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8FCV
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BU of 8fcv by Molmil
Cryo-EM structure of TnsC-TniQ-DNA complex in type I-B CAST system
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (60-MER), MAGNESIUM ION, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FF5
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BU of 8ff5 by Molmil
Cryo-EM structure of Cascade-DNA-fullRloop in type I-B CAST system
Descriptor: Non-target DNA strand, Nostoc sp. 'Peltigera membranacea cyanobiont' 210A, RNA, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-07
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
8FCJ
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BU of 8fcj by Molmil
Cryo-EM structure of Cascade-DNA (P23) complex in type I-B CAST system
Descriptor: Non-target DNA strand, RNA, Target DNA strand, ...
Authors:Chang, L, Wang, S.
Deposit date:2022-12-01
Release date:2023-08-09
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Molecular mechanism for Tn7-like transposon recruitment by a type I-B CRISPR effector.
Cell, 186, 2023
6OIU
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BU of 6oiu by Molmil
X-ray crystal structure of the ectodomain of the Toxoplasma gondii ME49 Aminopeptidase N (TGME49_224350)
Descriptor: Aminopeptidase N, GLYCEROL, ZINC ION
Authors:McGowan, S, Drinkwater, N.
Deposit date:2019-04-09
Release date:2020-09-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2.
Biochem.J., 477, 2020
3Q44
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BU of 3q44 by Molmil
X-ray crystal structure of PfA-M1 bound to Bestatin derivative 16
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S, Greenbaum, D.C.
Deposit date:2010-12-22
Release date:2011-03-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the s1 pocket of the essential malaria m1 metalloaminopeptidase.
J.Med.Chem., 54, 2011
5U1A
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BU of 5u1a by Molmil
Ferritin with Gc MtrE loop 1 inserted at His34
Descriptor: CHLORIDE ION, FE (III) ION, Ferritin,MtrE protein chimera, ...
Authors:Wang, S.
Deposit date:2016-11-28
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based design of ferritin nanoparticle immunogens displaying antigenic loops of Neisseria gonorrhoeae.
FEBS Open Bio, 7, 2017
5UKY
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BU of 5uky by Molmil
DHp domain of PhoR of M. tuberculosis - native data
Descriptor: 1,2-ETHANEDIOL, ATP-binding protein, DI(HYDROXYETHYL)ETHER, ...
Authors:Wang, S.
Deposit date:2017-01-23
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Asymmetric Structure of the Dimerization Domain of PhoR, a Sensor Kinase Important for the Virulence of Mycobacterium tuberculosis.
ACS Omega, 2, 2017
3T8V
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BU of 3t8v by Molmil
A bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases
Descriptor: M1 family aminopeptidase, MAGNESIUM ION, N-[(2-{2-[(N-{(2S,3R)-3-amino-4-[4-(benzyloxy)phenyl]-2-hydroxybutanoyl}-L-alanyl)amino]ethoxy}ethoxy)acetyl]-4-benzoyl-L-phenylalanyl-N~6~-hex-5-ynoyllysinamide, ...
Authors:McGowan, S, Klemba, M, Greebaum, D.C.
Deposit date:2011-08-01
Release date:2011-09-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases
Proc.Natl.Acad.Sci.USA, 108, 2011
5U1B
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BU of 5u1b by Molmil
Ferritin with Gc MtrE loop2 inserted at the N-terminus
Descriptor: MtrE protein,Ferritin chimera
Authors:Wang, S.
Deposit date:2016-11-28
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structure-based design of ferritin nanoparticle immunogens displaying antigenic loops of Neisseria gonorrhoeae.
FEBS Open Bio, 7, 2017
3Q43
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BU of 3q43 by Molmil
X-ray crystal structure of PfA-M1 bound to bestatin derivative 15
Descriptor: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ...
Authors:McGowan, S, Greenbaum, D.C.
Deposit date:2010-12-22
Release date:2011-03-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the s1 pocket of the essential malaria m1 metalloaminopeptidase.
J.Med.Chem., 54, 2011
5UKV
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BU of 5ukv by Molmil
DHp domain of PhoR of M. tuberculosis - SeMet
Descriptor: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ATP-binding protein, ...
Authors:Wang, S.
Deposit date:2017-01-23
Release date:2017-12-06
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Asymmetric Structure of the Dimerization Domain of PhoR, a Sensor Kinase Important for the Virulence of Mycobacterium tuberculosis.
ACS Omega, 2, 2017
3T8W
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BU of 3t8w by Molmil
A bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases
Descriptor: CARBONATE ION, M17 leucyl aminopeptidase, N-((2R,3S,6S,18S,21S)-2-amino-18-(4-benzoylbenzyl)-21-carbamoyl-3-hydroxy-6-(naphthalen-2-ylmethyl)-4,7,16,19-tetraoxo-1-phenyl-11,14-dioxa-5,8,17,20-tetraazapentacosan-25-yl)hex-5-ynamide, ...
Authors:McGowan, S, Klemba, M, Greebaum, D.C.
Deposit date:2011-08-01
Release date:2011-09-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases
Proc.Natl.Acad.Sci.USA, 108, 2011
5ED4
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BU of 5ed4 by Molmil
Structure of a PhoP-DNA complex
Descriptor: 1,2-ETHANEDIOL, CACODYLATE ION, CALCIUM ION, ...
