9K6R
 
 | | Cryo-EM Structure of hAGO2D669A-siRNA-target (14-nt, uni-lobed) | | Descriptor: | MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*GP*AP*AP*AP*GP*GP*CP*UP*CP*UP*UP*GP*UP*U)-3'), ... | | Authors: | Li, Z.Z, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-10-22 | | Release date: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Mechanistic insights into RNA cleavage by human Argonaute2-siRNA complex.
Cell Res., 35, 2025
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9K6T
 | | Cryo-EM Structure of hAGO2D669A-siRNA-target (21-nt) | | Descriptor: | MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*AP*AP*CP*AP*AP*CP*AP*GP*AP*AP*AP*GP*GP*CP*UP*CP*UP*UP*GP*UP*U)-3'), ... | | Authors: | Li, Z.Z, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-10-22 | | Release date: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Mechanistic insights into RNA cleavage by human Argonaute2-siRNA complex.
Cell Res., 35, 2025
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9K6S
 | | Cryo-EM Structure of hAGO2D669A-siRNA-target (19-nt) | | Descriptor: | MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*CP*AP*AP*CP*AP*GP*AP*AP*AP*GP*GP*CP*UP*CP*UP*UP*GP*UP*U)-3'), ... | | Authors: | Li, Z.Z, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-10-22 | | Release date: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Mechanistic insights into RNA cleavage by human Argonaute2-siRNA complex.
Cell Res., 35, 2025
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9K6Q
 | | "Cryo-EM Structure of hAGO2D669A-siRNA-target (14-nt, sesqui-lobed) | | Descriptor: | MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*GP*AP*AP*AP*GP*GP*CP*UP*CP*UP*UP*GP*U)-3'), ... | | Authors: | Li, Z.Z, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-10-22 | | Release date: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Mechanistic insights into RNA cleavage by human Argonaute2-siRNA complex.
Cell Res., 35, 2025
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7YG6
 | | Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA | | Descriptor: | MAGNESIUM ION, Piwi, piRNA | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-11 | | Release date: | 2024-01-24 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YFX
 | | Cryo-EM structure of Hili in complex with piRNA | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, piRNA | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-09 | | Release date: | 2024-01-24 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YGN
 | | Cryo-EM structure of the Mili in complex with piRNA | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, piRNA | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-11 | | Release date: | 2024-01-24 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YFQ
 | | Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex | | Descriptor: | MAGNESIUM ION, Piwi, RNA (5'-R(*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-08 | | Release date: | 2024-02-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YFY
 | | Cryo-EM structure of the Mili-piRNA- target ternary complex | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, RNA (5'-R(P*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-09 | | Release date: | 2024-01-24 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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3OHI
 | | Structure of Giardia fructose-1,6-biphosphate aldolase in complex with 3-hydroxy-2-pyridone | | Descriptor: | ({3-hydroxy-2-oxo-4-[2-(phosphonooxy)ethyl]pyridin-1(2H)-yl}methyl)phosphonic acid, Putative fructose-1,6-bisphosphate aldolase, ZINC ION | | Authors: | Herzberg, O, Galkin, A. | | Deposit date: | 2010-08-17 | | Release date: | 2011-01-19 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Rational design, synthesis and evaluation of first generation inhibitors of the Giardia lamblia fructose-1,6-biphosphate aldolase.
