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2MHK
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BU of 2mhk by Molmil
E. coli LpoA N-terminal domain
Descriptor: Penicillin-binding protein activator LpoA
Authors:Jean, N.L, Bougault, C, Lodge, A, Derouaux, A, Callens, G, Egan, A, Lewis, R.J, Vollmer, W, Simorre, J.
Deposit date:2013-11-26
Release date:2014-06-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Elongated Structure of the Outer-Membrane Activator of Peptidoglycan Synthesis LpoA: Implications for PBP1A Stimulation.
Structure, 22, 2014
6GP7
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BU of 6gp7 by Molmil
Cell division regulator, B. subtilis GpsB, in complex with peptide fragment of Penicillin Binding Protein PBP1A
Descriptor: Cell cycle protein GpsB, MAGNESIUM ION, PBP1A
Authors:Cleverley, R.M, Lewis, R.J.
Deposit date:2018-06-05
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.950018 Å)
Cite:The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes.
Nat Commun, 10, 2019
6GPZ
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BU of 6gpz by Molmil
Cell division regulator GpsB in complex with peptide fragment of L. monocytogenes Penicillin Binding Protein PBPA1
Descriptor: Cell cycle protein GpsB, IMIDAZOLE, LmPBPA1, ...
Authors:Cleverley, R.M, Lewis, R.J, Rutter, Z.J.
Deposit date:2018-06-07
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes.
Nat Commun, 10, 2019
4I6O
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BU of 4i6o by Molmil
Crystal structure of chemically synthesized human anaphylatoxin C3a
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Complement C3
Authors:Wang, C.I.A, Ghassemian, A, Collins, B, Lewis, R.J, Alewood, P.F, Durek, T.
Deposit date:2012-11-29
Release date:2013-02-27
Last modified:2013-03-06
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Efficient chemical synthesis of human complement protein C3a.
Chem.Commun.(Camb.), 49, 2013
4HHF
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BU of 4hhf by Molmil
Crystal Structure of chemically synthesized scorpion alpha-toxin OD1
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-toxin OD1
Authors:Wang, C.I.A, Lewis, R.J, Alewood, P.F, Durek, T.
Deposit date:2012-10-09
Release date:2013-04-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Chemical engineering and structural and pharmacological characterization of the alpha-scorpion toxin OD1.
Acs Chem.Biol., 8, 2013
7TXF
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BU of 7txf by Molmil
The allosteric binding mode of alphaD-conotoxin VxXXB
Descriptor: Acetylcholine-binding protein, Alpha-conotoxin VxXXB
Authors:Ho, T.N.T, Abraham, N, Lewis, R.J.
Deposit date:2022-02-09
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Unravelling the allosteric binding mode of alpha D-VxXXB at nicotinic acetylcholine receptors.
Front Pharmacol, 14, 2023
2VY9
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BU of 2vy9 by Molmil
Molecular architecture of the stressosome, a signal integration and transduction hub
Descriptor: ANTI-SIGMA-FACTOR ANTAGONIST
Authors:Marles-Wright, J, Grant, T, Delumeau, O, van Duinen, G, Firbank, S.J, Lewis, P.J, Murray, J.W, Newman, J.A, Quin, M.B, Race, P.R, Rohou, A, Tichelaar, W, van Heel, M, Lewis, R.J.
Deposit date:2008-07-21
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub
Science, 322, 2008
2BNJ
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BU of 2bnj by Molmil
The xylanase TA from Thermoascus aurantiacus utilizes arabinose decorations of xylan as significant substrate specificity determinants.
Descriptor: 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, ENDO-1,4-BETA-XYLANASE, alpha-L-arabinofuranose-(1-3)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose
Authors:Vardakou, M, Murray, J.W, Flint, J, Christakopoulos, P, Lewis, R.J, Gilbert, H.J.
Deposit date:2005-03-25
Release date:2005-09-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Family 10 Thermoascus Aurantiacus Xylanase Utilizes Arabinose Decorations of Xylan as Significant Substrate Specificity Determinants.
J.Mol.Biol., 352, 2005
2BNL
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BU of 2bnl by Molmil
The structure of the N-terminal domain of RsbR
Descriptor: MODULATOR PROTEIN RSBR, SODIUM ION
Authors:Murray, J.W, Delumeau, O, Lewis, R.J.
