4EKU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eku by Molmil](/molmil-images/mine/4eku) | |
4DZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4dzd by Molmil](/molmil-images/mine/4dzd) | |
2B5F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b5f by Molmil](/molmil-images/mine/2b5f) | Crystal structure of the spinach aquaporin SoPIP2;1 in an open conformation to 3.9 resolution | Descriptor: | aquaporin | Authors: | Tornroth-Horsefield, S, Wang, Y, Hedfalk, K, Johanson, U, Karlsson, M, Tajkhorshid, E, Neutze, R, Kjellbom, P. | Deposit date: | 2005-09-28 | Release date: | 2005-12-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural mechanism of plant aquaporin gating Nature, 439, 2006
|
|
4DRQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4drq by Molmil](/molmil-images/mine/4drq) | Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-1-((S)-1-(3,5-dichlorophenylsulfonyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxy -phenyl)propyl)phenoxy)acetic acid | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP5, {3-[(1S)-1-[({(2S)-1-[(3,5-dichlorophenyl)sulfonyl]piperidin-2-yl}carbonyl)oxy]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid | Authors: | Gopalakrishnan, R, Kozany, C, Wang, Y, Hoogeland, B, Bracher, A, Hausch, F, Schneider, S. | Deposit date: | 2012-02-17 | Release date: | 2012-04-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52. J.Med.Chem., 55, 2012
|
|
1ZUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zub by Molmil](/molmil-images/mine/1zub) | Solution Structure of the RIM1alpha PDZ Domain in Complex with an ELKS1b C-terminal Peptide | Descriptor: | ELKS1b, Regulating synaptic membrane exocytosis protein 1 | Authors: | Lu, J, Li, H, Wang, Y, Sudhof, T.C, Rizo, J. | Deposit date: | 2005-05-30 | Release date: | 2005-08-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of the RIM1alpha PDZ Domain in Complex with an ELKS1b C-terminal Peptide J.Mol.Biol., 352, 2005
|
|
1ZLM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zlm by Molmil](/molmil-images/mine/1zlm) | Crystal structure of the SH3 domain of human osteoclast stimulating factor | Descriptor: | Osteoclast stimulating factor 1 | Authors: | Chen, L, Wang, Y, Wells, D, Toh, D, Harold, H, Zhou, J, DiGiammarino, E, Meehan, E.J. | Deposit date: | 2005-05-06 | Release date: | 2006-05-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.07 Å) | Cite: | Structure of the SH3 domain of human osteoclast-stimulating factor at atomic resolution. Acta Crystallogr.,Sect.F, 62, 2006
|
|
4JKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jkr by Molmil](/molmil-images/mine/4jkr) | Crystal Structure of E. coli RNA Polymerase in complex with ppGpp | Descriptor: | DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA', DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zuo, Y, Wang, Y, Steitz, T.A. | Deposit date: | 2013-03-11 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex. Mol.Cell, 50, 2013
|
|
2CPU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cpu by Molmil](/molmil-images/mine/2cpu) | SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT | Descriptor: | ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION | Authors: | Brayer, G.D, Sidhu, G, Maurus, R, Rydberg, E.H, Braun, C, Wang, Y, Nguyen, N.T, Overall, C.M, Withers, S.G. | Deposit date: | 1999-06-08 | Release date: | 2001-06-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques. Biochemistry, 39, 2000
|
|
4NAD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nad by Molmil](/molmil-images/mine/4nad) | |
2F0X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2f0x by Molmil](/molmil-images/mine/2f0x) | Crystal structure and function of human thioesterase superfamily member 2(THEM2) | Descriptor: | SULFATE ION, Thioesterase superfamily member 2 | Authors: | Cheng, Z, Song, F, Shan, X, Wang, Y, Wei, Z, Gong, W. | Deposit date: | 2005-11-14 | Release date: | 2006-10-10 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of human thioesterase superfamily member 2 Biochem.Biophys.Res.Commun., 349, 2006
|
|
4NAC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nac by Molmil](/molmil-images/mine/4nac) | |
1X6L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x6l by Molmil](/molmil-images/mine/1x6l) | Crystal structure of S. marcescens chitinase A mutant W167A | Descriptor: | Chitinase A | Authors: | Aronson Jr, N.N, Halloran, B.A, Alexyev, M.F, Zhou, X.E, Wang, Y, Meehan, E.J, Chen, L. | Deposit date: | 2004-08-11 | Release date: | 2005-07-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mutation of Trp167 at the -3 subsite of the chitin-binding cleft of S. marcescens chitinase A caused enhanced transglycosylation To be Published
|
|
4EYR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eyr by Molmil](/molmil-images/mine/4eyr) | Crystal structure of multidrug-resistant clinical isolate 769 HIV-1 protease in complex with ritonavir | Descriptor: | HIV-1 PROTEASE, RITONAVIR | Authors: | Liu, Z, Yedidi, R.S, Wang, Y, Brunzelle, J.S, Kovari, I.A, Kovari, L.C. | Deposit date: | 2012-05-01 | Release date: | 2013-01-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Insights into the mechanism of drug resistance: X-ray structure analysis of multi-drug resistant HIV-1 protease ritonavir complex. Biochem.Biophys.Res.Commun., 431, 2013
|
|
6IFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ifu by Molmil](/molmil-images/mine/6ifu) | Cryo-EM structure of type III-A Csm-CTR2-dsDNA complex | Descriptor: | CTR2, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | Authors: | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | Deposit date: | 2018-09-21 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
|
|
6IFR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ifr by Molmil](/molmil-images/mine/6ifr) | Type III-A Csm complex, Cryo-EM structure of Csm-NTR, ATP bound | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Type III-A CRISPR-associated RAMP protein Csm3, ... | Authors: | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | Deposit date: | 2018-09-21 | Release date: | 2018-12-12 | Last modified: | 2019-01-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
|
|
6IFK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ifk by Molmil](/molmil-images/mine/6ifk) | Cryo-EM structure of type III-A Csm-CTR1 complex, AMPPNP bound | Descriptor: | CTR1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | Deposit date: | 2018-09-20 | Release date: | 2018-12-12 | Last modified: | 2019-01-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
|
|
6IG0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ig0 by Molmil](/molmil-images/mine/6ig0) | Type III-A Csm complex, Cryo-EM structure of Csm-CTR1, ATP bound | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CTR1, MAGNESIUM ION, ... | Authors: | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | Deposit date: | 2018-09-21 | Release date: | 2018-12-12 | Last modified: | 2019-01-23 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
|
|
3CIY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ciy by Molmil](/molmil-images/mine/3ciy) | Mouse Toll-like receptor 3 ectodomain complexed with double-stranded RNA | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Liu, L, Botos, I, Wang, Y, Leonard, J.N, Shiloach, J, Segal, D.M, Davies, D.R. | Deposit date: | 2008-03-12 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.41 Å) | Cite: | Structural basis of toll-like receptor 3 signaling with double-stranded RNA. Science, 320, 2008
|
|
7LMB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lmb by Molmil](/molmil-images/mine/7lmb) | Tetrahymena telomerase T5D5 structure at 3.8 Angstrom | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. | Deposit date: | 2021-02-05 | Release date: | 2021-05-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
|
|
6IFY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ify by Molmil](/molmil-images/mine/6ify) | Type III-A Csm complex, Cryo-EM structure of Csm-CTR1 | Descriptor: | CTR1, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | Authors: | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | Deposit date: | 2018-09-21 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
|
|
6IFL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ifl by Molmil](/molmil-images/mine/6ifl) | Cryo-EM structure of type III-A Csm-NTR complex | Descriptor: | NTR, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | Authors: | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | Deposit date: | 2018-09-20 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
|
|
3CPU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cpu by Molmil](/molmil-images/mine/3cpu) | SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT | Descriptor: | CALCIUM ION, CHLORIDE ION, Pancreatic alpha-amylase, ... | Authors: | Brayer, G.D, Sidhu, G, Maurus, R, Rydberg, E.H, Braun, C, Wang, Y, Nguyen, N.T, Overall, C.M, Withers, S.G. | Deposit date: | 1999-06-08 | Release date: | 2001-06-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques. Biochemistry, 39, 2000
|
|
6IFZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ifz by Molmil](/molmil-images/mine/6ifz) | Type III-A Csm complex, Cryo-EM structure of Csm-CTR2-ssDNA complex | Descriptor: | CTR2, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | Authors: | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | Deposit date: | 2018-09-21 | Release date: | 2018-12-12 | Last modified: | 2019-01-23 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
|
|
6IFN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ifn by Molmil](/molmil-images/mine/6ifn) | Crystal structure of Type III-A CRISPR Csm complex | Descriptor: | MANGANESE (II) ION, RNA (32-MER), Type III-A CRISPR-associated RAMP protein Csm3, ... | Authors: | You, L, Wang, J, Wang, Y. | Deposit date: | 2018-09-20 | Release date: | 2018-12-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
|
|
7LMA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lma by Molmil](/molmil-images/mine/7lma) | Tetrahymena telomerase T3D2 structure at 3.3 Angstrom | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | Authors: | He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J. | Deposit date: | 2021-02-05 | Release date: | 2021-05-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of telomerase at several steps of telomere repeat synthesis. Nature, 593, 2021
|
|