2CD8

Crystal structure of YC-17-bound cytochrome P450 PikC (CYP107L1)

Summary for 2CD8

Entry DOI	10.2210/pdb2cd8/pdb
Related	2BVJ 2C6H 2C7X 2CA0
Descriptor	CYTOCHROME P450 MONOOXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, 4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, ... (4 entities in total)
Functional Keywords	oxidoreductase, cytochrome p450, pikc, yc-17, macrolide monooxygenase, antibiotic biosynthesis, heme, iron, metal-binding
Biological source	STREPTOMYCES VENEZUELAE
Total number of polymer chains	2
Total formula weight	98677.68
Authors	Yermalitskaya, L.I.,Kim, Y.,Sherman, D.H.,Waterman, M.R.,Podust, L.M. (deposition date: 2006-01-20, release date: 2007-02-20, Last modification date: 2023-12-13)
Primary citation	Sherman, D.H.,Li, S.,Yermalitskaya, L.V.,Kim, Y.,Smith, J.A.,Waterman, M.R.,Podust, L.M. The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae. J.Biol.Chem., 281:26289-, 2006 Cited by PubMed: 16825192 DOI: 10.1074/JBC.M605478200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation