6SXO
| Cryo-EM structure of the human Ebp1-ribosome complex | Descriptor: | 28S ribosomal RNA including ES27L-B (2839-3265), 5.8S ribosomal RNA, 60S ribosomal protein L19, ... | Authors: | Wild, K, Aleksic, M, Pfeffer, M, Sinning, I. | Deposit date: | 2019-09-26 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments. Nat Commun, 11, 2020
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6SR6
| Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein, ... | Authors: | Valentin Gese, G, Lapouge, K, Kopp, J, Sinning, I. | Deposit date: | 2019-09-05 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb. Nat Commun, 11, 2020
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6RYI
| WUS-HD bound to G-Box DNA | Descriptor: | DNA (5'-D(P*CP*CP*CP*AP*TP*CP*AP*CP*GP*TP*GP*AP*CP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*TP*CP*AP*CP*GP*TP*GP*AP*TP*GP*GP*G)-3'), Protein WUSCHEL | Authors: | Sloan, J.J, Wild, K, Sinning, I. | Deposit date: | 2019-06-10 | Release date: | 2020-04-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.691 Å) | Cite: | Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL. Nat Commun, 11, 2020
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6RYD
| WUS-HD bound to TGAA DNA | Descriptor: | DNA (5'-D(*AP*GP*TP*GP*TP*AP*TP*GP*AP*AP*TP*GP*AP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*TP*CP*AP*TP*TP*CP*AP*TP*AP*CP*AP*CP*T)-3'), MAGNESIUM ION, ... | Authors: | Sloan, J.J, Wild, K, Sinning, I. | Deposit date: | 2019-06-10 | Release date: | 2020-04-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.575 Å) | Cite: | Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL. Nat Commun, 11, 2020
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6RYL
| WUS-HD bound to TAAT DNA | Descriptor: | DNA (5'-D(P*CP*AP*CP*AP*AP*CP*CP*CP*AP*TP*TP*AP*AP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*TP*TP*AP*AP*TP*GP*GP*GP*TP*TP*GP*TP*G)-3'), Protein WUSCHEL | Authors: | Sloan, J.J, Wild, K, Sinning, I. | Deposit date: | 2019-06-10 | Release date: | 2020-04-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL. Nat Commun, 11, 2020
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5MB9
| Crystal structure of the eukaryotic ribosome associated complex (RAC), a unique Hsp70/Hsp40 pair | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Gumiero, A, Weyer, F.A, Valentin Gese, G, Lapouge, K, Sinning, I. | Deposit date: | 2016-11-07 | Release date: | 2016-12-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex. Nat. Struct. Mol. Biol., 24, 2017
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5M72
| Structure of the human SRP68-72 protein-binding domain complex | Descriptor: | GLYCEROL, POTASSIUM ION, SULFATE ION, ... | Authors: | Becker, M.M.M, Wild, K, Sinning, I. | Deposit date: | 2016-10-26 | Release date: | 2016-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction. Nucleic Acids Res., 45, 2017
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5M73
| Structure of the human SRP S domain with SRP72 RNA-binding domain | Descriptor: | GLYCEROL, Human gene for small cytoplasmic 7SL RNA (7L30.1), MAGNESIUM ION, ... | Authors: | Becker, M.M.M, Wild, K, Sinning, I. | Deposit date: | 2016-10-26 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction. Nucleic Acids Res., 45, 2017
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5NNR
| Structure of Naa15/Naa10 bound to HypK-THB | Descriptor: | HypK, N-terminal acetyltransferase-like protein, Naa10 | Authors: | Weyer, F.A, Gumiero, A, Kopp, J, Sinning, I. | Deposit date: | 2017-04-10 | Release date: | 2017-06-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis of HypK regulating N-terminal acetylation by the NatA complex. Nat Commun, 8, 2017
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5NIY
| Signal recognition particle-docking protein FtsY | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Signal recognition particle-docking protein FtsY | Authors: | Kempf, G, Stjepanovic, G, Lapouge, K, Sinning, I. | Deposit date: | 2017-03-27 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Escherichia coli SRP Receptor Forms a Homodimer at the Membrane. Structure, 26, 2018
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5NNP
| Structure of Naa15/Naa10 bound to HypK-THB | Descriptor: | CARBOXYMETHYL COENZYME *A, GLYCEROL, N-terminal acetyltransferase-like protein, ... | Authors: | Weyer, F.A, Gumiero, A, Kopp, J, Sinning, I. | Deposit date: | 2017-04-10 | Release date: | 2017-06-14 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | Structural basis of HypK regulating N-terminal acetylation by the NatA complex. Nat Commun, 8, 2017
