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1G0Z
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BU of 1g0z by Molmil
SPECIFIC MUTATIONS IN KRAIT PLA2 LEAD TO DIMERIZATION OF PROTEIN MOLECULES: CRYSTAL STRUCTURE OF KRAIT PLA2 AT 2.1 RESOLUTION
Descriptor: CHLORIDE ION, PHOSPHOLIPASE A2
Authors:Singh, T.P, Gourinath, S, Sharma, S, Singh, G.
Deposit date:2000-10-10
Release date:2003-06-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Specific mutations in Krait PLA2 lead to dimerization of protein molecules: Crystal structure of Krait PLA2 at 2.1 resolution.
To be Published
5ABJ
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BU of 5abj by Molmil
Structure of Coxsackievirus A16 in complex with GPP3
Descriptor: 1-[(3S)-5-[4-[(E)-ETHOXYIMINOMETHYL]PHENOXY]-3-METHYL-PENTYL]-3-PYRIDIN-4-YL-IMIDAZOLIDIN-2-ONE, CHLORIDE ION, SODIUM ION, ...
Authors:De Colibus, L, Wang, X, Tijsma, A, Neyts, J, Spyrou, J.A.B, Ren, J, Grimes, J.M, Puerstinger, G, Leyssen, P, Fry, E.E, Rao, Z, Stuart, D.I.
Deposit date:2015-08-06
Release date:2015-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure Elucidation of Coxsackievirus A16 in Complex with Gpp3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses.
Plos Pathog., 11, 2015
2AXD
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BU of 2axd by Molmil
solution structure of the theta subunit of escherichia coli DNA polymerase III in complex with the epsilon subunit
Descriptor: DNA polymerase III, theta subunit
Authors:Keniry, M.A, Park, A.Y, Owen, E.A, Hamdan, S.M, Pintacuda, G, Otting, G, Dixon, N.E.
Deposit date:2005-09-05
Release date:2006-07-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the theta subunit of Escherichia coli DNA polymerase III in complex with the epsilon subunit
J.Bacteriol., 188, 2006
5D5K
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BU of 5d5k by Molmil
Crystal Structure NLS from human PARP-2 complexed with Importin alpha delta IBB
Descriptor: Importin subunit alpha-1, Poly [ADP-ribose] polymerase 2
Authors:Riccio, A.A, Cingolani, G, Pascal, J.M.
Deposit date:2015-08-10
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage.
Nucleic Acids Res., 44, 2016
1TUH
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BU of 1tuh by Molmil
Structure of Bal32a from a Soil-Derived Mobile Gene Cassette
Descriptor: ACETATE ION, hypothetical protein EGC068
Authors:Robinson, A, Wu, P.S.-C, Harrop, S.J, Schaeffer, P.M, Dixon, N.E, Gillings, M.R, Holmes, A.J, Nevalainen, K.M.H, Otting, G, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C.
Deposit date:2004-06-25
Release date:2004-07-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Integron-associated Mobile Gene Cassettes Code for Folded Proteins: The Structure of Bal32a, a New Member of the Adaptable alpha+beta Barrel Family
J.Mol.Biol., 346, 2005
1HOM
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BU of 1hom by Molmil
DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: ANTENNAPEDIA PROTEIN
Authors:Qian, Y.-Q, Billeter, M, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K.
Deposit date:1991-10-08
Release date:1993-10-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Determination of the three-dimensional structure of the Antennapedia homeodomain from Drosophila in solution by 1H nuclear magnetic resonance spectroscopy.
J.Mol.Biol., 214, 1990
2DDI
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BU of 2ddi by Molmil
NMR structure of the second Kunitz domain of human WFIKKN1
Descriptor: WAP, follistatin/kazal, immunoglobulin, ...
Authors:Liepinsh, E, Otting, G.
