7BT5
 
 | | Crystal structure of plasmodium LysRS complexing with an antitumor compound | | Descriptor: | LYSINE, Lysine--tRNA ligase, N4-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-N2-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine | | Authors: | Zhou, J, Wang, J, Fang, P. | | Deposit date: | 2020-03-31 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.493 Å) | | Cite: | Inhibition of Plasmodium falciparum Lysyl-tRNA synthetase via an anaplastic lymphoma kinase inhibitor.
Nucleic Acids Res., 48, 2020
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2NPD
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2NPE
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2NMR
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2NOW
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2NPJ
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2NPC
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2NPK
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2NOP
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2NPG
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5JRE
 | | Crystal structure of NeC3PO in complex with ssDNA. | | Descriptor: | 9-METHYL-9H-PURIN-6-AMINE, ADENINE, NEQ131, ... | | Authors: | Gan, J, Zhang, J. | | Deposit date: | 2016-05-06 | | Release date: | 2016-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for single-stranded RNA recognition and cleavage by C3PO
Nucleic Acids Res., 44, 2016
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5JRC
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5JR9
 | | Crystal structure of apo-NeC3PO | | Descriptor: | NEQ131 | | Authors: | Zhang, J, Gan, J. | | Deposit date: | 2016-05-06 | | Release date: | 2016-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for single-stranded RNA recognition and cleavage by C3PO
Nucleic Acids Res., 44, 2016
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8GK7
 | | MsbA bound to cerastecin C | | Descriptor: | 2-[(4-butylbenzene-1-sulfonyl)amino]-5-[(3-{4-[(4-butylbenzene-1-sulfonyl)amino]-3-carboxyanilino}-3-oxopropyl)carbamoyl]benzoic acid, Lipid A export ATP-binding/permease protein MsbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Chen, Y, Klein, D. | | Deposit date: | 2023-03-17 | | Release date: | 2024-04-24 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii.
Nat Microbiol, 9, 2024
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8XZE
 | | Crystal structure of THF-II riboswitch with THF and soaked with Ir | | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, IRIDIUM ION, MAGNESIUM ION, ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 52, 2024
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8XZM
 | | Crystal structure of folE riboswitch with DHN | | Descriptor: | 2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 52, 2024
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8XZP
 | | Crystal structure of folE riboswitch with 8-CH3 Guanine | | Descriptor: | 2-azanyl-8-methyl-1,9-dihydropurin-6-one, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 52, 2024
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8XZQ
 | | Crystal structure of folE riboswitch with 8-N Guanine | | Descriptor: | 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 52, 2024
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9CSI
 | | A. baumannii MsbA Bound to Cerastecin Compound 5 | | Descriptor: | 3,3'-[(1,4-dioxobutane-1,4-diyl)bis(azanediyl)]bis[(4-butylbenzene-1-sulfonamido)benzoic acid], Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION, ... | | Authors: | Klein, D.J, Ishchenko, A, Soisson, S, Cheng, R, Hennig, M. | | Deposit date: | 2024-07-23 | | Release date: | 2024-09-04 | | Last modified: | 2024-10-02 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy.
J.Med.Chem., 67, 2024
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8XZN
 | | Crystal structure of folE riboswitch with BH4 | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 52, 2024
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8XZR
 | | Crystal structure of folE riboswitch with 8-NH2 Guanine | | Descriptor: | 8-AMINOGUANINE, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 52, 2024
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9CSG
 | | Human Serum Albumin Bound to Cerastecin Compound 5e | | Descriptor: | 2-(4-butylbenzene-1-sulfonamido)-5-(4-{3-carboxy-4-[4-(2-methoxyethyl)benzene-1-sulfonamido]anilino}-4-oxobutanamido)benzoic acid, Albumin, MYRISTIC ACID | | Authors: | Hruza, A, Klein, D.J, Ishchenko, A. | | Deposit date: | 2024-07-23 | | Release date: | 2024-09-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.914 Å) | | Cite: | Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy.
J.Med.Chem., 67, 2024
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8XZW
 | | Crystal structure of THF-II riboswitch with THF and soaked with Ir | | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 52, 2024
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8XZL
 | | Crystal structure of folE riboswitch with DHF | | Descriptor: | DIHYDROFOLIC ACID, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 52, 2024
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8XZK
 | | Crystal structure of folE riboswitch | | Descriptor: | RNA (53-MER) | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 52, 2024
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