1CXZ
 
 | | CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1 | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, PROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181)), ... | | Authors: | Maesaki, R, Ihara, K, Shimizu, T, Kuroda, S, Kaibuchi, K, Hakoshima, T. | | Deposit date: | 1999-08-31 | | Release date: | 1999-10-08 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.
Mol.Cell, 4, 1999
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1UJB
 | | Structure of the protein histidine phosphatase SixA | | Descriptor: | CALCIUM ION, Phosphohistidine phosphatase sixA | | Authors: | Hamada, K, Kato, M, Shimizu, T, Ihara, K, Mizuno, T, Hakoshima, T. | | Deposit date: | 2003-07-31 | | Release date: | 2005-01-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay.
Genes Cells, 10, 2005
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1UJC
 | | Structure of the protein histidine phosphatase SixA complexed with tungstate | | Descriptor: | CALCIUM ION, Phosphohistidine phosphatase sixA, TUNGSTATE(VI)ION | | Authors: | Hamada, K, Kato, M, Shimizu, T, Ihara, K, Mizuno, T, Hakoshima, T. | | Deposit date: | 2003-07-31 | | Release date: | 2005-01-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay.
Genes Cells, 10, 2005
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1ISN
 | | Crystal structure of merlin FERM domain | | Descriptor: | merlin | | Authors: | Shimizu, T, Seto, A, Maita, N, Hamada, K, Tsukita, S, Tsukita, S, Hakoshima, T. | | Deposit date: | 2001-12-13 | | Release date: | 2002-04-03 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
J.Biol.Chem., 277, 2002
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4ZKF
 | | Crystal structure of human phosphodiesterase 12 | | Descriptor: | 2',5'-phosphodiesterase 12, MAGNESIUM ION | | Authors: | Kim, S.Y, Kohno, T, Mori, T, Kitano, K, Hakoshima, T. | | Deposit date: | 2015-04-30 | | Release date: | 2015-06-17 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Crystal structure of human phosphodiesterase
To Be Published
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2H9V
 | | Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632 | | Descriptor: | (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, Rho-associated protein kinase 2 | | Authors: | Yamaguchi, H, Miwa, Y, Kasa, M, Kitano, K, Amano, M, Kaibuchi, K, Hakoshima, T. | | Deposit date: | 2006-06-12 | | Release date: | 2006-12-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632
J.Biochem.(Tokyo), 140, 2006
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1BDJ
 | | COMPLEX STRUCTURE OF HPT DOMAIN AND CHEY | | Descriptor: | AEROBIC RESPIRATION CONTROL SENSOR PROTEIN ARCB, CHEY, SULFATE ION | | Authors: | Kato, M, Mizuno, T, Shimizu, T, Hakoshima, T. | | Deposit date: | 1998-05-10 | | Release date: | 1999-05-11 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Structure of the histidine-containing phosphotransfer (HPt) domain of the anaerobic sensor protein ArcB complexed with the chemotaxis response regulator CheY.
Acta Crystallogr.,Sect.D, 55, 1999
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5B5V
 | | Structure of full-length MOB1b | | Descriptor: | CHLORIDE ION, MOB kinase activator 1B, ZINC ION | | Authors: | KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T. | | Deposit date: | 2016-05-24 | | Release date: | 2016-07-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.193 Å) | | Cite: | Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
Sci Rep, 6, 2016
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5B3H
 | | The crystal structure of the JACKDAW/IDD10 bound to the heterodimeric SHR-SCR complex | | Descriptor: | Protein SCARECROW, Protein SHORT-ROOT, ZINC ION, ... | | Authors: | Hirano, Y, Suyama, T, Nakagawa, M, Hakoshima, T. | | Deposit date: | 2016-02-29 | | Release date: | 2017-03-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD
Nat Plants, 3, 2017
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5B5W
 | | Crystal structure of MOB1-LATS1 NTR domain complex | | Descriptor: | MOB kinase activator 1B, Serine/threonine-protein kinase LATS1, ZINC ION | | Authors: | KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T. | | Deposit date: | 2016-05-24 | | Release date: | 2016-07-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.957 Å) | | Cite: | Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
Sci Rep, 6, 2016
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5B6B
 | | Complex of LATS1 and phosphomimetic MOB1b | | Descriptor: | CHLORIDE ION, MOB kinase activator 1B, Serine/threonine-protein kinase LATS1, ... | | Authors: | KIM, S.-Y, Tachioka, Y, Mori, T, Hakoshima, T. | | Deposit date: | 2016-05-26 | | Release date: | 2016-07-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.536 Å) | | Cite: | Structural basis for autoinhibition and its relief of MOB1 in the Hippo pathway
Sci Rep, 6, 2016
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5B3G
 | | The crystal structure of the heterodimer of SHORT-ROOT and SCARECROW GRAS domains | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | | Authors: | Hirano, Y, Nakagawa, M, Hakoshima, T. | | Deposit date: | 2016-02-29 | | Release date: | 2017-03-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD
Nat Plants, 3, 2017
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2D11
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2YVC
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2D10
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1A2B
 | | HUMAN RHOA COMPLEXED WITH GTP ANALOGUE | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA | | Authors: | Ihara, K, Muraguchi, S, Kato, M, Shimizu, T, Shirakawa, M, Kuroda, S, Kaibuchi, K, Hakoshima, T. | | Deposit date: | 1997-12-26 | | Release date: | 1998-06-17 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.