Deposit date:2005-03-28
Release date:2005-11-03
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a Nonheme Globin in Environmental Stress Signaling.
Proc.Natl.Acad.Sci.USA, 102, 2005
2C1F
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BU of 2c1f by Molmil
The structure of the family 11 xylanase from Neocallimastix patriciarum
Descriptor: BIFUNCTIONAL ENDO-1,4-BETA-XYLANASE A, CADMIUM ION
Authors:Murray, J.W, Lewis, R.J, Gilbert, H.J.
Deposit date:2005-09-14
Release date:2007-02-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Understanding the Structural Basis for Substrate and Inhibitor Recognition in Eukaryotic Gh11 Xylanases.
J.Mol.Biol., 375, 2008
5AN5
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BU of 5an5 by Molmil
B. subtilis GpsB C-terminal Domain
Descriptor: CELL CYCLE PROTEIN GPSB, GLYCEROL
Authors:Rismondo, J, Cleverley, R.M, Lane, H.V, Grohennig, S, Steglich, A, Moller, L, Krishna Mannala, G, Hain, T, Lewis, R.J, Halbedel, S.
Deposit date:2015-09-04
Release date:2015-11-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of the Bacterial Cell Division Determinant Gpsb and its Interaction with Penicillin Binding Proteins.
Mol.Microbiol., 99, 2016
2CNC
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BU of 2cnc by Molmil
Family 10 xylanase
Descriptor: CHLORIDE ION, ENDOXYLANASE, MAGNESIUM ION, ...
Authors:Xie, H, Flint, J, Vardakou, M, Lakey, J.H, Lewis, R.J, Gilbert, H.J, Dumon, C.
Deposit date:2006-05-19
Release date:2006-06-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the Structural Basis for the Difference in Thermostability Displayed by Family 10 Xylanases.
J.Mol.Biol., 360, 2006
7N0W
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BU of 7n0w by Molmil
Rigidity of loop 1 contributes to equipotency of globular and ribbon isomers of alpha-conotoxin AusIA
Descriptor: Acetylcholine-binding protein, Ribbon alpha-conotoxin AusIA
Authors:Ho, T.N.T, Abraham, N, Lewis, R.J.
Deposit date:2021-05-26
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Rigidity of loop 1 contributes to equipotency of globular and ribbon isomers of alpha-conotoxin AusIA.
Sci Rep, 11, 2021
7N0Y
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BU of 7n0y by Molmil
Rigidity of loop 1 contributes to equipotency of globular and ribbon isomers of alpha-conotoxin AusIA
Descriptor: Acetylcholine-binding protein, Globular alpha-conotoxin AusIA
Authors:Ho, T.N.T, Abraham, N, Lewis, R.J.
Deposit date:2021-05-26
Release date:2021-11-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Rigidity of loop 1 contributes to equipotency of globular and ribbon isomers of alpha-conotoxin AusIA.
Sci Rep, 11, 2021
7N43
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BU of 7n43 by Molmil
Alpha-conotoxin OmIA with unusual pharmacological properties at alpha7 nicotinic receptors
Descriptor: Acetylcholine-binding protein, Alpha-conotoxin OmIA
Authors:Ho, T.N.T, Abraham, N, Lewis, R.J.
Deposit date:2021-06-03
Release date:2021-12-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Unique Pharmacological Properties of alpha-Conotoxin OmIA at alpha 7 nAChRs.
Front Pharmacol, 12, 2021
7SKC
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BU of 7skc by Molmil
Solution structure of spider toxin Ssp1a
Descriptor: Ssp1a toxin
Authors:Wilson, D.T, Daly, N.L, Dongol, Y, Lewis, R.J.
Deposit date:2021-10-20
Release date:2022-02-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Voltage-Gated Sodium Channel Modulation by a New Spider Toxin Ssp1a Isolated From an Australian Theraphosid.
Front Pharmacol, 12, 2021
7O61
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BU of 7o61 by Molmil
Crystal structure of the C-terminal PASTA domains of Staphylococcus aureus PBP1
Descriptor: Penicillin-binding protein 1
Authors:Rao, V.A, Lewis, R.J.
