4V32
 
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Y101F mutant | | Descriptor: | CEREBLON ISOFORM 4, S-Thalidomide, ZINC ION | | Authors: | Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B. | | Deposit date: | 2014-10-15 | | Release date: | 2014-12-17 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon.
J.Struct.Biol., 188, 2014
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5FZS
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6H9M
 | | Coiled-coil domain-containing protein 90B residues 43-125 from Homo sapiens fused to a GCN4 adaptor | | Descriptor: | Coiled-coil domain-containing protein 90B, mitochondrial,General control protein GCN4 | | Authors: | Adlakha, J, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D. | | Deposit date: | 2018-08-04 | | Release date: | 2019-02-13 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Characterization of MCU-Binding Proteins MCUR1 and CCDC90B - Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles.
Structure, 27, 2019
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6H9L
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8A92
 | | p53-Y220C Core Domain in Complex with a Bromo-trifluoro-pyrazole-amine | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-bromanyl-5-(trifluoromethyl)-1H-pyrazol-3-amine, Cellular tumor antigen p53, ... | | Authors: | Stahlecker, J, Braun, M.B, Stehle, T, Boeckler, F.M. | | Deposit date: | 2022-06-27 | | Release date: | 2022-11-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C.
Rsc Med Chem, 13, 2022
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7ZH8
 | | DYRK1a in Complex with a Bromo-Triazolo-Pyridine | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-bromanyl-3H-[1,2,3]triazolo[4,5-b]pyridine, CHLORIDE ION, ... | | Authors: | Dammann, M, Stahlecker, J, Stehle, T, Boeckler, F.M. | | Deposit date: | 2022-04-05 | | Release date: | 2022-11-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes.
J.Med.Chem., 65, 2022
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5A1Q
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3ZRW
 | | The structure of the dimeric Hamp-Dhp fusion A291V mutant | | Descriptor: | AF1503 PROTEIN, OSMOLARITY SENSOR PROTEIN ENVZ | | Authors: | Zeth, K, Hulko, M, Ferris, H.U, Martin, J, Lupas, A.N. | | Deposit date: | 2011-06-20 | | Release date: | 2011-06-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Mechanism of Regulation of Receptor Histidine Kinases.
Structure, 20, 2012
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3ZRV
 | | The high resolution structure of a dimeric Hamp-Dhp fusion displays asymmetry - A291F mutant | | Descriptor: | HAMP, OSMOLARITY SENSOR PROTEIN ENVZ | | Authors: | Zeth, K, Hulko, M, Ferris, H.U, Martin, J. | | Deposit date: | 2011-06-20 | | Release date: | 2011-07-06 | | Last modified: | 2017-03-15 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Mechanism of Regulation of Receptor Histidine Kinases.
Structure, 20, 2012
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4V2Y
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3ZRX
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5FZQ
 | | Designed TPR Protein M4N | | Descriptor: | DESIGNED TPR PROTEIN, SULFATE ION | | Authors: | Albrecht, R, Zhu, H, Hartmann, M.D. | | Deposit date: | 2016-03-15 | | Release date: | 2016-10-12 | | Last modified: | 2017-03-15 | | Method: | X-RAY DIFFRACTION (2.148 Å) | | Cite: | Origin of a folded repeat protein from an intrinsically disordered ancestor.
Elife, 5, 2016
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5FZR
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2VBU
 | | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Hartmann, M.D, Ammelburg, M, Djuranovic, S, Martin, J, Lupas, A.N, Zeth, K. | | Deposit date: | 2007-09-16 | | Release date: | 2007-11-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels.
Structure, 15, 2007
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2VBS
 | | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with PO4 | | Descriptor: | CHLORIDE ION, PHOSPHATE ION, RIBOFLAVIN KINASE, ... | | Authors: | Hartmann, M.D, Djuranovic, S, Ammelburg, M, Martin, J, Lupas, A.N, Zeth, K. | | Deposit date: | 2007-09-16 | | Release date: | 2007-11-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels.
Structure, 15, 2007
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2VBV
 | | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP and FMN | | Descriptor: | CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Hartmann, M.D, Ammelburg, M, Djuranovic, S, Martin, J, Lupas, A.N, Zeth, K. | | Deposit date: | 2007-09-16 | | Release date: | 2007-11-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels.
Structure, 15, 2007
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2VBT
 | | Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP and PO4 | | Descriptor: | CYTIDINE-5'-DIPHOSPHATE, PHOSPHATE ION, RIBOFLAVIN KINASE, ... | | Authors: | Hartmann, M.D, Ammelburg, M, Djuranovic, S, Martin, J, Lupas, A.N, Zeth, K. | | Deposit date: | 2007-09-16 | | Release date: | 2007-11-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels.
Structure, 15, 2007
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2Y21
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2Y0T
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2Y20
 | | The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291I mutant | | Descriptor: | UNCHARACTERIZED PROTEIN, ZINC ION | | Authors: | Zeth, K, Ferris, H.U, Hulko, M, Lupas, A.N. | | Deposit date: | 2010-12-12 | | Release date: | 2011-07-20 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The Mechanisms of Hamp-Mediated Signaling in Transmembrane Receptors.
Structure, 19, 2011
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2Y0Q
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5AMK
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in multiple conformations, hexagonal crystal form | | Descriptor: | CEREBLON ISOFORM 4, DIMETHYL SULFOXIDE, S-Thalidomide, ... | | Authors: | Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B. | | Deposit date: | 2015-03-10 | | Release date: | 2015-07-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural Dynamics of the Cereblon Ligand Binding Domain.
Plos One, 10, 2015
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5AMH
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, trigonal crystal form | | Descriptor: | CALCIUM ION, CEREBLON ISOFORM 4, CHLORIDE ION, ... | | Authors: | Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B. | | Deposit date: | 2015-03-10 | | Release date: | 2015-07-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structural Dynamics of the Cereblon Ligand Binding Domain.
Plos One, 10, 2015
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5AMI
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Wash I structure | | Descriptor: | CEREBLON ISOFORM 4, S-Thalidomide, ZINC ION | | Authors: | Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B. | | Deposit date: | 2015-03-10 | | Release date: | 2015-07-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural Dynamics of the Cereblon Ligand Binding Domain.
Plos One, 10, 2015
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5AMJ
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Thalidomide, Wash II structure | | Descriptor: | CEREBLON ISOFORM 4, PHOSPHATE ION, S-Thalidomide, ... | | Authors: | Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B. | | Deposit date: | 2015-03-10 | | Release date: | 2015-07-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural Dynamics of the Cereblon Ligand Binding Domain.
Plos One, 10, 2015
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