5IM6
| Crystal structure of designed two-component self-assembling icosahedral cage I32-28 | 分子名称: | Designed self-assembling icosahedral cage I32-28 dimeric subunit, Designed self-assembling icosahedral cage I32-28 trimeric subunit | 著者 | Liu, Y.A, Cascio, D, Sawaya, M.R, Bale, J.B, Collazo, M.J, Thomas, C, Sheffler, W, King, N.P, Baker, D, Yeates, T.O. | 登録日 | 2016-03-05 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (5.588 Å) | 主引用文献 | Accurate design of megadalton-scale two-component icosahedral protein complexes. Science, 353, 2016
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5IM4
| Crystal structure of designed two-component self-assembling icosahedral cage I52-32 | 分子名称: | 6,7-dimethyl-8-ribityllumazine synthase, Phosphotransferase system, mannose/fructose-specific component IIA | 著者 | Liu, Y.A, Cascio, D, Sawaya, M.R, Bale, J.B, Collazo, M.J, Thomas, C, Sheffler, W, King, N.P, Baker, D, Yeates, T.O. | 登録日 | 2016-03-05 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Accurate design of megadalton-scale two-component icosahedral protein complexes. Science, 353, 2016
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7LUZ
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7LV2
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7MPK
| Crystal structure of TagA with UDP-GlcNAc | 分子名称: | N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | 著者 | Martinez, O.E, Cascio, D, Clubb, R.T. | 登録日 | 2021-05-04 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.993 Å) | 主引用文献 | Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA. J.Biol.Chem., 298, 2021
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1F1E
| CRYSTAL STRUCTURE OF THE HISTONE FROM METHANOPYRUS KANDLERI | 分子名称: | CHLORIDE ION, HISTONE FOLD PROTEIN | 著者 | Fahrner, R.L, Cascio, D, Lake, J.A, Slesarev, A. | 登録日 | 2000-05-18 | 公開日 | 2001-10-31 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | An ancestral nuclear protein assembly: crystal structure of the Methanopyrus kandleri histone. Protein Sci., 10, 2001
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5HS0
| Computationally Designed Cyclic Tetramer ank1C4_7 | 分子名称: | Ankyrin domain protein ank1C4_7, GLYCEROL, SULFATE ION | 著者 | McNamara, D.E, Cascio, D, Fallas, J.A, Baker, D, Yeates, T.O. | 登録日 | 2016-01-24 | 公開日 | 2017-04-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem, 9, 2017
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1YAC
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1ZR0
| Crystal Structure of Kunitz Domain 1 of Tissue Factor Pathway Inhibitor-2 with Bovine Trypsin | 分子名称: | CALCIUM ION, Cationic trypsin, Tissue factor pathway inhibitor 2 | 著者 | Schmidt, A.E, Chand, H.S, Cascio, D, Kisiel, W, Bajaj, S.P. | 登録日 | 2005-05-18 | 公開日 | 2005-06-07 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition J.Biol.Chem., 280, 2005
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274D
| CRYSTAL STRUCTURE OF A COVALENT DNA-DRUG ADDUCT: ANTHRAMYCIN BOUND TO C-C-A-A-C-G-T-T-G-G, AND A MOLECULAR EXPLANATION OF SPECIFICITY | 分子名称: | ANTHRAMYCIN, DNA (5'-D(*CP*CP*AP*AP*CP*GP*TP*TP*(DRUG)GP*G)-3') | 著者 | Kopka, M.L, Goodsell, D.S, Baikalov, I, Grzeskowiak, K, Cascio, D, Dickerson, R.E. | 登録日 | 1994-04-28 | 公開日 | 1994-10-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a covalent DNA-drug adduct: anthramycin bound to C-C-A-A-C-G-T-T-G-G and a molecular explanation of specificity. Biochemistry, 33, 1994
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5K7P
| MicroED structure of xylanase at 2.3 A resolution | 分子名称: | Endo-1,4-beta-xylanase 2, IODIDE ION | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.3 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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6O4J
| Amyloid Beta KLVFFAENVGS 16-26 D23N Iowa mutation | 分子名称: | Amyloid-beta precursor protein | 著者 | Griner, S.L, Sawaya, M.R, Rodriguez, J.A, Cascio, D, Gonen, T. | 登録日 | 2019-02-28 | 公開日 | 2019-10-30 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.402 Å) | 主引用文献 | Structure based inhibitors of Amyloid Beta core suggest a common interface with Tau. Elife, 8, 2019
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5K7R
| MicroED structure of trypsin at 1.7 A resolution | 分子名称: | CALCIUM ION, Cationic trypsin | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2018-08-22 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.7 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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5K7Q
