6N5D
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![BU of 6n5d by Molmil](/molmil-images/mine/6n5d) | |
5T6L
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![BU of 5t6l by Molmil](/molmil-images/mine/5t6l) | Crystal structure of 10E8 Fab in complex with the MPER epitope scaffold T117v2 | Descriptor: | 10E8 EPITOPE SCAFFOLD T117V2, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Antibody 10E8 FAB HEAVY CHAIN, ... | Authors: | Irimia, A, Wilson, I.A. | Deposit date: | 2016-09-01 | Release date: | 2017-03-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design. PLoS Pathog., 13, 2017
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5TFW
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![BU of 5tfw by Molmil](/molmil-images/mine/5tfw) | Crystal structure of 10E8 Fab light chain mutant2 against the MPER region of the HIV-1 Env, in complex with T117v2 epitope scaffold | Descriptor: | 1,2-ETHANEDIOL, 10E8 EPITOPE SCAFFOLD T117V2, Antibody 10E8 FAB HEAVY CHAIN, ... | Authors: | Irimia, A, Wilson, I.A. | Deposit date: | 2016-09-26 | Release date: | 2017-03-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.168 Å) | Cite: | Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design. PLoS Pathog., 13, 2017
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5T80
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5T85
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![BU of 5t85 by Molmil](/molmil-images/mine/5t85) | |
8F9M
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![BU of 8f9m by Molmil](/molmil-images/mine/8f9m) | |
8F92
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![BU of 8f92 by Molmil](/molmil-images/mine/8f92) | HIV Env BG505_MD39_B11 SOSIP boosting trimer in complex with B11_d77.7 mouse Fab and RM20A3 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B11_d77.7 Fab heavy chain, ... | Authors: | Torres, J.L, Ozorowski, G, Ward, A.B. | Deposit date: | 2022-11-23 | Release date: | 2024-05-15 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies. Science, 384, 2024
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8F9G
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![BU of 8f9g by Molmil](/molmil-images/mine/8f9g) | HIV Env germline targeting BG505_MD64_N332-GT5 SOSIP in complex with V3-glycan polyclonal Fab isolated from immunized BG18HCgl knock-in mice | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505_MD64_N332-GT5 gp120, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2022-11-23 | Release date: | 2024-05-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies. Science, 384, 2024
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6NF5
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![BU of 6nf5 by Molmil](/molmil-images/mine/6nf5) | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP1 fragment antigen binding heavy chain, ... | Authors: | Ozorowski, G, Torres, J.L, Steichen, J.M, Schief, W.R, Ward, A.B. | Deposit date: | 2018-12-18 | Release date: | 2019-11-06 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science, 366, 2019
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6NFC
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![BU of 6nfc by Molmil](/molmil-images/mine/6nfc) | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP42 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP42 fragment antigen binding heavy chain, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2018-12-19 | Release date: | 2019-11-06 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science, 366, 2019
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8V2E
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8U08
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![BU of 8u08 by Molmil](/molmil-images/mine/8u08) | |
8U03
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![BU of 8u03 by Molmil](/molmil-images/mine/8u03) | |
8TZW
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![BU of 8tzw by Molmil](/molmil-images/mine/8tzw) | |
8TZN
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![BU of 8tzn by Molmil](/molmil-images/mine/8tzn) | |
8VFV
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![BU of 8vfv by Molmil](/molmil-images/mine/8vfv) | HIV Env BG505_MD39_B16 SOSIP boosting trimer in complex with B16_d77.5 mouse Fab and RM20A3 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B16_d77.5 mouse Fab heavy chain Fv, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2023-12-22 | Release date: | 2024-05-15 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies. Science, 384, 2024
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