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1CXZ
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BU of 1cxz by Molmil
CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, PROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181)), ...
Authors:Maesaki, R, Ihara, K, Shimizu, T, Kuroda, S, Kaibuchi, K, Hakoshima, T.
Deposit date:1999-08-31
Release date:1999-10-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.
Mol.Cell, 4, 1999
1UJB
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BU of 1ujb by Molmil
Structure of the protein histidine phosphatase SixA
Descriptor: CALCIUM ION, Phosphohistidine phosphatase sixA
Authors:Hamada, K, Kato, M, Shimizu, T, Ihara, K, Mizuno, T, Hakoshima, T.
Deposit date:2003-07-31
Release date:2005-01-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay.
Genes Cells, 10, 2005
1UJC
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BU of 1ujc by Molmil
Structure of the protein histidine phosphatase SixA complexed with tungstate
Descriptor: CALCIUM ION, Phosphohistidine phosphatase sixA, TUNGSTATE(VI)ION
Authors:Hamada, K, Kato, M, Shimizu, T, Ihara, K, Mizuno, T, Hakoshima, T.
Deposit date:2003-07-31
Release date:2005-01-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay.
Genes Cells, 10, 2005
1ISN
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BU of 1isn by Molmil
Crystal structure of merlin FERM domain
Descriptor: merlin
Authors:Shimizu, T, Seto, A, Maita, N, Hamada, K, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2001-12-13
Release date:2002-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
J.Biol.Chem., 277, 2002
4ZKF
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BU of 4zkf by Molmil
Crystal structure of human phosphodiesterase 12
Descriptor: 2',5'-phosphodiesterase 12, MAGNESIUM ION
Authors:Kim, S.Y, Kohno, T, Mori, T, Kitano, K, Hakoshima, T.
Deposit date:2015-04-30
Release date:2015-06-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structure of human phosphodiesterase
To Be Published
2H9V
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BU of 2h9v by Molmil
Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632
Descriptor: (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, Rho-associated protein kinase 2
Authors:Yamaguchi, H, Miwa, Y, Kasa, M, Kitano, K, Amano, M, Kaibuchi, K, Hakoshima, T.
Deposit date:2006-06-12
Release date:2006-12-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632
J.Biochem.(Tokyo), 140, 2006
1BDJ
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BU of 1bdj by Molmil
COMPLEX STRUCTURE OF HPT DOMAIN AND CHEY
Descriptor: AEROBIC RESPIRATION CONTROL SENSOR PROTEIN ARCB, CHEY, SULFATE ION
Authors:Kato, M, Mizuno, T, Shimizu, T, Hakoshima, T.
Deposit date:1998-05-10
Release date:1999-05-11
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structure of the histidine-containing phosphotransfer (HPt) domain of the anaerobic sensor protein ArcB complexed with the chemotaxis response regulator CheY.
Acta Crystallogr.,Sect.D, 55, 1999
5B5V
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BU of 5b5v by Molmil
Structure of full-length MOB1b
Descriptor: CHLORIDE ION, MOB kinase activator 1B, ZINC ION
Authors:KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T.
Deposit date:2016-05-24
Release date:2016-07-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.193 Å)
Cite:Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
Sci Rep, 6, 2016
5B3H
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BU of 5b3h by Molmil
The crystal structure of the JACKDAW/IDD10 bound to the heterodimeric SHR-SCR complex
Descriptor: Protein SCARECROW, Protein SHORT-ROOT, ZINC ION, ...
Authors:Hirano, Y, Suyama, T, Nakagawa, M, Hakoshima, T.
Deposit date:2016-02-29
Release date:2017-03-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD
Nat Plants, 3, 2017
5B5W
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BU of 5b5w by Molmil
Crystal structure of MOB1-LATS1 NTR domain complex
Descriptor: MOB kinase activator 1B, Serine/threonine-protein kinase LATS1, ZINC ION
Authors:KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T.
Deposit date:2016-05-24
Release date:2016-07-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.957 Å)
Cite:Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
Sci Rep, 6, 2016
5B6B
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BU of 5b6b by Molmil
Complex of LATS1 and phosphomimetic MOB1b
Descriptor: CHLORIDE ION, MOB kinase activator 1B, Serine/threonine-protein kinase LATS1, ...
Authors:KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T.
Deposit date:2016-05-26
Release date:2016-07-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.536 Å)
Cite:Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
Sci Rep, 6, 2016
5B3G
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BU of 5b3g by Molmil
The crystal structure of the heterodimer of SHORT-ROOT and SCARECROW GRAS domains
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ...
Authors:Hirano, Y, Nakagawa, M, Hakoshima, T.
Deposit date:2016-02-29
Release date:2017-03-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD
Nat Plants, 3, 2017
2D11
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BU of 2d11 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF2, Radixin
Authors:Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2YVC
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BU of 2yvc by Molmil
Crystal structure of the Radixin FERM domain complexed with the NEP cytoplasmic tail
Descriptor: Neprilysin, Radixin
Authors:Terawaki, S, Kitano, K, Hakoshima, T.
