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6OA9
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BU of 6oa9 by Molmil
Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Twomey, E.C, Ji, Z, Wales, T.E, Bodnar, N.O, Engen, J.R, Rapoport, T.A.
Deposit date:2019-03-15
Release date:2019-07-03
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding.
Science, 365, 2019
5ES1
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BU of 5es1 by Molmil
CRYSTAL STRUCTURE OF MICROTUBULE AFFINITY-REGULATING KINASE 4 CATALYTIC DOMAIN IN COMPLEX WITH A PYRAZOLOPYRIMIDINE INHIBITOR
Descriptor: MAP/microtubule affinity-regulating kinase 4, ~{N}-[(1~{R},6~{R})-6-azanyl-2,2-bis(fluoranyl)cyclohexyl]-5-ethyl-4-[6-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]thiophene-2-carboxamide
Authors:Sack, J.S.
Deposit date:2015-11-16
Release date:2015-12-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor.
Acta Crystallogr F Struct Biol Commun, 72, 2016
2Z4B
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BU of 2z4b by Molmil
Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand
Descriptor: (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL, Estrogen receptor beta
Authors:Wang, Y.
Deposit date:2007-06-14
Release date:2007-08-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: Synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification.
Bioorg.Med.Chem.Lett., 17, 2007
5F16
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BU of 5f16 by Molmil
CTA-modified hen egg-white lysozyme
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:McGlone, C, Nix, J.C, Page, R.C.
Deposit date:2015-11-30
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Investigating the Impact of Polymer Functional Groups on the Stability and Activity of Lysozyme-Polymer Conjugates.
Biomacromolecules, 17, 2016
6OBZ
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BU of 6obz by Molmil
Crystal structure of FluA-20 Fab
Descriptor: Heavy chain of FluA-20 Fab, Light chain of FluA-20 Fab, Immunoglobulin light chain
Authors:Wilson, I.A, Lang, S.
Deposit date:2019-03-21
Release date:2019-05-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface.
Cell, 177, 2019
6OIT
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BU of 6oit by Molmil
CryoEM structure of Arabidopsis DDR' complex (DRD1 peptide-DMS3-RDM1)
Descriptor: Protein CHROMATIN REMODELING 35, Protein DEFECTIVE IN MERISTEM SILENCING 3, Protein RDM1
Authors:Wongpalee, S.P, Liu, S, Zhou, Z.H, Jacobsen, S.E.
Deposit date:2019-04-09
Release date:2019-07-24
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation.
Nat Commun, 10, 2019
6OKZ
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BU of 6okz by Molmil
Structure of VcINDY bound to Fumarate
Descriptor: FUMARIC ACID, SODIUM ION, Transporter, ...
Authors:Sauer, D.B, Marden, J, Wang, D.N.
Deposit date:2019-04-15
Release date:2020-10-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.292 Å)
Cite:Elevator mechanism dynamics in a sodium-coupled dicarboxylate transporter
Biorxiv, 2022
6ONP
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BU of 6onp by Molmil
Crystal structure of periplasmic binding protein XoxJ from Methylobacterium extorquens AM1
Descriptor: 1,2-ETHANEDIOL, periplasmic binding protein XoxJ
Authors:Rose, H.R, Taylor, E.M, Boal, A.K.
Deposit date:2019-04-22
Release date:2019-05-08
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Biochemical and Structural Characterization of XoxG and XoxJ and Their Roles in Lanthanide-Dependent Methanol Dehydrogenase Activity.
Chembiochem, 20, 2019
6ONQ
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BU of 6onq by Molmil
Crystal structure of c-type cytochrome XoxG from Methylobacterium extorquens AM1
Descriptor: Cytochrome c XoxG, HEME C
Authors:McBride, M.J, Featherston, E.R, Boal, A.K.
Deposit date:2019-04-22
Release date:2019-05-08
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Biochemical and Structural Characterization of XoxG and XoxJ and Their Roles in Lanthanide-Dependent Methanol Dehydrogenase Activity.
Chembiochem, 20, 2019
2CD8
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BU of 2cd8 by Molmil
Crystal structure of YC-17-bound cytochrome P450 PikC (CYP107L1)
Descriptor: 4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, CYTOCHROME P450 MONOOXYGENASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Yermalitskaya, L.I, Kim, Y, Sherman, D.H, Waterman, M.R, Podust, L.M.
Deposit date:2006-01-20
Release date:2007-02-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae.
J.Biol.Chem., 281, 2006
6OT9
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BU of 6ot9 by Molmil
Bimetallic dodecameric cage design 1 (BMC1) from cytochrome cb562
Descriptor: ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ...