Deposit date:2021-04-09
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of the C-terminal PASTA domains of Staphylococcus aureus PBP1
To Be Published
7O39
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BU of 7o39 by Molmil
Crystal structure of S. aureus DivIVA N terminal domain
Descriptor: DivIVA
Authors:Rao, V.A, Booth, S, Lewis, R.J.
Deposit date:2021-04-01
Release date:2021-04-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of S. aureus DivIVA N terminal domain
To Be Published
2EW4
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BU of 2ew4 by Molmil
Solution structure of MrIA
Descriptor: MrIA
Authors:Nilsson, K.P, Lovelace, E.S, Caesar, C.E, Tynngard, N, Alewood, P.F, Johansson, H.M, Sharpe, I.A, Lewis, R.J, Daly, N.L, Craik, D.J.
Deposit date:2005-11-02
Release date:2005-11-15
Last modified:2020-06-24
Method:SOLUTION NMR
Cite:Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter
Biopolymers, 80, 2005
5FSR
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BU of 5fsr by Molmil
Crystal structure of penicillin binding protein 6B from Escherichia coli
Descriptor: D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACD
Authors:Peters, K, Kannan, S, Rao, V.A, Bilboy, J, Vollmer, D, Erickson, S.W, Lewis, R.J, Young, K.D, Vollmer, W.
Deposit date:2016-01-07
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Redundancy of Peptidoglycan Carboxypeptidases Ensures Robust Cell Shape Maintenance in Escherichia Coli
Mbio, 7, 2016
3ZT9
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BU of 3zt9 by Molmil
The bacterial stressosome: a modular system that has been adapted to control secondary messenger signaling
Descriptor: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, SERINE PHOSPHATASE
Authors:Quin, M.B, Berrisford, J.M, Newman, J.A, Basle, A, Lewis, R.J, Marles-Wright, J.
Deposit date:2011-07-06
Release date:2012-02-22
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Bacterial Stressosome: A Modular System that Has Been Adapted to Control Secondary Messenger Signaling.
Structure, 20, 2012
3ZXN
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BU of 3zxn by Molmil
Moorella thermoacetica RsbS S58E
Descriptor: ANTI-SIGMA-FACTOR ANTAGONIST (STAS) DOMAIN PROTEIN, THIOCYANATE ION
Authors:Quin, M.B, Berrisford, J.M, Newman, J.A, Basle, A, Lewis, R.J, Marles-Wright, J.
Deposit date:2011-08-12
Release date:2012-02-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Bacterial Stressosome: A Modular System that Has Been Adapted to Control Secondary Messenger Signaling.
Structure, 20, 2012
3ZXL
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BU of 3zxl by Molmil
Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HIAXHD3
Authors:McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J.
Deposit date:2011-08-11
Release date:2012-04-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.871 Å)
Cite:Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains.
Proc.Natl.Acad.Sci.USA, 109, 2012
3ZQ4
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BU of 3zq4 by Molmil
Unusual, dual endo- and exo-nuclease activity in the degradosome explained by crystal structure analysis of RNase J1
Descriptor: CALCIUM ION, RIBONUCLEASE J 1, ZINC ION
Authors:Newman, J.A, Hewitt, L, Rodrigues, C, Solovyova, A, Harwood, C.R, Lewis, R.J.
Deposit date:2011-06-07
Release date:2011-09-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Unusual, Dual Endo- and Exonuclease Activity in the Degradosome Explained by Crystal Structure Analysis of Rnase J1.
Structure, 19, 2011
3ZTA
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BU of 3zta by Molmil
The bacterial stressosome: a modular system that has been adapted to control secondary messenger signaling
Descriptor: ANTI-SIGMA-FACTOR ANTAGONIST (STAS) DOMAIN PROTEIN
Authors:Quin, M.B, Berrisford, J.M, Newman, J.A, Basle, A, Lewis, R.J, Marles-Wright, J.
Deposit date:2011-07-06
Release date:2012-02-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Bacterial Stressosome: A Modular System that Has Been Adapted to Control Secondary Messenger Signaling.
Structure, 20, 2012

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