Deposit date:2007-04-11
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex
J.Biol.Chem., 282, 2007
2D10
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BU of 2d10 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-1 C-terminal tail peptide
Descriptor: Ezrin-radixin-moesin binding phosphoprotein 50, Radixin
Authors:Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
1A2B
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BU of 1a2b by Molmil
HUMAN RHOA COMPLEXED WITH GTP ANALOGUE
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA
Authors:Ihara, K, Muraguchi, S, Kato, M, Shimizu, T, Shirakawa, M, Kuroda, S, Kaibuchi, K, Hakoshima, T.
Deposit date:1997-12-26
Release date:1998-06-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.
J.Biol.Chem., 273, 1998
5Y04
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BU of 5y04 by Molmil
Crystal Structure of the complex between the vinculin D1 domain and alphaE-catenin
Descriptor: Catenin alpha-1, Vinculin
Authors:Hirano, Y, Hakoshima, T.
Deposit date:2017-07-14
Release date:2018-03-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form
Genes Cells, 23, 2018
1A0A
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BU of 1a0a by Molmil
PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4/DNA COMPLEX
Descriptor: DNA (5'-D(*CP*TP*AP*GP*TP*CP*CP*CP*AP*CP*GP*TP*GP*TP*GP*AP*G )-3'), DNA (5'-D(*CP*TP*CP*AP*CP*AP*CP*GP*TP*GP*GP*GP*AP*CP*TP*AP*G )-3'), PROTEIN (PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4)
Authors:Shimizu, T, Toumoto, A, Ihara, K, Shimizu, M, Kyogoku, Y, Ogawa, N, Oshima, Y, Hakoshima, T.
Deposit date:1997-11-27
Release date:1998-03-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.
EMBO J., 16, 1997
1DPF
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BU of 1dpf by Molmil
CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, RHOA
Authors:Shimizu, T, Ihara, K, Maesaki, R, Kuroda, S, Kaibuchi, K, Hakoshima, T.
Deposit date:1999-12-27
Release date:2000-06-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism.
J.Biol.Chem., 275, 2000
1WE0
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BU of 1we0 by Molmil
Crystal structure of peroxiredoxin (AhpC) from Amphibacillus xylanus
Descriptor: AMMONIUM ION, alkyl hydroperoxide reductase C
Authors:Kitano, K, Kita, A, Hakoshima, T, Niimura, Y, Miki, K.
Deposit date:2004-05-21
Release date:2005-03-29
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of decameric peroxiredoxin (AhpC) from Amphibacillus xylanus
Proteins, 59, 2005
293D
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BU of 293d by Molmil
INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE-2: THE CRYSTAL STRUCTURE OF THE D(CG)3 AND SPERMIDINE COMPLEX
Descriptor: DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION, SODIUM ION, ...
Authors:Ohishi, H, Nakanishi, I, Inubushi, K, Van Der Marel, G.A, Van Boom, J.H, Rich, A, Wang, A.H.-J, Hakoshima, T, Tomita, K.
Deposit date:1996-10-09
Release date:1996-12-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1 Å)
Cite:Interaction between the left-handed Z-DNA and polyamine-2. The crystal structure of the d(CG)3 and spermidine complex.
FEBS Lett., 391, 1996
292D
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BU of 292d by Molmil
INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX
Descriptor: 1-(AMINOETHYL)AMINO-4-AMINOBUTANE, DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Ohishi, H, Kunisawa, S, Van Der Marel, G, Van Boom, J.H, Rich, A, Wang, A.H.-J, Tomita, K, Hakoshima, T.
Deposit date:1991-10-09
Release date:1996-12-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1 Å)
Cite:Interaction between the left-handed Z-DNA and polyamine. The crystal structure of the d(CG)3 and N-(2-aminoethyl)-1,4-diamino-butane complex.
FEBS Lett., 284, 1991
1IS8
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BU of 1is8 by Molmil
Crystal structure of rat GTPCHI/GFRP stimulatory complex plus Zn
Descriptor: GTP Cyclohydrolase I, GTP Cyclohydrolase I Feedback Regulatory Protein, PHENYLALANINE, ...
Authors:Maita, N, Okada, K, Hatakeyama, K, Hakoshima, T.
Deposit date:2001-11-18
Release date:2002-02-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.
Proc.Natl.Acad.Sci.USA, 99, 2002
7DCH
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BU of 7dch by Molmil
Alpha-glucosidase from Weissella cibaria BBK-1 bound with acarbose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-glycosidase, ...
Authors:Krusong, K, Wangpaiboon, K, Kim, S, Mori, T, Hakoshima, T.
Deposit date:2020-10-26
Release date:2021-08-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.692 Å)
Cite:A GH13 alpha-glucosidase from Weissella cibaria uncommonly acts on short-chain maltooligosaccharides.
Acta Crystallogr D Struct Biol, 77, 2021
7D9C
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Alpha-glucosidase from Weissella cibaria BBK-1 bound with maltose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Alpha-glycosidase, CALCIUM ION, ...
Authors:Krusong, K, Wangpaiboon, K, Kim, S, Mori, T, Hakoshima, T.
Deposit date:2020-10-13
Release date:2021-08-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:A GH13 alpha-glucosidase from Weissella cibaria uncommonly acts on short-chain maltooligosaccharides.
Acta Crystallogr D Struct Biol, 77, 2021

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