7OC5
| Alpha-humulene synthase AsR6 from Sarocladium schorii | 分子名称: | Alpha-humulene synthase AsR6, MAGNESIUM ION, ZINC ION | 著者 | Schotte, C, Lukat, P, Deuschmann, A, Blankenfeldt, W, Cox, R.J. | 登録日 | 2021-04-26 | 公開日 | 2021-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Understanding and Engineering the Stereoselectivity of Humulene Synthase. Angew.Chem.Int.Ed.Engl., 60, 2021
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7OZQ
| Crystal structure of archaeal L7Ae bound to eukaryotic kink-loop | 分子名称: | 50S ribosomal protein L7Ae, ACETATE ION, CALCIUM ION, ... | 著者 | Hoefler, S, Lukat, P, Carlomagno, T, Blankenfeldt, W. | 登録日 | 2021-06-28 | 公開日 | 2021-10-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Eukaryotic Box C/D methylation machinery has two non-symmetric protein assembly sites. Sci Rep, 11, 2021
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3ZHH
| X-ray structure of the full-length beta-lactamase from M.tuberculosis | 分子名称: | BETA-LACTAMASE, SULFATE ION | 著者 | Feiler, C, Fisher, A.C, Marrichi, M.J, Wright, L, Schmidpeter, P.A.M, Blankenfeldt, W, Pavelka, M, DeLisa, M.P. | 登録日 | 2012-12-21 | 公開日 | 2013-09-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Directed Evolution of Mycobacterium Tuberculosis Beta-Lactamase Reveals Gatekeeper Residue that Regulates Antibiotic Resistance and Catalytic Efficiency. Plos One, 8, 2013
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6YA1
| Zinc metalloprotease ProA | 分子名称: | ACETATE ION, CALCIUM ION, ZINC ION, ... | 著者 | Schmelz, S, Blankenfeldt, W. | 登録日 | 2020-03-11 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation. Cell.Microbiol., 23, 2021
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3B4O
| Crystal structure of phenazine biosynthesis protein PhzA/B from Burkholderia cepacia R18194, apo form | 分子名称: | ACETATE ION, Phenazine biosynthesis protein A/B | 著者 | Ahuja, E.G, Janning, P, Mentel, M, Graebsch, A, Breinbauer, R, Blankenfeldt, W. | 登録日 | 2007-10-24 | 公開日 | 2008-12-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | PhzA/B catalyzes the formation of the tricycle in phenazine biosynthesis. J.Am.Chem.Soc., 130, 2008
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6RTD
| Dihydro-heme d1 dehydrogenase NirN in complex with DHE | 分子名称: | (R,R)-2,3-BUTANEDIOL, Cytochrome c, HEME C, ... | 著者 | Kluenemann, T, Preuss, A, Layer, G, Blankenfeldt, W. | 登録日 | 2019-05-23 | 公開日 | 2019-06-19 | 最終更新日 | 2019-08-28 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Crystal Structure of Dihydro-Heme d1Dehydrogenase NirN from Pseudomonas aeruginosa Reveals Amino Acid Residues Essential for Catalysis. J.Mol.Biol., 431, 2019
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3B4P
| Crystal structure of phenazine biosynthesis protein PhzA/B from Burkholderia cepacia R18194, complex with 2-(cyclohexylamino)benzoic acid | 分子名称: | 2-(cyclohexylamino)benzoic acid, ACETATE ION, AZIDE ION, ... | 著者 | Ahuja, E.G, Janning, P, Mentel, M, Graebsch, A, Breinbauer, R, Blankenfeldt, W. | 登録日 | 2007-10-24 | 公開日 | 2008-12-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | PhzA/B catalyzes the formation of the tricycle in phenazine biosynthesis. J.Am.Chem.Soc., 130, 2008
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4AY8
| SeMet-derivative of a methyltransferase from M. mazei | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1-THIOETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Hoeppner, A, Thomas, F, Rueppel, A, Hensel, R, Blankenfeldt, W, Bayer, P, Faust, A. | 登録日 | 2012-06-18 | 公開日 | 2012-10-31 | 最終更新日 | 2014-11-05 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the Corrinoid:Coenzyme M Methyltransferase Mtaa from Methanosarcina Mazei Acta Crystallogr.,Sect.D, 68, 2012
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3CNM
| Crystal Structure of Phenazine Biosynthesis Protein PhzA/B from Burkholderia cepacia R18194, DHHA complex | 分子名称: | (2S,3S)-TRANS-2,3-DIHYDRO-3-HYDROXYANTHRANILIC ACID, ACETATE ION, Phenazine biosynthesis protein A/B | 著者 | Ahuja, E.G, Blankenfeldt, W. | 登録日 | 2008-03-26 | 公開日 | 2008-12-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | PhzA/B catalyzes the formation of the tricycle in phenazine biosynthesis. J.Am.Chem.Soc., 130, 2008
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7QY3
| Crystal structure of the halohydrin dehalogenase HheG D114C mutant cross-linked with BMOE | 分子名称: | 1,1'-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), Putative oxidoreductase, SULFATE ION | 著者 | Henke, S, Blankenfeldt, W, Schallmey, A. | 登録日 | 2022-01-27 | 公開日 | 2022-03-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Biocatalytically active and stable cross-linked enzyme crystals of halohydrin dehalogenase HheG by protein engineering Chemcatchem, 2022