Deposit date:2006-01-30
Release date:2006-12-19
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein
J.Biomol.Nmr, 35, 2006
1J5B
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BU of 1j5b by Molmil
Solution structure of a hydrophobic analogue of the winter flounder antifreeze protein
Descriptor: Antifreeze protein type 1 analogue
Authors:Liepinsh, E, Otting, G, Harding, M.M, Ward, L.G, Mackay, J.P, Haymet, A.D.
Deposit date:2002-03-22
Release date:2002-03-27
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of a hydrophobic analogue of the winter flounder antifreeze protein.
Eur.J.Biochem., 269, 2002
2DDJ
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BU of 2ddj by Molmil
NMR structure of the second Kunitz domain of human WFIKKN1
Descriptor: WAP, follistatin/kazal, immunoglobulin, ...
Authors:Liepinsh, E, Otting, G.
Deposit date:2006-01-30
Release date:2006-12-19
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein
J.Biomol.Nmr, 35, 2006
1F4K
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BU of 1f4k by Molmil
CRYSTAL STRUCTURE OF THE REPLICATION TERMINATOR PROTEIN/B-SITE DNA COMPLEX
Descriptor: 5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*AP*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*GP*AP*AP*CP*AP*TP*TP*AP*TP*GP*TP*TP*CP*AP*TP*AP*G)-3', REPLICATION TERMINATION PROTEIN
Authors:Wilce, J.A, Vivian, J.P, Hastings, A.F, Otting, G, Folmer, R.H.A, Duggin, I.G, Wake, R.G, Wilce, M.C.J.
Deposit date:2000-06-08
Release date:2001-06-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the RTP-DNA complex and the mechanism of polar replication fork arrest
Nat.Struct.Biol., 8, 2001
3RWN
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BU of 3rwn by Molmil
Atomic structure of bacteriophage sf6 tail needle knob
Descriptor: GLUTAMIC ACID, Gene 9 protein, PHOSPHATE ION
Authors:Bhardwaj, A, Cingolani, G.
Deposit date:2011-05-09
Release date:2011-06-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1 Å)
Cite:Atomic structure of bacteriophage Sf6 tail needle knob.
J.Biol.Chem., 286, 2011
5TL8
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BU of 5tl8 by Molmil
Naegleria fowleri CYP51-posaconazole complex
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, POSACONAZOLE, ...
Authors:Podust, L.M, Jennings, G, Calvet-Alvarez, C, Debnath, A.
Deposit date:2016-10-10
Release date:2017-10-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structure of the Naegleria fowleri CYP51 at 1.7 Angstroms resolution
To be published
1FZD
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BU of 1fzd by Molmil
STRUCTURE OF RECOMBINANT ALPHAEC DOMAIN FROM HUMAN FIBRINOGEN-420
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Spraggon, G, Applegate, D, Everse, S.J, Zhang, J.-Z, Veerapandian, L, Redman, C, Doolittle, R.F, Grieninger, G.
Deposit date:1998-06-22
Release date:1998-08-19
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a recombinant alphaEC domain from human fibrinogen-420.
Proc.Natl.Acad.Sci.USA, 95, 1998
1UCP
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BU of 1ucp by Molmil
NMR structure of the PYRIN domain of human ASC
Descriptor: Apoptosis-associated speck-like protein containing a CARD
Authors:Liepinsh, E, Barbals, R, Dahl, E, Sharipo, A, Staub, E, Otting, G.
Deposit date:2003-04-16
Release date:2003-11-04
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
J.Mol.Biol., 332, 2003
3Q5U
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BU of 3q5u by Molmil
A minimal NLS from human scramblase 4 complexed with importin alpha
Descriptor: Importin subunit alpha-2, Phospholipid scramblase 4
Authors:Bhardwaj, A, Cingolani, G.
Deposit date:2010-12-29
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Minimal Nuclear Localization Signal (NLS) in Human Phospholipid Scramblase 4 That Binds Only the Minor NLS-binding Site of Importin {alpha}1.
