5F2V
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![BU of 5f2v by Molmil](/molmil-images/mine/5f2v) | Crystal structure of the small alarmone synthethase 1 from Bacillus subtilis bound to AMPCPP | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, GTP pyrophosphokinase YjbM, MAGNESIUM ION | Authors: | Steinchen, W, Schuhmacher, J.S, Altegoer, F, Bange, G. | Deposit date: | 2015-12-02 | Release date: | 2015-12-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone. Proc.Natl.Acad.Sci.USA, 112, 2015
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6TWJ
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6TWM
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![BU of 6twm by Molmil](/molmil-images/mine/6twm) | Product bound structure of the Ectoine utilization protein EutE (DoeB) from Ruegeria pomeroyi | Descriptor: | 2,4-DIAMINOBUTYRIC ACID, ACETATE ION, N-acetyl-L-2,4-diaminobutyric acid deacetylase, ... | Authors: | Mais, C.-N, Altegoer, F, Bange, G. | Deposit date: | 2020-01-13 | Release date: | 2020-05-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex. J.Biol.Chem., 295, 2020
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6TWK
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![BU of 6twk by Molmil](/molmil-images/mine/6twk) | Substrate bound structure of the Ectoine utilization protein EutD (DoeA) from Halomonas elongata | Descriptor: | (2~{R})-4-azanyl-2-[[(1~{S})-1-oxidanylethyl]amino]butanoic acid, (4S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Ectoine hydrolase DoeA | Authors: | Mais, C.-N, Altegoer, F, Bange, G. | Deposit date: | 2020-01-13 | Release date: | 2020-05-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex. J.Biol.Chem., 295, 2020
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6TWL
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6FGJ
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![BU of 6fgj by Molmil](/molmil-images/mine/6fgj) | Crystal structure of the small alarmone synthethase 2 from Staphylococcus aureus | Descriptor: | GTP pyrophosphokinase, TRIETHYLENE GLYCOL | Authors: | Bange, G, Steinchen, W, Vogt, M, Altegoer, F. | Deposit date: | 2018-01-11 | Release date: | 2018-02-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | Structural and mechanistic divergence of the small (p)ppGpp synthetases RelP and RelQ. Sci Rep, 8, 2018
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6FGX
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![BU of 6fgx by Molmil](/molmil-images/mine/6fgx) | Crystal structure of the small alarmone synthethase 2 from Staphylococcus aureus bound to AMPCPP | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, GTP pyrophosphokinase, MAGNESIUM ION | Authors: | Bange, G, Vogt, M, Steinchen, W, Altegoer, F. | Deposit date: | 2018-01-11 | Release date: | 2018-02-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and mechanistic divergence of the small (p)ppGpp synthetases RelP and RelQ. Sci Rep, 8, 2018
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6FGK
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5NLA
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5O6U
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![BU of 5o6u by Molmil](/molmil-images/mine/5o6u) | Structure of the Cascade-I-Fv R-loop complex from Shewanella putrefaciens | Descriptor: | CRISPR-associated protein, Csy4 family, Uncharacterized protein, ... | Authors: | Pausch, P, Altegoer, F, Bange, G. | Deposit date: | 2017-06-07 | Release date: | 2017-08-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance. Mol. Cell, 67, 2017
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5O7H
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![BU of 5o7h by Molmil](/molmil-images/mine/5o7h) | Structure of the Cascade-I-Fv complex from Shewanella putrefaciens | Descriptor: | CRISPR-associated protein, Csy4 family, Cas5fv, ... | Authors: | Pausch, P, Altegoer, F, Bange, G. | Deposit date: | 2017-06-08 | Release date: | 2017-08-16 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance. Mol. Cell, 67, 2017
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6EN7
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5JIG
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![BU of 5jig by Molmil](/molmil-images/mine/5jig) | Crytsal structure of Wss1 from S. pombe | Descriptor: | NICKEL (II) ION, OXYGEN MOLECULE, Ubiquitin and WLM domain-containing metalloprotease SPCC1442.07c | Authors: | Groll, M, Stingele, J, Boulton, S. | Deposit date: | 2016-04-22 | Release date: | 2016-11-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN. Mol.Cell, 64, 2016
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5LN5
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4RZ2
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4RZ3
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![BU of 4rz3 by Molmil](/molmil-images/mine/4rz3) | Crystal structure of the MinD-like ATPase FlhG | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Site-determining protein | Authors: | Schuhmacher, J.S, Bange, G. | Deposit date: | 2014-12-18 | Release date: | 2015-03-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | MinD-like ATPase FlhG effects location and number of bacterial flagella during C-ring assembly. Proc.Natl.Acad.Sci.USA, 112, 2015
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7UPY
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![BU of 7upy by Molmil](/molmil-images/mine/7upy) | An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F. | Deposit date: | 2022-04-18 | Release date: | 2022-08-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022
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7UPX
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![BU of 7upx by Molmil](/molmil-images/mine/7upx) | Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, SP1-77 Fab heavy chain, SP1-77 Fab light chain, ... | Authors: | Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F. | Deposit date: | 2022-04-18 | Release date: | 2022-08-10 | Last modified: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022
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7UPW
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![BU of 7upw by Molmil](/molmil-images/mine/7upw) | Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F. | Deposit date: | 2022-04-18 | Release date: | 2022-08-10 | Last modified: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022
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6B8A
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![BU of 6b8a by Molmil](/molmil-images/mine/6b8a) | Crystal structure of MvfR ligand binding domain in complex with M64 | Descriptor: | 2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide, COBALT HEXAMMINE(III), DNA-binding transcriptional regulator | Authors: | Kitao, T, Steinbacher, S, Maskos, K, Blaesse, M, Rahme, L.G. | Deposit date: | 2017-10-05 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Molecular Insights into Function and Competitive Inhibition ofPseudomonas aeruginosaMultiple Virulence Factor Regulator. MBio, 9, 2018
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5DEC
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4ZN4
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6G15
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![BU of 6g15 by Molmil](/molmil-images/mine/6g15) | Crystal structure of pppGpp bound RbgA from S. aureus | Descriptor: | Ribosome biogenesis GTPase A, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate) | Authors: | Pausch, P, Bange, G. | Deposit date: | 2018-03-20 | Release date: | 2018-11-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for (p)ppGpp-mediated inhibition of the GTPase RbgA. J. Biol. Chem., 293, 2018
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6G0Z
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![BU of 6g0z by Molmil](/molmil-images/mine/6g0z) | Crystal structure of GDP bound RbgA from S. aureus | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Ribosome biogenesis GTPase A | Authors: | Pausch, P, Bange, G. | Deposit date: | 2018-03-20 | Release date: | 2018-11-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for (p)ppGpp-mediated inhibition of the GTPase RbgA. J. Biol. Chem., 293, 2018
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6G12
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![BU of 6g12 by Molmil](/molmil-images/mine/6g12) | Crystal structure of GMPPNP bound RbgA from S. aureus | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ribosome biogenesis GTPase A | Authors: | Pausch, P, Bange, G. | Deposit date: | 2018-03-20 | Release date: | 2018-11-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.929 Å) | Cite: | Structural basis for (p)ppGpp-mediated inhibition of the GTPase RbgA. J. Biol. Chem., 293, 2018
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