J.Biol.Chem., 273, 1998
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5Y04
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1A0A
 | | PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4/DNA COMPLEX | | Descriptor: | DNA (5'-D(*CP*TP*AP*GP*TP*CP*CP*CP*AP*CP*GP*TP*GP*TP*GP*AP*G )-3'), DNA (5'-D(*CP*TP*CP*AP*CP*AP*CP*GP*TP*GP*GP*GP*AP*CP*TP*AP*G )-3'), PROTEIN (PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4) | | Authors: | Shimizu, T, Toumoto, A, Ihara, K, Shimizu, M, Kyogoku, Y, Ogawa, N, Oshima, Y, Hakoshima, T. | | Deposit date: | 1997-11-27 | | Release date: | 1998-03-18 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.
EMBO J., 16, 1997
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1DPF
 | | CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, RHOA | | Authors: | Shimizu, T, Ihara, K, Maesaki, R, Kuroda, S, Kaibuchi, K, Hakoshima, T. | | Deposit date: | 1999-12-27 | | Release date: | 2000-06-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism.
J.Biol.Chem., 275, 2000
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1WE0
 | | Crystal structure of peroxiredoxin (AhpC) from Amphibacillus xylanus | | Descriptor: | AMMONIUM ION, alkyl hydroperoxide reductase C | | Authors: | Kitano, K, Kita, A, Hakoshima, T, Niimura, Y, Miki, K. | | Deposit date: | 2004-05-21 | | Release date: | 2005-03-29 | | Last modified: | 2018-02-07 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of decameric peroxiredoxin (AhpC) from Amphibacillus xylanus
Proteins, 59, 2005
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293D
 | | INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE-2: THE CRYSTAL STRUCTURE OF THE D(CG)3 AND SPERMIDINE COMPLEX | | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION, SODIUM ION, ... | | Authors: | Ohishi, H, Nakanishi, I, Inubushi, K, Van Der Marel, G.A, Van Boom, J.H, Rich, A, Wang, A.H.-J, Hakoshima, T, Tomita, K. | | Deposit date: | 1996-10-09 | | Release date: | 1996-12-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Interaction between the left-handed Z-DNA and polyamine-2. The crystal structure of the d(CG)3 and spermidine complex.
FEBS Lett., 391, 1996
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292D
 | | INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX | | Descriptor: | 1-(AMINOETHYL)AMINO-4-AMINOBUTANE, DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION, ... | | Authors: | Ohishi, H, Kunisawa, S, Van Der Marel, G, Van Boom, J.H, Rich, A, Wang, A.H.-J, Tomita, K, Hakoshima, T. | | Deposit date: | 1991-10-09 | | Release date: | 1996-12-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Interaction between the left-handed Z-DNA and polyamine. The crystal structure of the d(CG)3 and N-(2-aminoethyl)-1,4-diamino-butane complex.
FEBS Lett., 284, 1991
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1IS8
 | | Crystal structure of rat GTPCHI/GFRP stimulatory complex plus Zn | | Descriptor: | GTP Cyclohydrolase I, GTP Cyclohydrolase I Feedback Regulatory Protein, PHENYLALANINE, ... | | Authors: | Maita, N, Okada, K, Hatakeyama, K, Hakoshima, T. | | Deposit date: | 2001-11-18 | | Release date: | 2002-02-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.
Proc.Natl.Acad.Sci.USA, 99, 2002
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7DCH
 | | Alpha-glucosidase from Weissella cibaria BBK-1 bound with acarbose | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, Alpha-glycosidase, ... | | Authors: | Krusong, K, Wangpaiboon, K, Kim, S, Mori, T, Hakoshima, T. | | Deposit date: | 2020-10-26 | | Release date: | 2021-08-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.692 Å) | | Cite: | A GH13 alpha-glucosidase from Weissella cibaria uncommonly acts on short-chain maltooligosaccharides.
Acta Crystallogr D Struct Biol, 77, 2021
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7D9C
 | | Alpha-glucosidase from Weissella cibaria BBK-1 bound with maltose | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Alpha-glycosidase, CALCIUM ION, ... | | Authors: | Krusong, K, Wangpaiboon, K, Kim, S, Mori, T, Hakoshima, T. | | Deposit date: | 2020-10-13 | | Release date: | 2021-08-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | A GH13 alpha-glucosidase from Weissella cibaria uncommonly acts on short-chain maltooligosaccharides.
Acta Crystallogr D Struct Biol, 77, 2021
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