J.Inorg.Biochem., 105, 2010
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9IJ1
 | | Cryo-EM Structure of MILI-piRNA-target (22-nt, bilobed) | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, RNA (26-MER), ... | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IIY
 | | Cryo-EM Structure of EfPiwi-piRNA-target (25-nt, bilobed) | | Descriptor: | Piwi, RNA (5'-R(P*CP*GP*UP*CP*UP*AP*UP*AP*CP*AP*AP*CP*CP*GP*AP*UP*CP*AP*GP*CP*U)-3'), RNA (5'-R(P*UP*AP*GP*CP*AP*GP*AP*UP*CP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*AP*CP*G)-3') | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IJ4
 | | Cryo-EM Structure of MILI(K852A)-piRNA-target (26-nt) | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, RNA (25-MER), ... | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2025-01-22 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IJ5
 | | Cryo-EM Structure of MILI(K853A)-piRNA-target | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, RNA (25-MER), ... | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IJ3
 | | Cryo-EM Structure of MILI-piRNA-target (26-nt) | | Descriptor: | MANGANESE (II) ION, Piwi-like protein 2, RNA (25-MER), ... | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IJ0
 | | Cryo-EM Structure of MILI-piRNA-target (8-nt) | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, RNA (26-MER), ... | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IJ2
 | | Cryo-EM Structure of MILI-piRNA-target (22-nt, comma) | | Descriptor: | Piwi-like protein 2, RNA (5'-R(P*CP*AP*AP*GP*UP*UP*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*A)-3'), RNA (5'-R(P*UP*UP*AP*CP*CP*AP*UP*CP*AP*AP*CP*AP*UP*GP*GP*AP*AP*AP*CP*UP*UP*G)-3') | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IIZ
 | | Cryo-EM Structure of EfPiwi-piRNA-target (25-nt, comma) | | Descriptor: | Piwi, RNA (25-MER), RNA (5'-R(P*AP*GP*CP*CP*AP*AP*GP*UP*UP*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*A)-3') | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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6KWF
 | | Crystal Structure Analysis of Endo-beta-1,4-xylanase II Complexed with Xylotriose | | Descriptor: | Endo-1,4-beta-xylanase 2, GLYCEROL, IODIDE ION, ... | | Authors: | Li, C, Wan, Q. | | Deposit date: | 2019-09-06 | | Release date: | 2020-12-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.22 Å) | | Cite: | Studying the Role of a Single Mutation of a Family 11 Glycoside Hydrolase Using High-Resolution X-ray Crystallography.
Protein J., 39, 2020
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6KWG
 | | Crystal Structure Analysis of Endo-beta-1,4-xylanase II Complexed with Xylotriose | | Descriptor: | Endo-1,4-beta-xylanase 2, IODIDE ION, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | | Authors: | Li, C, Wan, Q. | | Deposit date: | 2019-09-06 | | Release date: | 2020-12-30 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.694 Å) | | Cite: | Studying the Role of a Single Mutation of a Family 11 Glycoside Hydrolase Using High-Resolution X-ray Crystallography.
Protein J., 39, 2020
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6KWC
 | | Crystal Structure Analysis of Endo-beta-1,4-xylanase II | | Descriptor: | Endo-1,4-beta-xylanase 2, GLYCEROL, IODIDE ION | | Authors: | Li, C, Wan, Q. | | Deposit date: | 2019-09-06 | | Release date: | 2021-01-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Studying the Role of a Single Mutation of a Family 11 Glycoside Hydrolase Using High-Resolution X-ray Crystallography.
Protein J., 39, 2020
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9JE9
 | | Crystal structure of a amidase that can hydrolase PU plastic | | Descriptor: | Amidase | | Authors: | Li, Z.S, Fang, S.T, Zheng, Z.R, Xia, W, Zhou, H.Y, Li, W.S, You, S, Han, X, Liu, W.D. | | Deposit date: | 2024-09-02 | | Release date: | 2025-07-09 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Discovery and Engineering of a Urethanase for Enhanced Depolymerization of Polyurethane
Acs Catalysis, 15, 2025
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5H5Z
 | | Crystal structure of bony fish MHC class I, peptide and B2m II | | Descriptor: | Beta-2-microglobulin, MHC class I antigen, peptide chain | | Authors: | Chen, Z, Zhang, N, Qi, J, Li, X, Chen, R, Wang, Z, Gao, F.G, Xia, C. | | Deposit date: | 2016-11-10 | | Release date: | 2017-11-22 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | The Mechanism of beta 2m Molecule-Induced Changes in the Peptide Presentation Profile in a Bony Fish.
Iscience, 23, 2020
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6IGD
 | | Crystal structure of HPV58/33 chimeric L1 pentamer | | Descriptor: | Major capsid protein L1 | | Authors: | Li, Z.H, Song, S, He, M.Z, Gu, Y, Li, S.W. | | Deposit date: | 2018-09-25 | | Release date: | 2018-11-21 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
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6IGF
 | | Crystal structure of Human Papillomavirus type 52 pentamer | | Descriptor: | Major capsid protein L1 | | Authors: | Li, Z.H, Song, S, He, M.Z, Gu, Y, Li, S.W. | | Deposit date: | 2018-09-25 | | Release date: | 2018-11-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.751 Å) | | Cite: | Rational design of a triple-type human papillomavirus vaccine by compromising viral-type specificity.
Nat Commun, 9, 2018
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