Authors:Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A.
Deposit date:2019-05-02
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Constructing protein polyhedra via orthogonal chemical interactions.
Nature, 578, 2020
3AVH
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BU of 3avh by Molmil
Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site
Descriptor: ACETIC ACID, CHLORIDE ION, Integrase, ...
Authors:Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I.
Deposit date:2011-03-05
Release date:2012-01-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site.
Chembiochem, 12, 2011
5FP3
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BU of 5fp3 by Molmil
Cell penetrant inhibitors of the JMJD2 (KDM4) and JARID1 (KDM5) families of histone lysine demethylases
Descriptor: 3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid, BICINE, COBALT (II) ION, ...
Authors:Chung, C.
Deposit date:2015-11-27
Release date:2016-01-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Cell Penetrant Inhibitors of the Kdm4 and Kdm5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives.
J.Med.Chem., 59, 2016
3AV9
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BU of 3av9 by Molmil
Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site
Descriptor: ACETIC ACID, CHLORIDE ION, Integrase, ...
Authors:Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I.
Deposit date:2011-03-02
Release date:2012-01-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site.
Chembiochem, 12, 2011
3AVF
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BU of 3avf by Molmil
Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site
Descriptor: ACETIC ACID, CHLORIDE ION, Integrase, ...
Authors:Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I.
Deposit date:2011-03-05
Release date:2012-01-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site.
Chembiochem, 12, 2011
3AVN
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BU of 3avn by Molmil
Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site
Descriptor: ACETIC ACID, CHLORIDE ION, Integrase, ...
Authors:Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I.
Deposit date:2011-03-05
Release date:2012-01-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site.
Chembiochem, 12, 2011
6OT4
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BU of 6ot4 by Molmil
Bimetallic dodecameric cage design 2 (BMC2) from cytochrome cb562
Descriptor: ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ...
Authors:Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A.
Deposit date:2019-05-02
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Constructing protein polyhedra via orthogonal chemical interactions.
Nature, 578, 2020
3AVL
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BU of 3avl by Molmil
Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site
Descriptor: ACETIC ACID, CHLORIDE ION, Integrase, ...
Authors:Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I.
Deposit date:2011-03-05
Release date:2012-01-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site.
Chembiochem, 12, 2011
6OT7
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BU of 6ot7 by Molmil
Bimetallic dodecameric cage design 3 (BMC3) from cytochrome cb562
Descriptor: ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ...
Authors:Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A.
Deposit date:2019-05-02
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Constructing protein polyhedra via orthogonal chemical interactions.
Nature, 578, 2020
6OT8
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BU of 6ot8 by Molmil
Bimetallic hexameric cage design 4 (BMC4) from cytochrome cb562
Descriptor: ACETOHYDROXAMIC ACID, FE (III) ION, HEME C, ...
Authors:Golub, E, Esselborn, J, Bailey, J.B, Tezcan, F.A.
Deposit date:2019-05-02
Release date:2020-01-29
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Constructing protein polyhedra via orthogonal chemical interactions.
Nature, 578, 2020
5FP4
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BU of 5fp4 by Molmil
Crystal structure of human KDM4D in complex with 3-(4- phenylbutanamido)pyridine-4-carboxylic acid
Descriptor: 3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid, FE (II) ION, GLYCEROL, ...
Authors:Chung, C.
Deposit date:2015-11-27
Release date:2016-01-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cell Penetrant Inhibitors of the Kdm4 and Kdm5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives.
J.Med.Chem., 59, 2016
3AVA
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BU of 3ava by Molmil
Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site
Descriptor: ACETIC ACID, CHLORIDE ION, Integrase, ...
Authors:Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I.
Deposit date:2011-03-02
Release date:2012-01-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site.
Chembiochem, 12, 2011
3AVI
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BU of 3avi by Molmil
Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site
Descriptor: ACETIC ACID, CHLORIDE ION, Integrase, ...
Authors:Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I.
Deposit date:2011-03-05
Release date:2012-02-15
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site.
Chembiochem, 12, 2011
3AVB
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BU of 3avb by Molmil
Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site
Descriptor: ACETIC ACID, CHLORIDE ION, Integrase, ...
Authors:Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I.
Deposit date:2011-03-02
Release date:2012-01-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site.
Chembiochem, 12, 2011
3AVJ
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BU of 3avj by Molmil
Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site
Descriptor: ACETIC ACID, CHLORIDE ION, Integrase, ...
Authors:Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I.
Deposit date:2011-03-05
Release date:2012-01-18
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site.
Chembiochem, 12, 2011

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