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5TVZ
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BU of 5tvz by Molmil
Solution NMR structure of Saccharomyces cerevisiae Pom152 Ig-like repeat, residues 718-820
Descriptor: Nucleoporin POM152
Authors:Dutta, K, Sampathkumar, P, Cowburn, D, Almo, S.C, Rout, M.P, Fernandez-Martinez, J.
Deposit date:2016-11-10
Release date:2017-02-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.
Structure, 25, 2017
5LPV
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BU of 5lpv by Molmil
Crystal structure of the BRI1 kinase domain (865-1160) in complex with AMPPNP and Mn from Arabidopsis thaliana
Descriptor: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein BRASSINOSTEROID INSENSITIVE 1
Authors:Bojar, D, Martinez, J, Hothorn, M.
Deposit date:2016-08-15
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of the phosphorylated BRI1 kinase domain and implications for brassinosteroid signal initiation.
TO BE PUBLISHED
6ZK7
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BU of 6zk7 by Molmil
Crystal Structure of human PYROXD1/FAD complex
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1
Authors:Meinhart, A, Asanovic, I, Martinez, J, Clausen, T.
Deposit date:2020-06-30
Release date:2021-05-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The oxidoreductase PYROXD1 uses NAD(P) + as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.
Mol.Cell, 81, 2021
5C9F
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BU of 5c9f by Molmil
Crystal structure of a retropepsin-like aspartic protease from Rickettsia conorii
Descriptor: ApRick protease, CHLORIDE ION, SODIUM ION
Authors:Li, M, Gustchina, A, Cruz, R, Simoes, M, Curto, P, Martinez, J, Faro, C, Simoes, I, Wlodawer, A.
Deposit date:2015-06-26
Release date:2015-10-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of RC1339/APRc from Rickettsia conorii, a retropepsin-like aspartic protease.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
5C9B
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BU of 5c9b by Molmil
Crystal structure of a retropepsin-like aspartic protease from Rickettsia conorii
Descriptor: ApRick protease
Authors:Li, M, Gustchina, A, Cruz, R, Simoes, M, Curto, P, Martinez, J, Faro, C, Simoes, I, Wlodawer, A.
Deposit date:2015-06-26
Release date:2015-10-14
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of RC1339/APRc from Rickettsia conorii, a retropepsin-like aspartic protease.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
5C9D
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BU of 5c9d by Molmil
Crystal structure of a retropepsin-like aspartic protease from Rickettsia conorii
Descriptor: ApRick protease, SODIUM ION
Authors:Li, M, Gustchina, A, Cruz, R, Simoes, M, Curto, P, Martinez, J, Faro, C, Simoes, I, Wlodawer, A.
Deposit date:2015-06-26
Release date:2015-10-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure of RC1339/APRc from Rickettsia conorii, a retropepsin-like aspartic protease
Acta Crystallogr.,Sect.D, 71, 2015
3OG9
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BU of 3og9 by Molmil
Structure of YahD with Malic acid
Descriptor: D-MALATE, protein yahD a copper inducible hydrolase
Authors:Martinez Font, J, Mancini, S, Tauberger, E, Moniot, S.
Deposit date:2010-08-16
Release date:2010-12-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Regulation and structure of YahD, a copper inducible alpha/beta hydrolase of Lactococcus lactis IL1403
Fems Microbiol.Lett., 314, 2011
4IFQ
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BU of 4ifq by Molmil
Crystal structure of Saccharomyces cerevisiae NUP192, residues 2 to 960 [ScNup192(2-960)]
Descriptor: IODIDE ION, Nucleoporin NUP192, SULFATE ION
Authors:Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
Deposit date:2012-12-14
Release date:2013-02-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex.
Structure, 21, 2013
7ZTZ
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BU of 7ztz by Molmil
Crystal structure of mutant AR-LBD (Y764C) bound to dihydrotestosterone
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, IMIDAZOLE, ...
Authors:Alegre-Marti, A, Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
Deposit date:2022-05-11
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
Sci Adv, 9, 2023
7ZTX
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BU of 7ztx by Molmil
Crystal structure of mutant AR-LBD (F755V) bound to dihydrotestosterone
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, IMIDAZOLE, ...
Authors:Alegre-Marti, A, Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
Deposit date:2022-05-11
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
Sci Adv, 9, 2023
7ZTV
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BU of 7ztv by Molmil
Crystal structure of mutant AR-LBD (F755L) bound to dihydrotestosterone
Descriptor: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor
Authors:Alegre-Marti, A, Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
Deposit date:2022-05-11
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
Sci Adv, 9, 2023
7ZU2
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BU of 7zu2 by Molmil
Crystal structure of mutant AR-LBD (Q799E) bound to dihydrotestosterone
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, IMIDAZOLE
Authors:Alegre-Marti, A, Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
Deposit date:2022-05-11
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
Sci Adv, 9, 2023
7ZU1
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BU of 7zu1 by Molmil
Crystal structure of mutant AR-LBD (V758A) bound to dihydrotestosterone
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ...