J.Biol.Chem., 286, 2011
4L74
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BU of 4l74 by Molmil
Ca2+-bound MthK RCK domain at 1.9 Angstrom with single ligand
Descriptor: CALCIUM ION, Calcium-gated potassium channel MthK
Authors:Smith, F.J, Cingolani, G, Rothberg, B.S.
Deposit date:2013-06-13
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.841 Å)
Cite:Structural basis of allosteric interactions among Ca(2+)-binding sites in a K(+) channel RCK domain.
Nat Commun, 4, 2013
4LIN
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BU of 4lin by Molmil
Exploring the atomic structure and conformational flexibility of a 320 angstrom long engineered viral fiber using X-ray crystallography
Descriptor: CALCIUM ION, CHLORIDE ION, Tail needle protein gp26
Authors:Bhardwaj, A, Cingolani, G.
Deposit date:2013-07-02
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Exploring the atomic structure and conformational flexibility of a 320 angstrom long engineered viral fiber using X-ray crystallography.
Acta Crystallogr.,Sect.D, 70, 2014
5T94
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BU of 5t94 by Molmil
Crystal structure of Kap60 bound to yeast RCC1 (Prp20)
Descriptor: Guanine nucleotide exchange factor SRM1, Importin subunit alpha
Authors:Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
Deposit date:2016-09-09
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.631 Å)
Cite:Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017
1G7D
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BU of 1g7d by Molmil
NMR STRUCTURE OF ERP29 C-DOMAIN
Descriptor: ENDOPLASMIC RETICULUM PROTEIN ERP29
Authors:Liepinsh, E, Mkrtchian, S, Barishev, M, Sharipo, A, Ingelman-Sundberg, M, Otting, G.
Deposit date:2000-11-10
Release date:2000-11-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Thioredoxin fold as homodimerization module in the putative chaperone ERp29: NMR structures of the domains and experimental model of the 51 kDa dimer.
Structure, 9, 2001
4MBB
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BU of 4mbb by Molmil
Cubic crystal form of PIR1 dual specificity phosphatase core
Descriptor: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2013-08-19
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
2AYA
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BU of 2aya by Molmil
Solution Structure of the C-Terminal 14 kDa Domain of the tau subunit from Escherichia coli DNA Polymerase III
Descriptor: DNA polymerase III subunit tau
Authors:Jergic, S, Dixon, N.E, Otting, G, Su, X.C.
Deposit date:2005-09-07
Release date:2006-11-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of Domains IVa and V of the tau subunit of Escherichia coli DNA polymerase III and interaction with the alpha subunit.
Nucleic Acids Res., 35, 2007
5V5O
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BU of 5v5o by Molmil
Structure of NLS2K of influenza A virus nucleoprotein bound to importin alpha
Descriptor: Importin subunit alpha-1, Nucleoprotein
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.243 Å)
Cite:Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
4KEF
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BU of 4kef by Molmil
Structure of Cofilin Mutant (cof1-159p)
Descriptor: Cofilin
Authors:Kish-Trier, E, Haarer, B, Cingolani, G, Amberg, D.C.
Deposit date:2013-04-25
Release date:2013-05-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.098 Å)
Cite:Structure of Cofilin Mutant (cof1-159p)
To be Published
1G7E
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BU of 1g7e by Molmil
NMR STRUCTURE OF N-DOMAIN OF ERP29 PROTEIN
Descriptor: ENDOPLASMIC RETICULUM PROTEIN ERP29
Authors:Liepinsh, E, Mkrtchian, S, Barishev, M, Sharipo, M, Ingelman-Sundberg, M, Otting, G.
Deposit date:2000-11-10
Release date:2000-11-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Thioredoxin fold as homodimerization module in the putative chaperone ERp29: NMR structures of the domains and experimental model of the 51 kDa dimer.
Structure, 9, 2001
5TBK
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BU of 5tbk by Molmil
Crystal structure of human importin a3 bound to RCC1
Descriptor: Importin subunit alpha-3, Regulator of chromosome condensation
Authors:Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.
Nat Commun, 8, 2017

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