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7R3E
| Fusion construct of PqsE and RhlR in complex with the synthetic antagonist mBTL | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase,Regulatory protein RhlR, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, FE (III) ION | 著者 | Borgert, S.R, Schmelz, S, Blankenfeldt, W. | 登録日 | 2022-02-07 | 公開日 | 2022-12-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | 主引用文献 | Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
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7R3J
| Nativ complex of PqsE and RhlR with the synthetic antagonist mBTL | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, 4-(3-bromophenoxy)-N-[(3S)-2-oxothiolan-3-yl]butanamide, FE (III) ION, ... | 著者 | Borgert, S.R, Schmelz, S, Blankenfeldt, W. | 登録日 | 2022-02-07 | 公開日 | 2022-12-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
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7R3I
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7R3F
| Monomeric PqsE mutant E187R | 分子名称: | 2-aminobenzoylacetyl-CoA thioesterase, BENZOIC ACID, CACODYLATE ION, ... | 著者 | Borgert, S.R, Schmelz, S, Blankenfeldt, W. | 登録日 | 2022-02-07 | 公開日 | 2022-12-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa. Nat Commun, 13, 2022
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7R3G
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7R3H
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4X8D
| Ergothioneine-biosynthetic sulfoxide synthase EgtB in complex with N,N-dimethyl-histidine and gamma-glutamyl-cysteine | 分子名称: | CALCIUM ION, CHLORIDE ION, GAMMA-GLUTAMYLCYSTEINE, ... | 著者 | Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P. | 登録日 | 2014-12-10 | 公開日 | 2015-01-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angew.Chem.Int.Ed.Engl., 54, 2015
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4X8B
| Ergothioneine-biosynthetic sulfoxide synthase EgtB, apo form | 分子名称: | CALCIUM ION, CHLORIDE ION, FE (III) ION, ... | 著者 | Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P. | 登録日 | 2014-12-10 | 公開日 | 2015-01-28 | 最終更新日 | 2017-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angew.Chem.Int.Ed.Engl., 54, 2015
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4X8E
| Ergothioneine-biosynthetic sulfoxide synthase EgtB in complex with N,N,N-trimethyl-histidine | 分子名称: | CALCIUM ION, CHLORIDE ION, FE (III) ION, ... | 著者 | Vit, A, Goncharenko, K.V, Blankenfeldt, W, Seebeck, F.P. | 登録日 | 2014-12-10 | 公開日 | 2015-01-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angew.Chem.Int.Ed.Engl., 54, 2015
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4ZFL
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4ZFK
| Ergothioneine-biosynthetic Ntn hydrolase EgtC with glutamine | 分子名称: | 1,2-ETHANEDIOL, Amidohydrolase EgtC, GLUTAMINE | 著者 | Vit, A, Seebeck, F.P, Blankenfeldt, W. | 登録日 | 2015-04-21 | 公開日 | 2015-07-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC. Chembiochem, 16, 2015
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4ZFJ
| Ergothioneine-biosynthetic Ntn hydrolase EgtC, apo form | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Amidohydrolase EgtC | 著者 | Vit, A, Seebeck, F.P, Blankenfeldt, W. | 登録日 | 2015-04-21 | 公開日 | 2015-07-01 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC. Chembiochem, 16, 2015
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5MZZ
| Crystal structure of the decarboxylase AibA/AibB in complex with 3-methylglutaconate | 分子名称: | 3-methylpent-2-enedioic acid, ACETATE ION, GLYCEROL, ... | 著者 | Bock, T, Luxenburger, E, Hoffmann, J, Schuetza, V, Feiler, C, Mueller, R, Blankenfeldt, W. | 登録日 | 2017-02-02 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | AibA/AibB Induces an Intramolecular Decarboxylation in Isovalerate Biosynthesis by Myxococcus xanthus. Angew. Chem. Int. Ed. Engl., 56, 2017
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3JUN
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5NCI
| GriE in complex with cobalt, alpha-ketoglutarate and l-leucine | 分子名称: | 2-OXOGLUTARIC ACID, COBALT (II) ION, LEUCINE, ... | 著者 | Lukat, P, Blankenfeldt, W, Mueller, R. | 登録日 | 2017-03-05 | 公開日 | 2017-10-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.755 Å) | 主引用文献 | Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity. Chem Sci, 8, 2017
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