6HYI
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![BU of 6hyi by Molmil](/molmil-images/mine/6hyi) | Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma cruzi at 1.4 A resolution in complex with inosine | Descriptor: | INOSINE, Protein kinase A regulatory subunit | Authors: | Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. | Deposit date: | 2018-10-22 | Release date: | 2019-11-13 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.39944851 Å) | Cite: | Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens. Elife, 12, 2024
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6HYQ
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6H4G
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![BU of 6h4g by Molmil](/molmil-images/mine/6h4g) | Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei: E311A, T318R, V319A mutant bound to cAMP in the A site | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, INOSINE, Protein kinase A regulatory subunit | Authors: | Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. | Deposit date: | 2018-07-21 | Release date: | 2019-08-14 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.143517 Å) | Cite: | Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens. Elife, 12, 2024
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6IA7
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![BU of 6ia7 by Molmil](/molmil-images/mine/6ia7) | T. brucei IFT22 GTP-bound crystal structure | Descriptor: | CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, Intraflagellar transport protein 22, ... | Authors: | Wachter, S, Basquin, J, Lorentzen, E. | Deposit date: | 2018-11-26 | Release date: | 2019-04-10 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly. Embo J., 38, 2019
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6IAE
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![BU of 6iae by Molmil](/molmil-images/mine/6iae) | T. brucei IFT22 GDP-bound crystal structure | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Intraflagellar transport protein 22, MAGNESIUM ION | Authors: | Wachter, S, Basquin, J, Lorentzen, E. | Deposit date: | 2018-11-26 | Release date: | 2019-04-10 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly. Embo J., 38, 2019
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2WP8
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![BU of 2wp8 by Molmil](/molmil-images/mine/2wp8) | yeast rrp44 nuclease | Descriptor: | CHLORIDE ION, EXOSOME COMPLEX COMPONENT RRP45, EXOSOME COMPLEX COMPONENT SKI6, ... | Authors: | Basquin, J, Bonneau, F, Ebert, J, Lorentzen, E, Conti, E. | Deposit date: | 2009-08-03 | Release date: | 2009-11-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Yeast Exosome Functions as a Macromolecular Cage to Channel RNA Substrates for Degradation. Cell(Cambridge,Mass.), 139, 2009
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2YC2
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2YC4
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![BU of 2yc4 by Molmil](/molmil-images/mine/2yc4) | Intraflagellar Transport Complex 25-27 from Chlamydomonas | Descriptor: | CALCIUM ION, CHLORIDE ION, INTRAFLAGELLAR TRANSPORT PROTEIN 25, ... | Authors: | Bhogaraju, S, Taschner, M, Lorentzen, E. | Deposit date: | 2011-03-11 | Release date: | 2011-03-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Intraflagellar Transport Complex 25/27. Embo J., 30, 2011
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4B5O
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4B5P
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5N4A
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![BU of 5n4a by Molmil](/molmil-images/mine/5n4a) | Crystal structure of Chlamydomonas IFT80 | Descriptor: | GLYCEROL, Intraflagellar transport protein 80, OXALATE ION | Authors: | Taschner, M, Mourao, A. | Deposit date: | 2017-02-10 | Release date: | 2018-02-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis. Elife, 7, 2018
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2R94
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![BU of 2r94 by Molmil](/molmil-images/mine/2r94) | Crystal Structure of KD(P)GA from T.tenax | Descriptor: | 2-Keto-3-deoxy-(6-phospho-)gluconate aldolase, PYRUVIC ACID | Authors: | Pauluhn, A, Pohl, E. | Deposit date: | 2007-09-12 | Release date: | 2008-03-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax. Proteins, 72, 2008
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7Q3E
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![BU of 7q3e by Molmil](/molmil-images/mine/7q3e) | Structure of the mouse CPLANE-RSG1 complex | Descriptor: | Ciliogenesis and planar polarity effector 2, GUANOSINE-5'-TRIPHOSPHATE, Protein fuzzy homolog, ... | Authors: | Langousis, G, Cavadini, S, Kempf, G, Matthias, P. | Deposit date: | 2021-10-27 | Release date: | 2022-04-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structure of the ciliogenesis-associated CPLANE complex. Sci Adv, 8, 2022
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7Q3D
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![BU of 7q3d by Molmil](/molmil-images/mine/7q3d) | Structure of the human CPLANE complex | Descriptor: | Protein fuzzy homolog, Protein inturned, WD repeat-containing and planar cell polarity effector protein fritz homolog | Authors: | Langousis, G, Cavadini, S, Kempf, G, Matthias, P. | Deposit date: | 2021-10-27 | Release date: | 2022-04-06 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Structure of the ciliogenesis-associated CPLANE complex. Sci Adv, 8, 2022
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4LVR
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![BU of 4lvr by Molmil](/molmil-images/mine/4lvr) | Crystal structure of IFT81 N-terminal domain | Descriptor: | Intraflagellar transport protein 81 | Authors: | Bhogaraju, S. | Deposit date: | 2013-07-26 | Release date: | 2013-09-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81. Science, 341, 2013
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4LVP
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![BU of 4lvp by Molmil](/molmil-images/mine/4lvp) | Crystal structure of IFT81 N-terminal domain | Descriptor: | Intraflagellar transport protein 81, Tantalum | Authors: | Bhogaraju, S. | Deposit date: | 2013-07-26 | Release date: | 2013-09-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.323 Å) | Cite: | Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81. Science, 341, 2013
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7OGG
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![BU of 7ogg by Molmil](/molmil-images/mine/7ogg) | Nse5/6 complex | Descriptor: | DNA repair protein KRE29,DNA repair protein KRE29,DNA repair protein KRE29, Non-structural maintenance of chromosome element 5,Non-structural maintenance of chromosome element 5,Non-structural maintenance of chromosome element 5 | Authors: | Basquin, J, Taschner, M, Gruber, S. | Deposit date: | 2021-05-06 | Release date: | 2021-07-07 | Last modified: | 2021-08-11 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding. Embo J., 40, 2021
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