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8F2R
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BU of 8f2r by Molmil
Human CCC complex
Descriptor: COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ...
Authors:Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J.
Deposit date:2022-11-08
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
6XS7
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BU of 6xs7 by Molmil
Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-D2
Descriptor: 48V-DTY-THR-THR-ILE-TYR-TRP-THR-PRO-LEU-GLY-THR-PHE-PRO-ARG-ILE-ARG, FORMIC ACID, GLYCEROL, ...
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2020-07-15
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XSA
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BU of 6xsa by Molmil
Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-L2
Descriptor: 48V-TYR-LEU-PRO-THR-ILE-THR-GLY-VAL-GLY-HIS-LEU-TRP-HIS-PRO-LEU, SULFATE ION, Vacuolar protein sorting-associated protein 29
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2020-07-15
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XS5
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BU of 6xs5 by Molmil
Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-D1
Descriptor: 48V-DTY-ILE-ILE-ASP-THR-PRO-LEU-GLY-VAL-PHE-LEU-SER-SER-LEU-LYS-ARG, FORMIC ACID, GLYCEROL, ...
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2020-07-15
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XS9
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BU of 6xs9 by Molmil
Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-L1
Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 48V-TYR-ILE-LYS-THR-PRO-LEU-GLY-THR-PHE-PRO-ASN-ARG-HIS-GLY, GLYCEROL, ...
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2020-07-15
Release date:2021-07-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XS8
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BU of 6xs8 by Molmil
Crystal structure of Chaetomium thermophilum Vps29 complexed with RaPID-derived cyclic peptide RT-D3
Descriptor: 48V-DTY-GLY-TYR-ASP-PRO-LEU-GLY-LEU-LYS-TYR-PHE-ALA, Vacuolar protein sorting-associated protein 29
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2020-07-15
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95009851 Å)
Cite:De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
8ESD
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BU of 8esd by Molmil
Crystal structure of COMMD7-COMMD9-COMMD5-COMMD10 tetramer
Descriptor: COMM domain-containing protein 10, COMM domain-containing protein 5, COMM domain-containing protein 7, ...
Authors:Healy, M.D, Collins, B.M.
Deposit date:2022-10-13
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
8ESE
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BU of 8ese by Molmil
Crystal structure of human Vps29 bound to a peptide from Vps35L
Descriptor: VPS35 endosomal protein-sorting factor-like, Vacuolar protein sorting-associated protein 29
Authors:Healy, M.D, Collins, B.M.
Deposit date:2022-10-13
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
8ESF
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BU of 8esf by Molmil
Crystal structure of human Nischarin PX and LRR domains with engineered mutations
Descriptor: IMIDAZOLE, Nischarin
Authors:Eldershaw, D.E, Collins, B.M.
Deposit date:2022-10-13
Release date:2023-10-25
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Crystal structure of human Nischarin PX and LRR domains with engineered mutations
To Be Published
5WOE
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BU of 5woe by Molmil
Solution structure of the sorting nexin 25 phox-homology domain
Descriptor: Sorting nexin-25
Authors:Chin, Y.K.Y, Mas, C, Mobli, M, Collins, B.M.
Deposit date:2017-08-01
Release date:2018-08-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
6BTY
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BU of 6bty by Molmil
Crystal structure of the PI3KC2alpha C2 domain in space group P41212
Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
Authors:Chen, K.-E, Collins, B.M.
Deposit date:2017-12-08
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.678 Å)
Cite:Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
6BTZ
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BU of 6btz by Molmil
Crystal structure of the PI3KC2alpha C2 domain in space group C121
Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, ...
Authors:Chen, K.-E, Collins, B.M.
Deposit date:2017-12-08
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
6BP6
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BU of 6bp6 by Molmil
Crystal structure of Commd9 COMM domain
Descriptor: COMM domain-containing protein 9
Authors:Healy, M.D, Chandra, M, Collins, B.M, Ghai, R.
Deposit date:2017-11-22
Release date:2018-08-15
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural insights into the architecture and membrane interactions of the conserved COMMD proteins.