Authors:Wang, S.
Deposit date:2015-10-20
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of DNA sequence recognition by the response regulator PhoP in Mycobacterium tuberculosis.
Sci Rep, 6, 2016
2I8E
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BU of 2i8e by Molmil
Structure of SSO1404, a predicted DNA repair-associated protein from Sulfolobus solfataricus P2
Descriptor: Hypothetical protein, IODIDE ION
Authors:Wang, S, Zimmerman, M.D, Kudritska, M, Chruszcz, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-09-01
Release date:2006-09-26
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats.
J.Biol.Chem., 283, 2008
5TXJ
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BU of 5txj by Molmil
Polymorphic form 1 of amyloid-beta derived peptide - IFAEDV
Descriptor: amyloid-beta derived peptide
Authors:Sangwan, S, Sawaya, M.R, Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
5TXD
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BU of 5txd by Molmil
Structure of amyloid-beta derived peptide - NKGAIF
Descriptor: Amyloid beta A4 protein, PHOSPHATE ION
Authors:Sangwan, S, Sawaya, M.R, Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.452 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
5TXH
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BU of 5txh by Molmil
Polymorphic form 2 of amyloid-beta derived peptide - IFAEDV
Descriptor: IFAEDV, ISOPROPYL ALCOHOL
Authors:Sangwan, S, Sawaya, M.R, Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
4BYM
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BU of 4bym by Molmil
Structure of PhaZ7 PHB depolymerase Y105E mutant
Descriptor: CHLORIDE ION, PHB DEPOLYMERASE PHAZ7, SODIUM ION
Authors:Hermawan, S, Subedi, B, Papageorgiou, A.C, Jendrossek, D.
Deposit date:2013-07-20
Release date:2013-09-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.598 Å)
Cite:Biochemical Analysis and Structure Determination of Paucimonas Lemoignei Poly(3-Hydroxybutyrate) (Phb) Depolymerase Phaz7 Muteins Reveal the Phb Binding Site and Details of Substrate-Enzyme Interactions.
Mol.Microbiol., 90, 2013
5TZB
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BU of 5tzb by Molmil
Burkholderia sp. beta-aminopeptidase
Descriptor: CALCIUM ION, D-aminopeptidase
Authors:McGowan, S, Drinkwater, N, John, M, Dumsday, G.
Deposit date:2016-11-21
Release date:2017-07-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.977 Å)
Cite:Crystal structure of a beta-aminopeptidase from an Australian Burkholderia sp.
Acta Crystallogr F Struct Biol Commun, 73, 2017
4EME
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BU of 4eme by Molmil
X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase
Descriptor: M18 aspartyl aminopeptidase, ZINC ION
Authors:McGowan, S.
Deposit date:2012-04-11
Release date:2012-06-27
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP.
J.Mol.Biol., 422, 2012
4BTV
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BU of 4btv by Molmil
Structure of PhaZ7 PHB depolymerase in complex with 3HB trimer
Descriptor: (1R)-3-{[(1R)-3-METHOXY-1-METHYL-3-OXOPROPYL]OXY}-1-METHYL-3-OXOPROPYL (3R)-3-HYDROXYBUTANOATE, PHB DEPOLYMERASE PHAZ7
Authors:Hermawan, S, Subedi, B, Papageorgiou, A.C, Jendrossek, D.
Deposit date:2013-06-19
Release date:2013-09-18
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.594 Å)
Cite:Biochemical Analysis and Structure Determination of Paucimonas Lemoignei Poly(3-Hydroxybutyrate) (Phb) Depolymerase Phaz7 Muteins Reveal the Phb Binding Site and Details of Substrate-Enzyme Interactions.
Mol.Microbiol., 90, 2013
4OLR
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BU of 4olr by Molmil
[Leu-5]-Enkephalin mutant - YVVFV
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, [Leu-5]-Enkephalin mutant - YVVFV
Authors:Sangwan, S, Eisenberg, D, Sawaya, M.R, Do, T.D, Bowers, M.T, Lapointe, N.E, Teplow, D.B, Feinstein, S.C.
Deposit date:2014-01-24
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants.
J.Phys.Chem.B, 118, 2014
2MUR
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BU of 2mur by Molmil
Solution Structure of the Human FAAP20 UBZ-Ubiquitin Complex
Descriptor: Fanconi anemia-associated protein of 20 kDa, Ubiquitin, ZINC ION
Authors:Wang, S, Wojtaszek, J.L, Zhou, P.
Deposit date:2014-09-16
Release date:2014-12-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain.
Nucleic Acids Res., 42, 2014
2H4R
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BU of 2h4r by Molmil
Crystal structure of wildtype MENT in the native conformation
Descriptor: Heterochromatin-associated protein MENT
Authors:Irving, J.A, Whisstock, J.C, Buckle, A.M, McGowan, S.
Deposit date:2006-05-25
Release date:2006-07-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
2H4Q
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BU of 2h4q by Molmil
Crystal structure of a M-loop deletion variant of MENT in the cleaved conformation
Descriptor: Heterochromatin-associated protein MENT
Authors:Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A.
Deposit date:2006-05-25
Release date:2006-07-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006

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