| MicroED structure of thaumatin at 2.5 A resolution | 分子名称: | Thaumatin-1 | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2018-08-22 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.5 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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5K7O
| MicroED structure of lysozyme at 1.8 A resolution | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2018-08-22 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.8 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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5K7T
| MicroED structure of thermolysin at 2.5 A resolution | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ... | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.5 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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5K7N
| MicroED structure of tau VQIVYK peptide at 1.1 A resolution | 分子名称: | VQIVYK | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.1 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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5K7S
| MicroED structure of proteinase K at 1.6 A resolution | 分子名称: | CALCIUM ION, Proteinase K | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2018-08-22 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.6 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
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6P0T
| Crystal structure of ternary DNA complex "FX(1-2)-1Xis" containing E. coli Fis and phage lambda Xis | 分子名称: | DNA (27-MER), FX1-2, DNA-binding protein Fis, ... | 著者 | Hancock, S.P, Cascio, D, Johnson, R.C. | 登録日 | 2019-05-17 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.603 Å) | 主引用文献 | Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res., 47, 2019
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2OG0
| Crystal Structure of the Lambda Xis-DNA complex | 分子名称: | 5'-D(*AP*AP*AP*CP*AP*GP*AP*CP*TP*AP*CP*AP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*TP*AP*TP*TP*AP*TP*GP*TP*AP*GP*TP*CP*TP*GP*TP*TP*T)-3', Excisionase | 著者 | Papagiannis, C.V, Sam, M.D, Abbani, M.A, Cascio, D, Yoo, D, Clubb, R.T, Johnson, R.C. | 登録日 | 2007-01-04 | 公開日 | 2007-03-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Fis targets assembly of the xis nucleoprotein filament to promote excisive recombination by phage lambda. J.Mol.Biol., 367, 2007
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1L9L
| GRANULYSIN FROM HUMAN CYTOLYTIC T LYMPHOCYTES | 分子名称: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ETHANOL, Granulysin, ... | 著者 | Anderson, D.H, Sawaya, M.R, Cascio, D, Ernst, W, Krensky, A, Modlin, R, Eisenberg, D. | 登録日 | 2002-03-25 | 公開日 | 2002-11-06 | 最終更新日 | 2017-09-13 | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | 主引用文献 | Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism J.Mol.Biol., 325, 2002
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1LMI
| 1.5 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS-MPT63 | 分子名称: | Immunogenic protein MPT63/MPB63 | 著者 | Goulding, C.W, Parseghian, A, Sawaya, M.R, Cascio, D, Apostol, M, Gennaro, M.L, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2002-05-01 | 公開日 | 2002-12-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at
1.5-A resolution Protein Sci., 11, 2002
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307D
| Structure of a DNA analog of the primer for HIV-1 RT second strand synthesis | 分子名称: | DNA (5'-D(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*TP*TP*CP*TP*TP*TP*G)-3') | 著者 | Han, G.W, Kopka, M.L, Cascio, D, Grzeskowiak, K, Dickerson, R.E. | 登録日 | 1997-01-07 | 公開日 | 1997-01-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of a DNA analog of the primer for HIV-1 RT second strand synthesis. J.Mol.Biol., 269, 1997
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3DH4
| Crystal Structure of Sodium/Sugar symporter with bound Galactose from vibrio parahaemolyticus | 分子名称: | ERBIUM (III) ION, SODIUM ION, Sodium/glucose cotransporter, ... | 著者 | Abramson, J, Faham, S, Cascio, D. | 登録日 | 2008-06-16 | 公開日 | 2008-08-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport. Science, 321, 2008
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5KO0
| Human Islet Amyloid Polypeptide Segment 15-FLVHSSNNFGA-25 Determined by MicroED | 分子名称: | THIOCYANATE ION, hIAPP(15-25)WT | 著者 | Krotee, P.A.L, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Shi, D, Nannenga, B.L, Hattne, J, Reyes, F.E, Gonen, T, Eisenberg, D.S. | 登録日 | 2016-06-28 | 公開日 | 2016-12-21 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.4 Å) | 主引用文献 | Atomic structures of fibrillar segments of hIAPP suggest tightly mated beta-sheets are important for cytotoxicity. Elife, 6, 2017
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