Elife, 7, 2018
6BU0
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BU of 6bu0 by Molmil
Crystal structure of the PI3KC2alpha C2 domain in complex with IP6
Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Chen, K.-E, Collins, B.M.
Deposit date:2017-12-08
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.427 Å)
Cite:Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
6BUB
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BU of 6bub by Molmil
Crystal structure of the PI3KC2alpha PX domain in space group P432
Descriptor: GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, SULFATE ION
Authors:Chen, K.-E, Collins, B.M.
Deposit date:2017-12-09
Release date:2018-10-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
7RM8
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BU of 7rm8 by Molmil
Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide
Descriptor: Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion
Authors:Healy, M.D, Collins, B.M, Mobli, M.
Deposit date:2021-07-26
Release date:2022-08-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins.
Structure, 30, 2022
4QKV
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BU of 4qkv by Molmil
Crystal structure of the mouse cavin1 HR1 domain
Descriptor: Polymerase I and transcript release factor
Authors:Kovtun, O, Tillu, V, Parton, R.G, Collins, B.M.
Deposit date:2014-06-10
Release date:2015-03-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into the organization of the cavin membrane coat complex
Dev.Cell, 31, 2014
4QKW
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BU of 4qkw by Molmil
Crystal structure of the zebrafish cavin4a HR1 domain
Descriptor: CHLORIDE ION, Muscle-related coiled-coil protein
Authors:Kovtun, O, Tillu, V, Parton, R.G, Collins, B.M.
Deposit date:2014-06-10
Release date:2015-03-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the organization of the cavin membrane coat complex
Dev.Cell, 31, 2014
1NA8
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BU of 1na8 by Molmil
Crystal structure of ADP-ribosylation factor binding protein GGA1
Descriptor: ADP-ribosylation factor binding protein GGA1
Authors:Lui, W.W, Collins, B.M, Hirst, J, Motley, A, Millar, C, Schu, P, Owen, D.J, Robinson, M.S.
Deposit date:2002-11-27
Release date:2003-07-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin
Mol.Cell.Biol., 14, 2003
4GXB
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BU of 4gxb by Molmil
Structure of the SNX17 atypical FERM domain bound to the NPxY motif of P-selectin
Descriptor: GLYCEROL, P-selectin, Sorting nexin-17
Authors:Ghai, R, Bugarcic, A, Liu, H, Norwood, S.J, Li, S.S, Teasdale, R.D, Collins, B.M.
Deposit date:2012-09-04
Release date:2013-03-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
6EDX
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BU of 6edx by Molmil
Crystal Structure of SGK3 PX domain
Descriptor: GLYCEROL, Serine/threonine-protein kinase Sgk3
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-12
Release date:2018-09-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
6EE0
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BU of 6ee0 by Molmil
Crystal Structure of SNX23 PX domain
Descriptor: Kinesin-like protein KIF16B
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-12
Release date:2018-08-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.518 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
6ECM
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BU of 6ecm by Molmil
Crystal Structure of SNX15 PX domain in domain swapped conformation
Descriptor: SULFATE ION, Sorting nexin-15
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-08
Release date:2018-08-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.353 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
1R4X
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BU of 1r4x by Molmil
Crystal Structure Analys of the Gamma-COPI Appendage domain
Descriptor: Coatomer gamma subunit, MAGNESIUM ION
Authors:Watson, P.J, Frigerio, G, Collins, B.M, Duden, R, Owen, D.J.
Deposit date:2003-10-09
Release date:2003-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Gamma-COP appendage domain - structure and function
Traffic, 5, 2004
2G30
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BU of 2g30 by Molmil
beta appendage of AP2 complexed with ARH peptide
Descriptor: 16-mer peptide from Low density lipoprotein receptor adapter protein 1, AP-2 complex subunit beta-1, peptide sequence AAF
Authors:Edeling, M.A, Collins, B.M, Traub, L.M, Owen, D.J.
Deposit date:2006-02-17
Release date:2006-03-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular Switches Involving the AP-2 beta2 Appendage Regulate Endocytic Cargo Selection and Clathrin Coat Assembly
Dev.Cell, 10, 2006

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