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2Y20
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BU of 2y20 by Molmil
The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291I mutant
Descriptor: UNCHARACTERIZED PROTEIN, ZINC ION
Authors:Zeth, K, Ferris, H.U, Hulko, M, Lupas, A.N.
Deposit date:2010-12-12
Release date:2011-07-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Mechanisms of Hamp-Mediated Signaling in Transmembrane Receptors.
Structure, 19, 2011
2Y0Q
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BU of 2y0q by Molmil
The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291C mutant
Descriptor: UNCHARACTERIZED PROTEIN
Authors:Zeth, K, Ferris, H.U, Hulko, M, Lupas, A.N.
Deposit date:2010-12-07
Release date:2011-03-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Mechanisms of Hamp-Mediated Signaling in Transmembrane Receptors.
Structure, 19, 2011
2Y21
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BU of 2y21 by Molmil
The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291V mutant
Descriptor: HAMP
Authors:Zeth, K, Ferris, H.U, Hulko, M, Lupas, A.N.
Deposit date:2010-12-12
Release date:2011-03-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The mechanisms of HAMP-mediated signaling in transmembrane receptors.
Structure, 19, 2011
6R60
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BU of 6r60 by Molmil
asymmetric antiparallel assembly of two 5-bladed beta-propeller fragments
Descriptor: WD-40 repeat protein
Authors:Afanasieva, E, Lupas, A.N, Hartmann, M.D.
Deposit date:2019-03-26
Release date:2019-11-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural diversity of oligomeric beta-propellers with different numbers of identical blades.
Elife, 8, 2019
6RCC
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BU of 6rcc by Molmil
Domain C P140 Mycoplasma genitalium
Descriptor: Adhesin P1, CHLORIDE ION, SODIUM ION
Authors:Vizarraga, D, Aparicio, D, Perez, R, Illanes, R, Fita, I.
Deposit date:2019-04-11
Release date:2020-11-04
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Alternative conformation of the C-domain of the P140 protein from Mycoplasma genitalium.
Acta Crystallogr.,Sect.F, 76, 2020
6RCD
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BU of 6rcd by Molmil
Octamer C-Domain P140 Mycoplasma genitalium.
Descriptor: MgPa adhesin
Authors:Vizarraga, D, Aparicio, D, Perez, R, Illanes, R, Fita, I.
Deposit date:2019-04-11
Release date:2020-11-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Alternative conformation of the C-domain of the P140 protein from Mycoplasma genitalium.
Acta Crystallogr.,Sect.F, 76, 2020
9FCH
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BU of 9fch by Molmil
P116 dimer in the full state (PDB structure of the full-length ectodomain truncated to amino acids 246-818)
Descriptor: Uncharacterized protein MG075 homolog
Authors:Mager, S.
Deposit date:2024-05-15
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (6.52 Å)
Cite:P116 from Mycoplasma is a self-sufficient lipid uptake and delivery machinery
To Be Published
6QM8
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BU of 6qm8 by Molmil
Leishmania tarentolae proteasome 20S subunit apo structure
Descriptor: Proteasome alpha1 chain, Proteasome alpha2 chain, Proteasome alpha3 chain, ...
Authors:Rowland, P, Goswami, P.
Deposit date:2019-02-01
Release date:2019-04-17
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc.Natl.Acad.Sci.USA, 116, 2019
6QM7
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BU of 6qm7 by Molmil
Leishmania tarentolae proteasome 20S subunit complexed with GSK3494245
Descriptor: Proteasome alpha1 chain, Proteasome alpha2 chain, Proteasome alpha3 chain, ...
Authors:Rowland, P, Goswami, P.
Deposit date:2019-02-01
Release date:2019-04-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc.Natl.Acad.Sci.USA, 116, 2019
8OLU
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BU of 8olu by Molmil
Leishmania tarentolae proteasome 20S subunit in complex with 1-Benzyl-N-(3-(cyclopropylcarbamoyl)phenyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide
Descriptor: Proteasome alpha 1 subunit, putative, Proteasome alpha 5 subunit, ...
Authors:Rowland, P.
Deposit date:2023-03-30
Release date:2023-08-09
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.
J.Med.Chem., 66, 2023
7OW8
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BU of 7ow8 by Molmil
CryoEM structure of the ABC transporter BmrA E504A mutant in complex with ATP-Mg
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding/permease protein BmrA
Authors:Gobet, A, Schoehn, G, Falson, P, Chaptal, V.
Deposit date:2021-06-17
Release date:2022-01-19
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Sci Adv, 8, 2022
8SYC
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BU of 8syc by Molmil
Crystal structure of PDE3B in complex with GSK4394835A
Descriptor: MAGNESIUM ION, [3-[(4,7-dimethoxyquinolin-2-yl)carbonylamino]-5-[methyl-(phenylmethyl)carbamoyl]phenyl]-oxidanyl-oxidanylidene-boron, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
Authors:Concha, N.O, Nolte, R.
Deposit date:2023-05-25
Release date:2024-02-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library.
J.Med.Chem., 67, 2024
5MVR
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BU of 5mvr by Molmil
Crystal structure of Bacillus subtilus YdiB
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Jault, J.-M, Aghajari, N.
Deposit date:2017-01-17
Release date:2017-09-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.762 Å)
Cite:Expanding the Kinome World: A New Protein Kinase Family Widely Conserved in Bacteria.
