9BUN
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3LQX
| SRP ribonucleoprotein core complexed with cobalt hexammine | Descriptor: | CHLORIDE ION, COBALT HEXAMMINE(III), POTASSIUM ION, ... | Authors: | Batey, R.T. | Deposit date: | 2010-02-10 | Release date: | 2010-03-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural and Energetic Analysis of Metal Ions Essential to SRP Signal Recognition Domain Assembly Biochemistry, 41, 2002
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1DUL
| STRUCTURE OF THE RIBONUCLEOPROTEIN CORE OF THE E. COLI SIGNAL RECOGNITION PARTICLE | Descriptor: | 4.5 S RNA DOMAIN IV, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Batey, R.T, Rambo, R.P, Lucast, L, Rha, B, Doudna, J.A. | Deposit date: | 2000-01-17 | Release date: | 2000-02-28 | Last modified: | 2020-10-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the ribonucleoprotein core of the signal recognition particle. Science, 287, 2000
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1HQ1
| STRUCTURAL AND ENERGETIC ANALYSIS OF RNA RECOGNITION BY A UNIVERSALLY CONSERVED PROTEIN FROM THE SIGNAL RECOGNITION PARTICLE | Descriptor: | 4.5S RNA DOMAIN IV, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Batey, R.T, Sagar, M.B, Doudna, J.A. | Deposit date: | 2000-12-13 | Release date: | 2001-01-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle. J.Mol.Biol., 307, 2001
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5KPY
| Structure of a 5-hydroxytryptophan aptamer | Descriptor: | 5-hydroxy-L-tryptophan, 5-hydroxytryptophan RNA aptamer, IRIDIUM HEXAMMINE ION, ... | Authors: | Batey, R.T, Porter, E, Merck, M. | Deposit date: | 2016-07-05 | Release date: | 2017-01-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors. Nat. Chem. Biol., 13, 2017
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4FE5
| Crystal structure of the xpt-pbuX guanine riboswitch aptamer domain in complex with hypoxanthine | Descriptor: | ACETATE ION, COBALT HEXAMMINE(III), HYPOXANTHINE, ... | Authors: | Stoddard, C.D, Trausch, J.J, Widmann, J, Marcano, J, Knight, R, Batey, R.T. | Deposit date: | 2012-05-29 | Release date: | 2012-06-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine. Nature, 432, 2004
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3D0X
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6DN2
| CRYSTAL STRUCTURE OF THE FMN RIBOSWITCH BOUND TO BRX1354 SPLIT RNA | Descriptor: | 4-{benzyl[2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethyl]amino}butanoic acid, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Vicens, Q, Mondragon, E, Reyes, F.E, Berman, J, Kaur, H, Kells, K, Wickens, P, Wilson, J, Gadwood, R, Schostarez, H, Suto, R.K, Coish, P, Blount, K.F, Batey, R.T. | Deposit date: | 2018-06-05 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch. ACS Chem. Biol., 13, 2018
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6DN3
| CRYSTAL STRUCTURE OF THE FMN RIBOSWITCH BOUND TO BRX1555 SPLIT RNA | Descriptor: | 7,8-dimethyl-2,4-dioxo-10-(3-phenylpropyl)-1,2,3,4-tetrahydrobenzo[g]pteridin-10-ium, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Vicens, Q, Mondragon, E, Reyes, F.E, Berman, J, Kaur, H, Kells, K, Wickens, P, Wilson, J, Gadwood, R, Schostarez, H, Suto, R.K, Coish, P, Blount, K.F, Batey, R.T. | Deposit date: | 2018-06-05 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch. ACS Chem. Biol., 13, 2018
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6DN1
| CRYSTAL STRUCTURE OF THE FMN RIBOSWITCH BOUND TO BRX1151 SPLIT RNA | Descriptor: | 10-(6-carboxyhexyl)-8-(cyclopentylamino)-2,4-dihydroxy-7-methylbenzo[g]pteridin-10-ium, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Vicens, Q, Mondragon, E, Reyes, F.E, Berman, J, Kaur, H, Kells, K, Wickens, P, Wilson, J, Gadwood, R, Schostarez, H, Suto, R.K, Coish, P, Blount, K.F, Batey, R.T. | Deposit date: | 2018-06-05 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch. ACS Chem. Biol., 13, 2018
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3SD3
| The structure of the tetrahydrofolate riboswitch containing a U25C mutation | Descriptor: | IRIDIUM HEXAMMINE ION, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, Tetrahydrofolate riboswitch | Authors: | Reyes, F.E, Trausch, J.J, Ceres, P, Batey, R.T. | Deposit date: | 2011-06-08 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The structure of a tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer. Structure, 19, 2011
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4LVV
| Structure of the THF riboswitch | Descriptor: | N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, THF riboswitch | Authors: | Trausch, J.J, Batey, R.T. | Deposit date: | 2013-07-26 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21, 2014
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4LW0
| Structure of the THF riboswitch bound to adenine | Descriptor: | ADENINE, THF riboswitch | Authors: | Trausch, J.J, Batey, R.T. | Deposit date: | 2013-07-26 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.889 Å) | Cite: | A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21, 2014
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4LVW
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4LVX
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4LVZ
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4LVY
| Structure of the THF riboswitch bound to pemetrexed | Descriptor: | 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, THF riboswitch | Authors: | Trausch, J.J, Batey, R.T. | Deposit date: | 2013-07-26 | Release date: | 2014-03-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch. Chem.Biol., 21, 2014
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3NPQ
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3NPN
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6P2H
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4XWF
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4XW7
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4FRN
| Crystal structure of the cobalamin riboswitch regulatory element | Descriptor: | BARIUM ION, Cobalamin riboswitch aptamer domain, Hydroxocobalamin | Authors: | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | Deposit date: | 2012-06-26 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.43 Å) | Cite: | B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
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4FRG
| Crystal structure of the cobalamin riboswitch aptamer domain | Descriptor: | Hydroxocobalamin, IRIDIUM (III) ION, MAGNESIUM ION, ... | Authors: | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | Deposit date: | 2012-06-26 | Release date: | 2012-10-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
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4GMA
| Crystal structure of the adenosylcobalamin riboswitch | Descriptor: | Adenosylcobalamin, Adenosylcobalamin riboswitch | Authors: | Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. | Deposit date: | 2012-08-15 | Release date: | 2012-10-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.94 Å) | Cite: | B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
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