Authors:Alegre-Marti, A, Jimenez-Panizo, A, Estebanez-Perpina, E, Fuentes-Prior, P.
Deposit date:2022-05-11
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
Sci Adv, 9, 2023
3NF5
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BU of 3nf5 by Molmil
Crystal structure of the C-terminal domain of nuclear pore complex component NUP116 from Candida glabrata
Descriptor: GLYCEROL, Nucleoporin NUP116
Authors:Sampathkumar, P, Manglicmot, D, Bain, K, Gilmore, J, Gheyi, T, Rout, M, Sali, A, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-06-09
Release date:2010-08-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata.
Proteins, 80, 2012
7N9F
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BU of 7n9f by Molmil
Structure of the in situ yeast NPC
Descriptor: Dynein light chain 1, cytoplasmic, Nucleoporin 145c, ...
Authors:Villa, E, Singh, D, Ludtke, S.J, Akey, C.W, Rout, M.P, Echeverria, I, Suslov, S.
Deposit date:2021-06-17
Release date:2022-01-26
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (37 Å)
Cite:Comprehensive structure and functional adaptations of the yeast nuclear pore complex.
Cell, 185, 2022
1QKW
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BU of 1qkw by Molmil
Alpha-spectrin Src Homology 3 domain, N47G mutant in the distal loop.
Descriptor: ALPHA II SPECTRIN, GLYCEROL, SULFATE ION
Authors:Vega, M.C, Martinez, J, Serrano, L.
Deposit date:1999-08-16
Release date:2000-08-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Thermodynamic and structural characterization of Asn and Ala residues in the disallowed II' region of the Ramachandran plot.
Protein Sci., 9, 2000
1QKX
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BU of 1qkx by Molmil
Alpha-spectrin Src Homology 3 domain, N47A mutant in the distal loop.
Descriptor: SPECTRIN ALPHA CHAIN
Authors:Vega, M.C, Martinez, J, Serrano, L.
Deposit date:1999-08-16
Release date:2000-12-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Thermodynamic and structural characterization of Asn and Ala residues in the disallowed II' region of the Ramachandran plot.
Protein Sci., 9, 2000
5DPX
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BU of 5dpx by Molmil
1,2,4-Triazole-3-thione compounds as inhibitors of L1, di-zinc metallo-beta-lactamases.
Descriptor: 5-(2-methylphenyl)-3H-1,2,4-triazole-3-thione, Metallo-beta-lactamase L1 type 3, SULFATE ION, ...
Authors:Nauton, L, Garau, G, Khan, R, Dideberg, O.
Deposit date:2015-09-14
Release date:2017-01-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-beta-lactamases.
ChemMedChem, 12, 2017
7P3A
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BU of 7p3a by Molmil
N-terminal domain of CGI-99
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ISOPROPYL ALCOHOL, ...
Authors:Kroupova, A, Jinek, M.
Deposit date:2021-07-07
Release date:2021-12-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular architecture of the human tRNA ligase complex.
Elife, 10, 2021
7P3B
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BU of 7p3b by Molmil
Human RNA ligase RTCB in complex with GMP and Co(II)
Descriptor: ACETATE ION, COBALT (II) ION, FORMIC ACID, ...
Authors:Kroupova, A, Ackle, F, Jinek, M.
Deposit date:2021-07-07
Release date:2021-12-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular architecture of the human tRNA ligase complex.
Elife, 10, 2021
4JMO
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BU of 4jmo by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)-4-methoxybenzenesulfonamide
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-14
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
4L5M
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BU of 4l5m by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH6.5
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide, PHOSPHATE ION
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-06-11
Release date:2013-10-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors.
J.Med.Chem., 56, 2013
4JWL
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BU of 4jwl by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH7.5
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-27
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
4JXH
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BU of 4jxh by Molmil
Complexe of ARNO Sec7 domain with the protein-protein interaction inhibitor N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide at pH 8.5
Descriptor: Cytohesin-2, N-(4-hydroxy-2,6-dimethylphenyl)benzenesulfonamide, PHOSPHATE ION
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-28
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013
4JMI
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BU of 4jmi by Molmil
Sec7 domain of ARNO, an exchange factor, at 1.5 Angstrom resolution
Descriptor: Cytohesin-2
Authors:Hoh, F, Rouhana, J.
Deposit date:2013-03-14
Release date:2013-10-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors
J.Med.Chem., 56, 2013

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