8I7W
| Cryo-EM structure of GSK256073 bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer | Descriptor: | 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Park, J.H, Ishimoto, N, Park, S.Y. | Deposit date: | 2023-02-02 | Release date: | 2024-02-07 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2. Nat Commun, 14, 2023
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8I7V
| Cryo-EM structure of Acipimox bound human hydroxy-carboxylic acid receptor 2 in complex with Gi heterotrimer | Descriptor: | 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Park, J.H, Ishimoto, N, Park, S.Y. | Deposit date: | 2023-02-02 | Release date: | 2024-02-07 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structural basis for ligand recognition and signaling of hydroxy-carboxylic acid receptor 2. Nat Commun, 14, 2023
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7WF7
| Cryo-EM of Sphingosine 1-phosphate receptor 1 / Gi complex bound to S1P | Descriptor: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | He, Y, Xu, Z. | Deposit date: | 2021-12-26 | Release date: | 2022-01-05 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of sphingosine-1-phosphate receptor 1 activation and biased agonism. Nat.Chem.Biol., 18, 2022
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