8W4C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8w4c by Molmil](/molmil-images/mine/8w4c) | The sigma-1 receptor from Xenopus laevis in complex with progesterone by soaking | Descriptor: | PROGESTERONE, Sigma non-opioid intracellular receptor 1 | Authors: | Xiao, Y, Fu, C, Sun, Z, Zhou, X. | Deposit date: | 2023-08-23 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.676 Å) | Cite: | Insight into binding of endogenous neurosteroid ligands to the sigma-1 receptor. Nat Commun, 15, 2024
|
|
8W4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8w4d by Molmil](/molmil-images/mine/8w4d) | |
8W4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8w4b by Molmil](/molmil-images/mine/8w4b) | The sigma-1 receptor from Xenopus laevis in complex with progesterone by co-crystallization | Descriptor: | PROGESTERONE, Sigma non-opioid intracellular receptor 1 | Authors: | Xiao, Y, Fu, C, Sun, Z, Zhou, X. | Deposit date: | 2023-08-23 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | Insight into binding of endogenous neurosteroid ligands to the sigma-1 receptor. Nat Commun, 15, 2024
|
|
8WWB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8wwb by Molmil](/molmil-images/mine/8wwb) | |
7D5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d5i by Molmil](/molmil-images/mine/7d5i) | Structure of Mycobacterium smegmatis bd complex in the apo-form. | Descriptor: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome D ubiquinol oxidase subunit 1, HEME B/C, ... | Authors: | Wang, W, Gong, H, Gao, Y, Zhou, X, Rao, Z. | Deposit date: | 2020-09-26 | Release date: | 2021-06-23 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels. Nat Commun, 12, 2021
|
|
7CYG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cyg by Molmil](/molmil-images/mine/7cyg) | Crystal structure of a cysteine-pair mutant (Y113C-P190C) of a bacterial bile acid transporter before disulfide bond formation | Descriptor: | Transporter, sodium/bile acid symporter family | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-09-03 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.198 Å) | Cite: | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter. Acta Crystallogr D Struct Biol, 77, 2021
|
|
7CYK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cyk by Molmil](/molmil-images/mine/7cyk) | Crystal structure of a second cysteine-pair mutant (V110C-I197C) of a bacterial bile acid transporter before disulfide bond formation | Descriptor: | MERCURY (II) ION, Transporter, sodium/bile acid symporter family | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-09-03 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.785 Å) | Cite: | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter. Acta Crystallogr D Struct Biol, 77, 2021
|
|
7Y96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y96 by Molmil](/molmil-images/mine/7y96) | |
7Y9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y9b by Molmil](/molmil-images/mine/7y9b) | Crystal structure of the membrane (M) protein of a SARS-COV-2-related coronavirus | Descriptor: | 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, Membrane protein | Authors: | Wang, X, Sun, Z, Zhou, X. | Deposit date: | 2022-06-24 | Release date: | 2022-08-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.214 Å) | Cite: | Crystal structure of the membrane (M) protein from a bat betacoronavirus. Pnas Nexus, 2, 2023
|
|
8HUZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8huz by Molmil](/molmil-images/mine/8huz) | |
8JIX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jix by Molmil](/molmil-images/mine/8jix) | |
8JED
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jed by Molmil](/molmil-images/mine/8jed) | Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors | Descriptor: | mRNA-capping enzyme regulatory subunit OPG124 | Authors: | Wang, D, Zhao, R, Shu, W, Hu, W, Wang, M, Cao, J, Zhou, X. | Deposit date: | 2023-05-15 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors. Int.J.Biol.Macromol., 253, 2023
|
|
7DIX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dix by Molmil](/molmil-images/mine/7dix) | Crystal structure of LeuT in lipidic cubic phase at pH 5 | Descriptor: | Na(+):neurotransmitter symporter (Snf family), SELENOMETHIONINE, SODIUM ION | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
|
|
7DII
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dii by Molmil](/molmil-images/mine/7dii) | Crystal structure of LeuT in lipidic cubic phase at pH 7 | Descriptor: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
|
|
7DJ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dj2 by Molmil](/molmil-images/mine/7dj2) | Crystal structure of the G26C/E290S mutant of LeuT | Descriptor: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
|
|
7DJC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7djc by Molmil](/molmil-images/mine/7djc) | Crystal structure of the G26C/Q250A mutant of LeuT | Descriptor: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-20 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
|
|
7W2B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w2b by Molmil](/molmil-images/mine/7w2b) | |
7W2C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w2c by Molmil](/molmil-images/mine/7w2c) | The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084 | Descriptor: | 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate, GOLD ION, Sigma non-opioid intracellular receptor 1, ... | Authors: | Meng, F, Sun, Z, Zhou, X. | Deposit date: | 2021-11-23 | Release date: | 2022-03-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.335 Å) | Cite: | An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway. Nat Commun, 13, 2022
|
|
7W2E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w2e by Molmil](/molmil-images/mine/7w2e) | |
7W2G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w2g by Molmil](/molmil-images/mine/7w2g) | |
7W2H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w2h by Molmil](/molmil-images/mine/7w2h) | |
7W2D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w2d by Molmil](/molmil-images/mine/7w2d) | |
7W2F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w2f by Molmil](/molmil-images/mine/7w2f) | |
7F5X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f5x by Molmil](/molmil-images/mine/7f5x) | GK domain of Drosophila P5CS filament with glutamate | Descriptor: | Delta-1-pyrroline-5-carboxylate synthase, GAMMA-L-GLUTAMIC ACID | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2021-06-23 | Release date: | 2022-04-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
|
|
7F5V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7f5v by Molmil](/molmil-images/mine/7f5v) | Drosophila P5CS filament with glutamate, ATP, and NADPH | Descriptor: | Delta-1-pyrroline-5-carboxylate synthase | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2021-06-22 | Release date: | 2022-04-06 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
|
|