Release date: | 2015-04-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Architecture of the Ubiquitylation Module of the Yeast Ccr4-not Complex.
Structure, 23, 2015
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5ANR
 | | Structure of a human 4E-T - DDX6 - CNOT1 complex | | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | | Authors: | Basquin, J, Oezguer, S, Conti, E. | | Deposit date: | 2015-09-08 | | Release date: | 2015-10-21 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Structure of a Human 4E-T/Ddx6/Cnot1 Complex Reveals the Different Interplay of Ddx6-Binding Proteins with the Ccr4-not Complex.
Cell Rep., 13, 2015
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5AOR
 | | Structure of MLE RNA ADP AlF4 complex | | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, DOSAGE COMPENSATION REGULATOR, ... | | Authors: | Prabu, J.R, Conti, E. | | Deposit date: | 2015-09-11 | | Release date: | 2015-11-18 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structure of the RNA Helicase Mle Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling.
Mol.Cell, 60, 2015
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5NKK
 | | SMG8-SMG9 complex GDP bound | | Descriptor: | 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Li, L, Basquin, J, Conti, E. | | Deposit date: | 2017-03-31 | | Release date: | 2017-04-19 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
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