3T8V

A bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases

Summary for 3T8V

Entry DOI	10.2210/pdb3t8v/pdb
Related	3EBG 3T8W
Descriptor	M1 family aminopeptidase, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	m1 alanyl-aminopeptidase, protease, metallo-aminopeptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Plasmodium falciparum
Cellular location	Cytoplasm: O96935
Total number of polymer chains	1
Total formula weight	105530.94
Authors	McGowan, S.,Klemba, M.,Greebaum, D.C. (deposition date: 2011-08-01, release date: 2011-09-28, Last modification date: 2024-03-20)
Primary citation	Harbut, M.B.,Velmourougane, G.,Dalal, S.,Reiss, G.,Whisstock, J.C.,Onder, O.,Brisson, D.,McGowan, S.,Klemba, M.,Greenbaum, D.C. Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases Proc.Natl.Acad.Sci.USA, 108:E526-E534, 2011 Cited by PubMed: 21844374 DOI: 10.1073/pnas.1105601108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation