7RGR
 
 | | Lysozyme 056 from Deep neural language modeling | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Artificial protein L056, CHLORIDE ION | | Authors: | Fraser, J.S, Holton, J.M, Olmos Jr, J.L, Greene, E.R. | | Deposit date: | 2021-07-15 | | Release date: | 2021-07-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Large language models generate functional protein sequences across diverse families.
Nat.Biotechnol., 2023
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7RH7
 | | Mycobacterial CIII2CIV2 supercomplex, Telacebec (Q203) bound | | Descriptor: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | Authors: | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | Deposit date: | 2021-07-16 | | Release date: | 2021-08-04 | | Last modified: | 2022-02-23 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
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7RH6
 | | Mycobacterial CIII2CIV2 supercomplex, inhibitor free, -Lpqe cyt cc open | | Descriptor: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | Authors: | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | Deposit date: | 2021-07-16 | | Release date: | 2021-08-04 | | Last modified: | 2021-11-17 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
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1FUU
 | | YEAST INITIATION FACTOR 4A | | Descriptor: | YEAST INITIATION FACTOR 4A | | Authors: | Caruthers, J.M, Johnson, E.R, McKay, D.B. | | Deposit date: | 2000-09-15 | | Release date: | 2000-11-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase.
Proc.Natl.Acad.Sci.USA, 97, 2000
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7RH5
 | | Mycobacterial CIII2CIV2 supercomplex, Inhibitor free | | Descriptor: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | Authors: | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | Deposit date: | 2021-07-16 | | Release date: | 2021-08-04 | | Last modified: | 2021-11-10 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
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1GH7
 | | CRYSTAL STRUCTURE OF THE COMPLETE EXTRACELLULAR DOMAIN OF THE BETA-COMMON RECEPTOR OF IL-3, IL-5, AND GM-CSF | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOKINE RECEPTOR COMMON BETA CHAIN, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Carr, P.D, Gustin, S.E, Church, A.P, Murphy, J.M, Ford, S.C, Mann, D.A, Woltring, D.M, Walker, I, Ollis, D.L, Young, I.G. | | Deposit date: | 2000-11-27 | | Release date: | 2001-11-28 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration.
Cell(Cambridge,Mass.), 104, 2001
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1FXV
 | | PENICILLIN ACYLASE MUTANT IMPAIRED IN CATALYSIS WITH PENICILLIN G IN THE ACTIVE SITE | | Descriptor: | CALCIUM ION, PENICILLIN ACYLASE, PENICILLIN G | | Authors: | Alkema, W.B, Hensgens, C.M, Kroezinga, E.H, de Vries, E, Floris, R, van der Laan, J.M, Dijkstra, B.W, Janssen, D.B. | | Deposit date: | 2000-09-27 | | Release date: | 2001-03-28 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.
Protein Eng., 13, 2000
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1G1P
 | | NMR Solution Structures of delta-Conotoxin EVIA from Conus ermineus that Selectively Acts on Vertebrate Neuronal Na+ Channels | | Descriptor: | CONOTOXIN EVIA | | Authors: | Volpon, L, Lamthanh, H, Barbier, J, Gilles, N, Molgo, J, Menez, A, Lancelin, J.M. | | Deposit date: | 2000-10-13 | | Release date: | 2000-11-01 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | NMR Solution Structures of delta-Conotoxin EVIA from Conus ermineus That Selectively Acts on Vertebrate Neuronal Na+ Channels.
J.Biol.Chem., 279, 2004
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7RJD
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in c position | | Descriptor: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | Authors: | Di Trani, J.M, Rubinstein, J.L. | | Deposit date: | 2021-07-20 | | Release date: | 2021-09-15 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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7RJA
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7RJE
 | | Complex III2 from Candida albicans, Inz-5 bound | | Descriptor: | 3-[2-fluoro-5-(trifluoromethyl)phenyl]-7-methyl-1-[(2-methyl-2H-tetrazol-5-yl)methyl]-1H-indazole, Cytochrome b, Cytochrome b-c1 complex subunit 2, ... | | Authors: | Di Trani, J.M, Rubinstein, J.L. | | Deposit date: | 2021-07-20 | | Release date: | 2021-09-15 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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7RJC
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in intermediate position | | Descriptor: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | Authors: | Di Trani, J.M, Rubinstein, J.L. | | Deposit date: | 2021-07-20 | | Release date: | 2021-09-15 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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7RJB
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in b position | | Descriptor: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | Authors: | Di Trani, J.M, Rubinstein, J.L. | | Deposit date: | 2021-07-20 | | Release date: | 2021-09-15 | | Last modified: | 2022-01-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
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1FUK
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1G6N
 | | 2.1 ANGSTROM STRUCTURE OF CAP-CAMP | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CATABOLITE GENE ACTIVATOR PROTEIN | | Authors: | Passner, J.M, Schultz, S.C, Steitz, T.A. | | Deposit date: | 2000-11-07 | | Release date: | 2000-12-15 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Modeling the cAMP-induced allosteric transition using the crystal structure of CAP-cAMP at 2.1 A resolution.
J.Mol.Biol., 304, 2000
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7RF5
 | | RT XFEL structure of Photosystem II 150 microseconds after the second illumination at 2.23 Angstrom resolution | | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | | Authors: | Hussein, R, Ibrahim, M, Bhowmick, A, Simon, P.S, Chatterjee, R, Lassalle, L, Doyle, M.D, Bogacz, I, Kim, I.-S, Cheah, M.H, Gul, S, de Lichtenberg, C, Chernev, P, Pham, C.C, Young, I.D, Carbajo, S, Fuller, F.D, Alonso-Mori, R, Batyuk, A, Sutherlin, K.D, Brewster, A.S, Bolotovski, R, Mendez, D, Holton, J.M, Moriarty, N.W, Adams, P.D, Bergmann, U, Sauter, N.K, Dobbek, H, Messinger, J, Zouni, A, Kern, J, Yachandra, V.K, Yano, J. | | Deposit date: | 2021-07-13 | | Release date: | 2021-11-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Structural dynamics in the water and proton channels of photosystem II during the S 2 to S 3 transition.
Nat Commun, 12, 2021
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7RF1
 | | RT XFEL structure of Photosystem II averaged across all S-states at 1.89 Angstrom resolution | | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | | Authors: | Hussein, R, Ibrahim, M, Bhowmick, A, Simon, P.S, Chatterjee, R, Lassalle, L, Doyle, M.D, Bogacz, I, Kim, I.-S, Cheah, M.H, Gul, S, de Lichtenberg, C, Chernev, P, Pham, C.C, Young, I.D, Carbajo, S, Fuller, F.D, Alonso-Mori, R, Batyuk, A, Sutherlin, K.D, Brewster, A.S, Bolotovski, R, Mendez, D, Holton, J.M, Moriarty, N.W, Adams, P.D, Bergmann, U, Sauter, N.K, Dobbek, H, Messinger, J, Zouni, A, Kern, J, Yachandra, V.K, Yano, J. | | Deposit date: | 2021-07-13 | | Release date: | 2021-11-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Structural dynamics in the water and proton channels of photosystem II during the S 2 to S 3 transition.
Nat Commun, 12, 2021
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7RES
 | | HUMAN IMPDH1 TREATED WITH ATP, IMP, AND NAD+, OCTAMER-CENTERED | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1, ... | | Authors: | Burrell, A.L, Kollman, J.M. | | Deposit date: | 2021-07-13 | | Release date: | 2022-01-12 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RGL
 | | HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH ATP, IMP, NAD+, INTERFACE-CENTERED | | Descriptor: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Burrell, A.L, Kollman, J.M. | | Deposit date: | 2021-07-15 | | Release date: | 2022-01-12 | | Last modified: | 2022-02-02 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RFI
 | | HUMAN RETINAL VARIANT IMPDH1(595) TREATED WITH GTP, ATP, IMP, NAD+, INTERFACE-CENTERED | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1, ... | | Authors: | Burrell, A.L, Kollman, J.M. | | Deposit date: | 2021-07-14 | | Release date: | 2022-01-12 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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1G2A
 | | THE CRYSTAL STRUCTURE OF E.COLI PEPTIDE DEFORMYLASE COMPLEXED WITH ACTINONIN | | Descriptor: | ACTINONIN, NICKEL (II) ION, POLYPEPTIDE DEFORMYLASE | | Authors: | Clements, J.M, Beckett, P, Brown, A, Catlin, C, Lobell, M, Palan, S, Thomas, W, Whittaker, M, Baker, P.J, Rodgers, H.F, Barynin, V, Rice, D.W, Hunter, M.G. | | Deposit date: | 2000-10-18 | | Release date: | 2001-10-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor.
Antimicrob.Agents Chemother., 45, 2001
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7RFH
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7RFG
 | | HUMAN IMPDH1 TREATED WITH GTP, IMP, AND NAD+ OCTAMER-CENTERED | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | Authors: | Burrell, A.L, Kollman, J.M. | | Deposit date: | 2021-07-14 | | Release date: | 2022-01-12 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RGQ
 | | HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH GTP, ATP, IMP, NAD+; INTERFACE-CENTERED | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | Authors: | Burrell, A.L, Kollman, J.M. | | Deposit date: | 2021-07-15 | | Release date: | 2022-01-12 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RFE
 | | HUMAN IMPDH1 TREATED WITH GTP, IMP, AND NAD+; INTERFACE-CENTERED | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | Authors: | Burrell, A.L, Kollman, J.M. | | Deposit date: | 2021-07-14 | | Release date: | 2022-01-12 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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