J. Mol. Biol., 429, 2017
7BWM
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BU of 7bwm by Molmil
Cryo-EM structure of the human pathogen Mycoplasma pneumoniae P1
Descriptor: Adhesin P1
Authors:Kawamoto, A, Kenri, T, Namba, K, Miyata, M.
Deposit date:2020-04-15
Release date:2020-10-28
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Immunodominant proteins P1 and P40/P90 from human pathogen Mycoplasma pneumoniae.
Nat Commun, 11, 2020
7BG4
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BU of 7bg4 by Molmil
Multidrug resistance transporter BmrA mutant E504A bound with ATP, Mg, and Rhodamine 6G solved by Cryo-EM
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding/permease protein BmrA, ...
Authors:Wiseman, B, Chaptal, V, Zampieri, V, Magnard, S, Hogbom, M, Falson, P.
Deposit date:2021-01-05
Release date:2022-01-12
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Sci Adv, 8, 2022
5NP9
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BU of 5np9 by Molmil
Crystal structure of Bacillus subtilis YdiB in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
Authors:Ballut, L, Aghajari, N.
Deposit date:2017-04-13
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Expanding the Kinome World: A New Protein Kinase Family Widely Conserved in Bacteria.
J. Mol. Biol., 429, 2017
6RJ1
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BU of 6rj1 by Molmil
N-Domain P40/P90 Mycoplasma pneumoniae
Descriptor: Mgp-operon protein 3
Authors:Vizarraga, D, Aparicio, D, Illanes, R, Fita, I.
Deposit date:2019-04-25
Release date:2020-11-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Immunodominant proteins P1 and P40/P90 from human pathogen Mycoplasma pneumoniae.
Nat Commun, 11, 2020
8A9B
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BU of 8a9b by Molmil
Single Particle cryo-EM of the empty lipid binding protein P116 (MPN213) from Mycoplasma pneumoniae at 4 Angstrom resolution
Descriptor: Lipid binding protein P116 (MPN213)
Authors:Sprankel, L, Vizarraga, D.
Deposit date:2022-06-28
Release date:2023-02-22
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Essential protein P116 extracts cholesterol and other indispensable lipids for Mycoplasmas.
Nat.Struct.Mol.Biol., 30, 2023
8A9A
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BU of 8a9a by Molmil
Single Particle cryo-EM of the lipid binding protein P116 (MPN213) from Mycoplasma pneumoniae at 3.3 Angstrom resolution.
Descriptor: Lipid binding protein P116 (MPN213)
Authors:Sprankel, L, Vizarraga, D.
Deposit date:2022-06-28
Release date:2023-02-22
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Essential protein P116 extracts cholesterol and other indispensable lipids for Mycoplasmas.
Nat.Struct.Mol.Biol., 30, 2023
1YFB
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BU of 1yfb by Molmil
The solution structure of the N-domain of the transcription factor abrB
Descriptor: Transition state regulatory protein abrB
Authors:Truffault, V, Djuranovic, S, Coles, M.
Deposit date:2004-12-31
Release date:2005-04-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:AbrB-like transcription factors assume a swapped hairpin fold that is evolutionarily related to double-psi beta barrels.
Structure, 13, 2005
1YSF
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BU of 1ysf by Molmil
The solution structure of the N-domain of the transcription factor abrB
Descriptor: Transition state regulatory protein abrB
Authors:Truffault, V, Djuranovic, S, Coles, M.
Deposit date:2005-02-08
Release date:2005-04-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:AbrB-like transcription factors assume a swapped hairpin fold that is evolutionarily related to double-psi beta barrels.
Structure, 13, 2005
8BPT
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BU of 8bpt by Molmil
Crystal structure of the second bromodomain of BRD5 from Leishmania donovani
Descriptor: Bromo domain-containing protein
Authors:Wilkinson, A.J, Dodson, E.J, Jones, N.G, Borgia, J.
Deposit date:2022-11-17
Release date:2023-09-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery.
Acs Infect Dis., 9, 2023
6DCH
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BU of 6dch by Molmil
Structure of isonitrile biosynthesis enzyme ScoE
Descriptor: ACETATE ION, CHLORIDE ION, CHOLINE ION, ...
Authors:Born, D.A, Drennan, C.L.
Deposit date:2018-05-07
Release date:2018-06-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Isonitrile Formation by a Non-Heme Iron(II)-Dependent Oxidase/Decarboxylase.
Angew. Chem. Int. Ed. Engl., 57, 2018
2M3X
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BU of 2m3x by Molmil
Solution structure of Ph1500: a homohexameric protein centered on a 12-bladed beta-propeller
Descriptor: PH1500
Authors:Varnay, I, Truffault, V, Kessler, H, Coles, M.
Deposit date:2013-01-28
Release date:2014-01-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of Ph1500: a homohexameric protein centered on a 12-bladed beta-propeller
To be Published
4DWN
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BU of 4dwn by Molmil
Crystal Structure of Human BinCARD CARD
Descriptor: Bcl10-interacting CARD protein, SULFATE ION
Authors:Chen, K.-E, Kobe, B, Martin, J.L.
Deposit date:2012-02-26
Release date:2013-02-06
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.581 Å)
Cite:The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized.
Acta Crystallogr.,Sect.D, 69, 2013

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