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5N1A
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5NQH
| Structure of the human Fe65-PTB2 homodimer | Descriptor: | Amyloid beta A4 precursor protein-binding family B member 1, GLYCEROL, SULFATE ION | Authors: | Feilen, L.P, Haubrich, K, Sinning, I, Konietzko, U, Kins, S, Simon, B, Wild, K. | Deposit date: | 2017-04-20 | Release date: | 2017-05-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction. Front Mol Neurosci, 10, 2017
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5O9E
| Crystal structure of the Imp4-Mpp10 complex from Chaetomium thermophilum | Descriptor: | 1,2-ETHANEDIOL, Putative U3 small nucleolar ribonucleoprotein, Putative U3 small nucleolar ribonucleoprotein protein | Authors: | Kharde, S, Ahmed, Y.L, Sinning, I. | Deposit date: | 2017-06-19 | Release date: | 2017-08-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.884 Å) | Cite: | Mpp10 represents a platform for the interaction of multiple factors within the 90S pre-ribosome. PLoS ONE, 12, 2017
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5M3Q
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5M43
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5ONS
| Crystal structure of the minimal DENR-MCTS1 complex | Descriptor: | Density-regulated protein, GLYCEROL, Malignant T-cell-amplified sequence 1, ... | Authors: | Ahmed, Y.L, Sinning, I. | Deposit date: | 2017-08-04 | Release date: | 2018-05-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | DENR-MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation. PLoS Biol., 16, 2018
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1QZW
| Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication | Descriptor: | 7S RNA, Signal recognition 54 kDa protein | Authors: | Rosendal, K.R, Wild, K, Montoya, G, Sinning, I. | Deposit date: | 2003-09-18 | Release date: | 2003-11-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication Proc.Natl.Acad.Sci.USA, 100, 2003
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1QZX
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2FH5
| The Structure of the Mammalian SRP Receptor | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Signal recognition particle receptor alpha subunit, ... | Authors: | Schlenker, O, Wild, K, Sinning, I. | Deposit date: | 2005-12-23 | Release date: | 2006-01-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | The structure of the mammalian signal recognition particle (SRP) receptor as prototype for the interaction of small GTPases with Longin domains. J.Biol.Chem., 281, 2006
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3SJC
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3SJA
| Crystal structure of S. cerevisiae Get3 in the open state in complex with Get1 cytosolic domain | Descriptor: | ATPase GET3, Golgi to ER traffic protein 1, PHOSPHATE ION, ... | Authors: | Reitz, S, Wild, K, Sinning, I. | Deposit date: | 2011-06-21 | Release date: | 2011-07-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science, 333, 2011
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3SJB
| Crystal structure of S. cerevisiae Get3 in the open state in complex with Get1 cytosolic domain | Descriptor: | ATPase GET3, Golgi to ER traffic protein 1, PHOSPHATE ION, ... | Authors: | Reitz, S, Wild, K, Sinning, I. | Deposit date: | 2011-06-21 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science, 333, 2011
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3SJD
| Crystal structure of S. cerevisiae Get3 with bound ADP-Mg2+ in complex with Get2 cytosolic domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 2, ... | Authors: | Reitz, S, Wild, K, Sinning, I. | Deposit date: | 2011-06-21 | Release date: | 2011-07-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.6 Å) | Cite: | Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex. Science, 333, 2011
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3SYN
| Crystal structure of FlhF in complex with its activator | Descriptor: | ALUMINUM FLUORIDE, ATP-binding protein YlxH, Flagellar biosynthesis protein flhF, ... | Authors: | Bange, G, Kuemmerer, N, Wild, K, Sinning, I. | Deposit date: | 2011-07-18 | Release date: | 2011-11-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.063 Å) | Cite: | Structural basis for the molecular evolution of SRP-GTPase activation by protein. Nat.Struct.Mol.Biol., 18, 2011
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