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6N5D
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BU of 6n5d by Molmil
Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope
Descriptor: Hemagglutinin, antibody heavy chain, antibody light chain
Authors:Bajic, G, Schmidt, A.G.
Deposit date:2018-11-21
Release date:2019-06-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope.
Cell Host Microbe, 25, 2019
5W0D
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BU of 5w0d by Molmil
Inferred precursor (UCA) of the human antibody lineage K03.12 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2017-05-30
Release date:2018-02-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires.
Immunity, 48, 2018
5W08
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BU of 5w08 by Molmil
A/Texas/50/2012(H3N2) Influenza hemagglutinin in complex with K03.12 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2017-05-30
Release date:2018-02-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires.
Immunity, 48, 2018
6XPQ
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BU of 6xpq by Molmil
Human antibody D1 H1-17/H3-14 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
Descriptor: Hemagglutinin, antibody D1 H1-17/H3-14 light chain, antibody D1 H1-17/H3-14 heavy chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-08
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XPX
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BU of 6xpx by Molmil
Human antibody S1V2-51 in complex with the influenza hemagglutinin head domain of A/Aichi/2/1968 (X-31)(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICINE, GLYCEROL, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XPY
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BU of 6xpy by Molmil
Human antibody S1V2-58 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
Descriptor: Fab heavy chain, Fab light chain, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.603 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XQ4
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BU of 6xq4 by Molmil
Human antibody S8V2-47 in complex with the influenza hemagglutinin head domain of A/Beijing/262/1995(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, antibody S8V2-47 heavy chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.347 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XPR
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BU of 6xpr by Molmil
Human antibody D2 H1-1/H3-1 H3 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C, Lee, J.
Deposit date:2020-07-08
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.092 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XPO
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BU of 6xpo by Molmil
Influenza hemagglutinin A/Bangkok/01/1979(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-08
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XPZ
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BU of 6xpz by Molmil
Human antibody S1V2-83 in complex with the influenza hemagglutinin head domain of A/Moscow/10/1999(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XQ0
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BU of 6xq0 by Molmil
Human antibody S8V2-18 in complex with the influenza hemagglutinin head domain of A/California/7/2009(NYMC-X181)(H1N1)
Descriptor: GLYCEROL, Hemagglutinin, antibody S8V2-18 heavy chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
6XQ2
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BU of 6xq2 by Molmil
Human antibody S8V2-37 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2020-07-09
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface.
Mbio, 12, 2021
7CXA
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BU of 7cxa by Molmil
Structure of human Galectin-3 CRD in complex with TD-139 belonging to P31 space group.
Descriptor: 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, CHLORIDE ION, Galectin-3
Authors:Kumar, A.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3.
Glycobiology, 31, 2021
7CXC
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BU of 7cxc by Molmil
Structure of mouse Galectin-3 CRD point mutant (V160A) in complex with TD-139 belonging to P121 space group.
Descriptor: 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, Galectin-3
Authors:Kumar, A.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3.
Glycobiology, 31, 2021
7CXB
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BU of 7cxb by Molmil
Structure of mouse Galectin-3 CRD in complex with TD-139 belonging to P6522 space group.
Descriptor: 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, CHLORIDE ION, Galectin-3
Authors:Kumar, A.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3.
Glycobiology, 31, 2021
8UDG
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BU of 8udg by Molmil
S1V2-72 Fab bound to EHA2 from influenza B/Malaysia/2506/2004
Descriptor: Hemagglutinin, S1V2-72 heavy chain, S1V2-72 light chain
Authors:Finney, J, Kong, S, Walsh Jr, R.M, Harrison, S.C, Kelsoe, G.
Deposit date:2023-09-28
Release date:2023-11-15
Last modified:2024-01-10
Method:ELECTRON MICROSCOPY (4.98 Å)
Cite:Protective human antibodies against a conserved epitope in pre- and postfusion influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 121, 2024
7CXD
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BU of 7cxd by Molmil
Xray structure of rat Galectin-3 CRD in complex with TD-139 belonging to P121 space group
Descriptor: 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, BROMIDE ION, Galectin-3
Authors:Kumar, A.
Deposit date:2020-09-01
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3.
Glycobiology, 31, 2021
6E56
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BU of 6e56 by Molmil
Human antibody H2214 in complex with influenza hemagglutinin A/Aichi/2/1968 (X-31) (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2018-07-19
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
Cell, 177, 2019
6E4X
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BU of 6e4x by Molmil
Human antibody S5V2-29 in complex with influenza hemagglutinin A/Texas/50/2012 (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2018-07-18
Release date:2019-05-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
Cell, 177, 2019
4HL0
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BU of 4hl0 by Molmil
Crystal structure of full-length Toxascaris leonina galectin
Descriptor: galectin
Authors:Jeong, M.S.
Deposit date:2012-10-15
Release date:2013-02-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of full-length Toxascaris leonina galectin with two carbohydrate-recognition domains.
Acta Crystallogr.,Sect.D, 69, 2013
5KG9
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BU of 5kg9 by Molmil
Crystal structure of the gp120 v2 antibody RE505-22 Fab from IGH- and IGK-humanized mouse
Descriptor: Antibody RE505-22 Fab heavy chain, Antibody RE505-22 Fab light chain
Authors:Nicely, N.I.
Deposit date:2016-06-13
Release date:2017-01-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.
J. Immunol., 198, 2017
7UMM
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BU of 7umm by Molmil
H1 Solomon Islands 2006 hemagglutinin in complex with Ab109
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Windsor, I.W, Caradonna, T.M, Schmidt, A.G.
Deposit date:2022-04-07
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:An epitope-enriched immunogen expands responses to a conserved viral site.
Cell Rep, 41, 2022
7TRH
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BU of 7trh by Molmil
Human antibody K03.28 in complex with the influenza hemagglutinin head domain of A/California/07/2009(H1N1)(X-181)
Descriptor: Hemagglutinin, K03.28 Fab heavy chain, K03.28 Fab lambda light chain
Authors:McCarthy, K.R.
Deposit date:2022-01-28
Release date:2023-08-02
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses.
Plos Biol., 21, 2023
7TRI
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BU of 7tri by Molmil
Human antibody S8V1-172 in complex with the influenza hemagglutinin head domain of A/Sydney/05/1997(H3N2)
Descriptor: Hemagglutinin, S8V1-172 Fab heavy chain, S8V1-172 Fab kappa light chain, ...
Authors:McCarthy, K.R.
Deposit date:2022-01-28
Release date:2023-08-02
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:A new class of antibodies that overcomes a steric barrier to cross-group neutralization of influenza viruses.
Plos Biol., 21, 2023
4FQZ
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BU of 4fqz by Molmil
Crystal structure of a protease-resistant mutant form of human galectin-8
Descriptor: 1,2-ETHANEDIOL, Galectin-8, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Yoshida, H, Kamitori, S.
Deposit date:2012-06-26
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structure of a protease-resistant mutant form of human galectin-8 with two carbohydrate recognition domains
Febs J., 279, 2012

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