7O60
| Crystal structure of human myelin protein P2 at room temperature from joint X-ray and neutron refinement. | Descriptor: | CITRIC ACID, Myelin P2 protein, PALMITIC ACID | Authors: | Laulumaa, S, Blakeley, M.P, Kursula, P. | Deposit date: | 2021-04-09 | Release date: | 2021-09-01 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION | Cite: | Human myelin protein P2: from crystallography to time-lapse membrane imaging and neuropathy-associated variants. Febs J., 288, 2021
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7B2G
| Crystal structure of R120Q GDAP1 mutant | Descriptor: | GLYCEROL, Ganglioside-induced differentiation-associated protein 1 | Authors: | Nguyen, G.T.T, Sutinen, A, Kursula, P. | Deposit date: | 2020-11-26 | Release date: | 2021-12-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability. Plos One, 18, 2023
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7Q6K
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7Q6J
| Crystal structure of the human GDAP1 CMT2 mutant-H123R | Descriptor: | DI(HYDROXYETHYL)ETHER, Ganglioside-induced differentiation-associated protein 1 | Authors: | Sutinen, A, Kursula, P. | Deposit date: | 2021-11-08 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into Charcot-Marie-Tooth disease-linked mutations in human GDAP1. Febs Open Bio, 12, 2022
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6EW4
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6EW2
| Human myelin protein P2 F57A mutant, tetragonal crystal form | Descriptor: | CHLORIDE ION, Myelin P2 protein, PALMITIC ACID | Authors: | Laulumaa, S, Lehtimaki, M, Kursula, P. | Deposit date: | 2017-11-03 | Release date: | 2018-07-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.588 Å) | Cite: | Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the beta barrel in fatty acid binding proteins. BMC Struct. Biol., 18, 2018
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6EW5
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4MGX
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4M9P
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7YWD
| Human GDAP1 core domain, trigonal crystal form | Descriptor: | Ganglioside-induced differentiation-associated protein 1 | Authors: | Raasakka, A, Kursula, P. | Deposit date: | 2022-02-13 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural insights into Charcot-Marie-Tooth disease-linked mutations in human GDAP1. Febs Open Bio, 12, 2022
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8A4J
| Human GDAP1, A247V mutant | Descriptor: | Ganglioside-induced differentiation-associated protein 1 | Authors: | Sutinen, A, Kursula, P. | Deposit date: | 2022-06-12 | Release date: | 2023-04-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability. Plos One, 18, 2023
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8A4K
| Human GDAP1, R282H mutant | Descriptor: | Ganglioside-induced differentiation-associated protein 1 | Authors: | Sutinen, A, Kursula, P. | Deposit date: | 2022-06-12 | Release date: | 2023-04-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability. Plos One, 18, 2023
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5OVC
| PDZ domain from rat Shank3 bound to the C terminus of GKAP | Descriptor: | CHLORIDE ION, GKAP C terminus, synthetic peptide, ... | Authors: | Ponna, S.K, Myllykoski, M, Boeckers, T.M, Kursula, P. | Deposit date: | 2017-08-28 | Release date: | 2018-03-07 | Last modified: | 2018-07-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3. J. Neurochem., 145, 2018
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5OVA
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5OVP
| PDZ domain from rat Shank3 bound to the C terminus of CIRL | Descriptor: | Adhesion G protein-coupled receptor L1, SH3 and multiple ankyrin repeat domains protein 3 | Authors: | Ponna, S.K, Myllykoski, M, Boeckers, T.M, Kursula, P. | Deposit date: | 2017-08-29 | Release date: | 2018-03-07 | Last modified: | 2018-07-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3. J. Neurochem., 145, 2018
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5OVV
| PDZ domain from rat Shank3 bound to the C terminus of ProSAPiP1 | Descriptor: | Leucine zipper putative tumor suppressor 3, SH3 and multiple ankyrin repeat domains protein 3, THIOCYANATE ION | Authors: | Ponna, S.K, Myllykoski, M, Boeckers, T.M, Kursula, P. | Deposit date: | 2017-08-29 | Release date: | 2018-03-07 | Last modified: | 2018-07-11 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3. J. Neurochem., 145, 2018
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